4.7 Article

A biocatalytic redox isomerisation

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 53, Pages 6630-6632

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31947k

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Funding

  1. Marie Curie ITN Biotrains [238531]

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A bi-enzymatic cascade for the redox-isomerisation of allylic alcohol is presented. Coupling of an alcohol dehydrogenase to an enoate reductase has been successfully applied in one pot for the isomerisation of an allylic alcohol to the corresponding ketone. Critical parameters for yield and selectivity have been investigated.

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