Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation
Published 2016 View Full Article
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Title
Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation
Authors
Keywords
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Journal
Nature Chemical Biology
Volume 12, Issue 8, Pages 593-600
Publisher
Springer Nature
Online
2016-06-14
DOI
10.1038/nchembio.2103
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Related references
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- Mutated K-rasAsp12promotes tumourigenesis inApcMinmice more in the large than the small intestines, with synergistic effects between K-rasandWntpathways
- (2009) Feijun Luo et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- H-Ras is degraded by Wnt/ -catenin signaling via -TrCP-mediated polyubiquitylation
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- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
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