β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

(2021) Silvia Affo et al.   CANCER CELL

The hippo pathway: A master regulator of liver metabolism, regeneration, and disease

(2021) Anh Thu Nguyen‐Lefebvre et al.   FASEB JOURNAL

Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation

(2021) Xinhua Song et al.   JOURNAL OF HEPATOLOGY

YAP/TAZ functions and their regulation at a glance

(2020) Arianna Pocaterra et al.   JOURNAL OF CELL SCIENCE

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

(2020) Jesus M. Banales et al.   Nature Reviews Gastroenterology & Hepatology

WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

(2019) Yu-An Chen et al.   Frontiers in Oncology

YAP and the Hippo pathway in cholangiocarcinoma

(2019) Takaaki Sugihara et al.   JOURNAL OF GASTROENTEROLOGY

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma

(2019) Jie Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt/β-Catenin Signaling in Liver Cancers

(2019) Wenhui Wang et al.   Cancers

Role of Cancer Stem Cells in Cholangiocarcinoma and Therapeutic Implications

(2019) Hsing-Ju Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prognostic value of site-specific metastases for patients with advanced intrahepatic cholangiocarcinoma

(2019) Rui Cheng et al.   MEDICINE

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

(2018) Jingxiao Wang et al.   ONCOGENE

YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

(2018) Feihong Deng et al.   Cell Death & Disease

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice

(2018) Yu Qiao et al.   BMC CANCER

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

(2018) Lei Chang et al.   NATURE

Wnt–β-catenin signalling in liver development, health and disease

(2018) Maria J. Perugorria et al.   Nature Reviews Gastroenterology & Hepatology

Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice

(2017) Junyan Tao et al.   HEPATOLOGY

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice

(2017) Shanshan Zhang et al.   JOURNAL OF HEPATOLOGY

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH -Mutant Molecular Profiles

(2017) Farshad Farshidfar et al.   Cell Reports

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Hydrodynamic Transfection for Generation of Novel Mouse Models for Liver Cancer Research

(2014) Xin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

(2012) Masamichi Imajo et al.   EMBO JOURNAL

Cholangiocarcinomas can originate from hepatocytes in mice

(2012) Biao Fan et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner

(2010) Eline Remue et al.   FEBS LETTERS

Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma

(2010) Diego F. Calvisi et al.   GASTROENTEROLOGY

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY