Application of Enzyme Coupling Reactions to Shift Thermodynamically Limited Biocatalytic Reactions

A Practical and Fast Method To Predict the Thermodynamic Preference of ω-Transaminase-Based Transformations

(2015) Robert J. Meier et al.   ChemCatChem

A Bi-enzymatic Convergent Cascade for ε-Caprolactone Synthesis Employing 1,6-Hexanediol as a ‘Double-Smart Cosubstrate’

(2015) Amin Bornadel et al.   ChemCatChem

Asymmetric Biocatalytic Amination of Ketones at the Expense of NH3 and Molecular Hydrogen

(2015) Anja K. Holzer et al.   ORGANIC LETTERS

Amine donor and acceptor influence on the thermodynamics of ω-transaminase reactions

(2015) Maria T. Gundersen et al.   TETRAHEDRON-ASYMMETRY

Phenylalanine Ammonia Lyase Catalyzed Synthesis of Amino Acids by an MIO-Cofactor Independent Pathway

(2014) Sarah L. Lovelock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

How Green is Biocatalysis? To Calculate is To Know

(2014) Yan Ni et al.   ChemCatChem

Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase

(2014) Nina Richter et al.   CHEMICAL COMMUNICATIONS

Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems

(2014) Werner Hummel et al.   JOURNAL OF BIOTECHNOLOGY

In vitro characterization of an enzymatic redox cascade composed of an alcohol dehydrogenase, an enoate reductases and a Baeyer–Villiger monooxygenase

(2014) Nikolin Oberleitner et al.   JOURNAL OF BIOTECHNOLOGY

Supported liquid membrane as a novel tool for driving the equilibrium of ω-transaminase catalyzed asymmetric synthesis

(2014) Gustav Rehn et al.   JOURNAL OF BIOTECHNOLOGY

Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism

(2014) Elad Noor et al.   PLoS Computational Biology

The Evolution of an Amine Dehydrogenase Biocatalyst for the Asymmetric Production of Chiral Amines

(2013) Michael J. Abrahamson et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent trends and novel concepts in cofactor-dependent biotransformations

(2013) Selin Kara et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The role of activity coefficients in bioreaction equilibria: Thermodynamics of methyl ferulate hydrolysis

(2013) Philip Hoffmann et al.   BIOPHYSICAL CHEMISTRY

A model to assess the feasibility of shifting reaction equilibrium by acetone removal in the transamination of ketones using 2-propylamine

(2013) Pär Tufvesson et al.   BIOTECHNOLOGY AND BIOENGINEERING

One-Pot Production of Enantiopure Alkylamines and Arylalkylamines of Opposite Chirality Catalyzed by ω-Transaminase

(2013) Eul-Soo Park et al.   ChemCatChem

Artificial Multi-Enzyme Networks for the Asymmetric Amination ofsec-Alcohols

(2013) Katharina Tauber et al.   CHEMISTRY-A EUROPEAN JOURNAL

ω-Transaminase-catalyzed asymmetric synthesis of unnatural amino acids using isopropylamine as an amino donor

(2013) Eul-Soo Park et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Reaction Engineering of Biocatalytic Enantioselective Reduction: A Case Study for Aliphatic Ketones

(2013) Susanne Leuchs et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Recent Developments of Cascade Reactions Involving ω-Transaminases

(2013) Robert C. Simon et al.   ACS Catalysis

Redox Self-Sufficient Biocatalyst Network for the Amination of Primary Alcohols

(2012) Johann H. Sattler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An integrated open framework for thermodynamics of reactions that combines accuracy and coverage

(2012) Elad Noor et al.   BIOINFORMATICS

Experimental determination of thermodynamic equilibrium in biocatalytic transamination

(2012) Pär Tufvesson et al.   BIOTECHNOLOGY AND BIOENGINEERING

A biocatalytic redox isomerisation

(2012) Serena Gargiulo et al.   CHEMICAL COMMUNICATIONS

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

(2012) Bo Wang et al.   CHEMICAL COMMUNICATIONS

Group-contribution+ (GC+) based estimation of properties of pure components: Improved property estimation and uncertainty analysis

(2012) Amol Shivajirao Hukkerikar et al.   FLUID PHASE EQUILIBRIA

Enantioselective reduction of sparingly water-soluble ketones: continuous process and recycle of the aqueous buffer system

(2012) Susanne Leuchs et al.   GREEN CHEMISTRY

More efficient redox biocatalysis by utilising 1,4-butanediol as a ‘smart cosubstrate’

(2012) Selin Kara et al.   GREEN CHEMISTRY

Characterization of a Novel N-Acetylneuraminate Lyase from Staphylococcus carnosus TM300 and Its Application to N-Acetylneuraminic Acid Production

(2012) María Inmaculada García García et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids

(2012) Hans Raj et al.   Nature Chemistry

Stereoselectivity of Four (R)-Selective Transaminases for the Asymmetric Amination of Ketones

(2011) Francesco G. Mutti et al.   ADVANCED SYNTHESIS & CATALYSIS

Recommendations for terminology and databases for biochemical thermodynamics

(2011) Robert A. Alberty et al.   BIOPHYSICAL CHEMISTRY

Process considerations for the asymmetric synthesis of chiral amines using transaminases

(2011) Pär Tufvesson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Amination of Ketones by Employing Two New (S)-Selective ω-Transaminases and the His-Tagged ω-TA from Vibrio fluvialis

(2011) Francesco G. Mutti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases

(2010) Joo-Hyun Seo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Transaminations with isopropyl amine: equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration

(2010) Karim Engelmark Cassimjee et al.   CHEMICAL COMMUNICATIONS

Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst

(2010) Andreas S Bommarius et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Measuring and Modeling Activity Coefficients in Aqueous Amino-Acid Solutions

(2010) Christoph Held et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases

(2009) Matthew D. Truppo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases

(2008) Dominik Koszelewski et al.   ADVANCED SYNTHESIS & CATALYSIS

Group Contribution Method for Thermodynamic Analysis of Complex Metabolic Networks

(2008) Matthew D. Jankowski et al.   BIOPHYSICAL JOURNAL

Asymmetric Synthesis of (S)-α-Methylbenzylamine by RecombinantEscherichia coliCo-Expressing Omega-Transaminase and Acetolactate Synthase

(2008) Hyungdon YUN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase

(2008) Matthias Höhne et al.   CHEMBIOCHEM

Asymmetric Bioreduction of Activated C=C Bonds UsingZymomonas mobilis NCR Enoate Reductase and Old Yellow Enzymes OYE 1–3 from Yeasts

(2008) Mélanie Hall et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Rapid screening and scale-up of transaminase catalysed reactions

(2008) Matthew D. Truppo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Options for biochemical production of 4-hydroxybutyrate and its lactone as a substitute for petrochemical production

(2007) C. Efe et al.   BIOTECHNOLOGY AND BIOENGINEERING

Future directions forin-situ product removal (ISPR)

(2007) John M Woodley et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY