Stereoselectivity of Four (R)-Selective Transaminases for the Asymmetric Amination of Ketones

Sitagliptin Manufacture: A Compelling Tale of Green Chemistry, Process Intensification, and Industrial Asymmetric Catalysis

(2011) Aman A. Desai   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Process considerations for the asymmetric synthesis of chiral amines using transaminases

(2011) Pär Tufvesson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Kinetic resolution of aromatic β-amino acids by ω-transaminase

(2011) Han-Seop Bea et al.   CHEMICAL COMMUNICATIONS

Straightforward preparation of biologically active 1-aryl- and 1-heteroarylpropan-2-amines in enantioenriched form

(2011) María Rodríguez-Mata et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-Pot Conversion of L-Threonine into L-Homoalanine: Biocatalytic Production of an Unnatural Amino Acid from a Natural One

(2010) Eulsoo Park et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Stereoselective Synthesis of Substituted Prolyl Peptides Using a Combination of Biocatalytic Desymmetrization and Multicomponent Reactions

(2010) Anass Znabet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Biocatalytic Oxidative Desymmetrization of Substituted Pyrrolidines

(2010) Valentin Köhler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases

(2010) Joo-Hyun Seo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Creating a Biocatalyst for the Production of an Optically Pure Sterically Hindered Amine

(2010) Francesco G. Mutti et al.   ChemCatChem

Reversed Enantiopreference of an ω-Transaminase by a Single-Point Mutation

(2010) Maria Svedendahl et al.   ChemCatChem

Transaminations with isopropyl amine: equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration

(2010) Karim Engelmark Cassimjee et al.   CHEMICAL COMMUNICATIONS

Deracemisation methods

(2010) Nicholas J Turner   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent progress in industrial biocatalysis

(2010) Bettina M Nestl et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

α, α -Dihydroxy Ketones and 2-Amino-1,3-diols: Synthetic and Process Strategies Using Biocatalysts

(2010) H. C. Hailes et al.   CURRENT ORGANIC CHEMISTRY

High-Yield Biocatalytic Amination Reactions in Organic Synthesis

(2010) John Ward et al.   CURRENT ORGANIC CHEMISTRY

Rational assignment of key motifs for function guides in silico enzyme identification

(2010) Matthias Höhne et al.   Nature Chemical Biology

ω-Transaminases as efficient biocatalysts to obtain novel chiral selenium-amine ligands for Pd-catalysis

(2010) Leandro H. Andrade et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Testing of microorganisms for ω-transaminase activity

(2010) Dorina Clay et al.   TETRAHEDRON-ASYMMETRY

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Biocatalytic asymmetric amination of carbonyl functional groups - a synthetic biology approach to organic chemistry

(2009) Dunming Zhu et al.   Biotechnology Journal

Biocatalytic Routes to Optically Active Amines

(2009) Matthias Höhne et al.   ChemCatChem

Synthesis of Optically Active Amines Employing Recombinant ω-Transaminases inE. coliCells

(2009) Dominik Koszelewski et al.   ChemCatChem

En Route to (S)-Selective Chemoenzymatic Dynamic Kinetic Resolution of Aliphatic Amines. One-Pot KR/Racemization/KR Sequence Leading to (S)-Amides

(2009) Lahssen El Blidi et al.   JOURNAL OF ORGANIC CHEMISTRY

New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity

(2009) Debra J. Wallace et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

(2009) Mark E. B. Smith et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases

(2009) Matthew D. Truppo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases

(2008) Dominik Koszelewski et al.   ADVANCED SYNTHESIS & CATALYSIS

Formal Asymmetric Biocatalytic Reductive Amination

(2008) Dominik Koszelewski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid screening and scale-up of transaminase catalysed reactions

(2008) Matthew D. Truppo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY