Process considerations for the asymmetric synthesis of chiral amines using transaminases

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases

(2010) Joo-Hyun Seo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Kinetic resolution of α-methylbenzylamine by recombinant Pichia pastoris expressing ω-transaminase

(2010) Han-Seop Bea et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Transaminations with isopropyl amine: equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration

(2010) Karim Engelmark Cassimjee et al.   CHEMICAL COMMUNICATIONS

New Trends in the Recycling of NAD(P)H for the Design of Sustainable Asymmetric Reductions Catalyzed by Dehydrogenases

(2010) Angel Berenguer-Murcia et al.   CURRENT ORGANIC CHEMISTRY

Process considerations for the scale-up and implementation of biocatalysis

(2010) Pär Tufvesson et al.   FOOD AND BIOPRODUCTS PROCESSING

Multienzyme-Catalyzed Processes: Next-Generation Biocatalysis

(2010) Paloma A. Santacoloma et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Guidelines and Cost Analysis for Catalyst Production in Biocatalytic Processes

(2010) Pär Tufvesson et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase

(2010) M. P. Frushicheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Testing of microorganisms for ω-transaminase activity

(2010) Dorina Clay et al.   TETRAHEDRON-ASYMMETRY

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Synthesis of Optically Active Amines Employing Recombinant ω-Transaminases inE. coliCells

(2009) Dominik Koszelewski et al.   ChemCatChem

Efficient kinetic resolution of racemic amines using a transaminase in combination with an amino acid oxidase

(2009) Matthew D. Truppo et al.   CHEMICAL COMMUNICATIONS

Directed enzyme evolution: climbing fitness peaks one amino acid at a time

(2009) Cara A Tracewell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Deracemisation of α-Chiral Primary Amines by a One-Pot, Two-Step Cascade Reaction Catalysed by ω-Transaminases

(2009) Dominik Koszelewski et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Immobilization of ω-transaminases by encapsulation in a sol–gel/celite matrix

(2009) Dominik Koszelewski et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases

(2009) Matthew D. Truppo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase fromBacillus megaterium

(2008) Ronald L. Hanson et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases

(2008) Dominik Koszelewski et al.   ADVANCED SYNTHESIS & CATALYSIS

Group Contribution Method for Thermodynamic Analysis of Complex Metabolic Networks

(2008) Matthew D. Jankowski et al.   BIOPHYSICAL JOURNAL

Asymmetric Synthesis of (S)-α-Methylbenzylamine by RecombinantEscherichia coliCo-Expressing Omega-Transaminase and Acetolactate Synthase

(2008) Hyungdon YUN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway

(2008) Joon-Young Hwang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase

(2008) Matthias Höhne et al.   CHEMBIOCHEM

Rapid screening and scale-up of transaminase catalysed reactions

(2008) Matthew D. Truppo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Future directions forin-situ product removal (ISPR)

(2007) John M Woodley et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Asymmetrical Synthesis of l-Homophenylalanine Using Engineered Escherichia coli Aspartate Aminotransferase

(2005) Hsueh-Hsia Lo et al.   BIOTECHNOLOGY PROGRESS