YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis

Diagnosis and Treatment of Helicobacter pylori Infection

(2022) Yi-Chia Lee et al.   Annual Review of Medicine

Helicobacter pylori-induced RASAL2 through activation of NF-kB promotes gastric tumorigenesis via β-catenin signaling axis

(2022) Longlong Cao et al.   GASTROENTEROLOGY

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

(2022) Ellen Youngsoo Rim et al.   Annual Review of Biochemistry

β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma

(2022) Yi Zhang et al.   GASTROENTEROLOGY

Effect of Helicobacter pylori Eradication on Gastric Cancer Prevention: Updated Report From a Randomized Controlled Trial With 26.5 Years of Follow-up

(2022) Lingjun Yan et al.   GASTROENTEROLOGY

Recent insight into the role and therapeutic potential of YAP/TAZ in gastrointestinal cancers

(2022) Yifei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer

(2021) Hazel M. Quinn et al.   CANCER RESEARCH

Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis

(2021) Satoshi Imai et al.   Cell Host & Microbe

Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration

(2021) Oriane Guillermin et al.   EMBO JOURNAL

Dysregulation of the ESRP2-NF2-YAP/TAZ axis promotes hepatobiliary carcinogenesis in non-alcoholic fatty liver disease

(2021) Jeongeun Hyun et al.   JOURNAL OF HEPATOLOGY

Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial‐mesenchymal transition via the MEK/ERK pathway

(2021) Nianshuang Li et al.   HELICOBACTER

Upregulation of oncogene Activin A receptor type I by Helicobacter pylori infection promotes gastric intestinal metaplasia via regulating CDX2

(2021) Hong‐Yan Chen et al.   HELICOBACTER

Lifestyles, genetics, and future perspectives on gastric cancer in east Asian populations

(2021) Hiroto Katoh et al.   JOURNAL OF HUMAN GENETICS

RUVBL1/2 Complex Regulates Pro-Inflammatory Responses in Macrophages via Regulating Histone H3K4 Trimethylation

(2021) Rui Zhang et al.   Frontiers in Immunology

Small molecule-induced simultaneous destabilization of β-catenin and RAS is an effective molecular strategy to suppress stemness of colorectal cancer cells

(2020) Yong-Hee Cho et al.   Cell Communication and Signaling

Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer

(2020) Won-Ji Ryu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Integrative Analysis of Differential lncRNA/mRNA Expression Profiling in Helicobacter pylori Infection-Associated Gastric Carcinogenesis

(2020) Nianshuang Li et al.   Frontiers in Microbiology

Mass eradication of Helicobacter pylori to reduce gastric cancer incidence and mortality: a long-term cohort study on Matsu Islands

(2020) Tsung-Hsien Chiang et al.   GUT

H. pylori infection alters repair of DNA double-strand breaks via SNHG17

(2020) Taotao Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of autophagy aggravates DNA damage response and gastric tumorigenesis via Rad51 ubiquitination in response to H. pylori infection

(2020) Chuan Xie et al.   Gut Microbes

Hippo Signaling in Embryogenesis and Development

(2020) Zhengming Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Telomere dysfunction activates YAP1 to drive tissue inflammation

(2020) Deepavali Chakravarti et al.   Nature Communications

Caudal type homeoboxes as a driving force in Helicobacter pylori infection-induced gastric intestinal metaplasia

(2020) Hong-Yan Chen et al.   Gut Microbes

Targeting the Wnt/β-catenin signaling pathway in cancer

(2020) Ya Zhang et al.   Journal of Hematology & Oncology

Helicobacter pylori Infection

(2019) Sheila E. Crowe   NEW ENGLAND JOURNAL OF MEDICINE

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

The Hippo and Wnt signalling pathways: crosstalk during neoplastic progression in gastrointestinal tissue

(2019) Nianshuang Li et al.   FEBS Journal

The Hippo Signaling Pathway in Development and Disease

(2019) Yonggang Zheng et al.   DEVELOPMENTAL CELL

SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

(2018) Lan Fang et al.   CANCER CELL

YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

(2018) Feihong Deng et al.   Cell Death & Disease

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Hippo Pathway: Biology and Pathophysiology

(2018) Shenghong Ma et al.   Annual Review of Biochemistry

Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway

(2018) Nianshuang Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer

(2016) Xin Yong et al.   CANCER LETTERS

Helicobacter pylori- induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32

(2016) Shoumin Zhu et al.   GUT

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

(2016) Pu-Hyeon Cha et al.   Nature Chemical Biology

Helicobacter pylori Activates and Expands Lgr5+ Stem Cells Through Direct Colonization of the Gastric Glands

(2015) Michael Sigal et al.   GASTROENTEROLOGY

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

(2014) Junyan Tao et al.   GASTROENTEROLOGY

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

(2012) Masamichi Imajo et al.   EMBO JOURNAL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE