Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase

Asymmetric Synthesis of 3-Substituted Cyclohexylamine Derivatives from Prochiral DiketonesviaThree Biocatalytic Steps

(2013) Elina Siirola et al.   ADVANCED SYNTHESIS & CATALYSIS

Two Steps in One Pot: Enzyme Cascade for the Synthesis of Nor(pseudo)ephedrine from Inexpensive Starting Materials

(2013) Torsten Sehl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic Asymmetric Synthesis of Unnatural Amino Acids through the Cascade Transfer of Amino Groups from Primary Amines onto Keto Acids

(2013) Eul-Soo Park et al.   ChemCatChem

One-pot one-step deracemization of amines using ω-transaminases

(2013) Giyoung Shin et al.   CHEMICAL COMMUNICATIONS

Concise Chemoenzymatic Three-Step Total Synthesis of Isosolenopsin through Medium Engineering

(2013) Robert C. Simon et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

ω-Transaminase-catalyzed asymmetric synthesis of unnatural amino acids using isopropylamine as an amino donor

(2013) Eul-Soo Park et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Amination of Tetralone and Chromanone Derivatives Employing ω-Transaminases

(2013) Desiree Pressnitz et al.   ACS Catalysis

Features and technical applications of ω-transaminases

(2012) M. Shaheer Malik et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

17β-Arylsulfonamides of 17β-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase

(2012) Yaser A. Mostafa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

(2012) Bo Wang et al.   CHEMICAL COMMUNICATIONS

CRTH2 Antagonist MK-7246: A Synthetic Evolution from Discovery through Development

(2012) Carmela Molinaro et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of a Dual Orexin Receptor Antagonist

(2012) Ian K. Mangion et al.   ORGANIC LETTERS

ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

(2012) Sam Mathew et al.   ACS Catalysis

Stereoselectivity of Four (R)-Selective Transaminases for the Asymmetric Amination of Ketones

(2011) Francesco G. Mutti et al.   ADVANCED SYNTHESIS & CATALYSIS

Steroid sulfatase inhibitors: Promising new tools for breast cancer therapy?

(2011) Jürgen Geisler et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of a Disordered Steroid Metabolome in the Elucidation of Sterol and Steroid Biosynthesis

(2011) Cedric H. L. Shackleton   LIPIDS

Efficient syntheses of 17-β-amino steroids

(2011) Scott D. Taylor et al.   STEROIDS

Steroid sulfatase inhibitors: A review covering the promising 2000–2010 decade

(2011) René Maltais et al.   STEROIDS

Chemoenzymatic asymmetric total synthesis of (S)-Rivastigmine using ω-transaminases

(2010) Michael Fuchs et al.   CHEMICAL COMMUNICATIONS

Transaminations with isopropyl amine: equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration

(2010) Karim Engelmark Cassimjee et al.   CHEMICAL COMMUNICATIONS

High-Yield Biocatalytic Amination Reactions in Organic Synthesis

(2010) John Ward et al.   CURRENT ORGANIC CHEMISTRY

Micro-scale process development of transaminase catalysed reactions

(2010) Matthew D. Truppo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Biocatalytic Routes to Optically Active Amines

(2009) Matthias Höhne et al.   ChemCatChem

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

(2009) Mark E. B. Smith et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases

(2009) Matthew D. Truppo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Stereoselectivity of an ω-transaminase-mediated amination of 1,3-dihydroxy-1-phenylpropane-2-one

(2009) Kirsty Smithies et al.   TETRAHEDRON-ASYMMETRY