β-Sitosterol blocks the LEF-1-mediated Wnt/β-catenin pathway to inhibit proliferation of human colon cancer cells
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
β-Sitosterol blocks the LEF-1-mediated Wnt/β-catenin pathway to inhibit proliferation of human colon cancer cells
Authors
Keywords
-
Journal
CELLULAR SIGNALLING
Volume 104, Issue -, Pages 110585
Publisher
Elsevier BV
Online
2023-01-03
DOI
10.1016/j.cellsig.2022.110585
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma
- (2021) Zhiqiang Chen et al. Chinese Medicine
- LEF1 silencing sensitizes colorectal cancer cells to oxaliplatin, 5-FU, and irinotecan
- (2021) Elham Fakhr et al. BIOMEDICINE & PHARMACOTHERAPY
- LEF1 Enhances the Progression of Colonic Adenocarcinoma via Remodeling the Cell Motility Associated Structures
- (2021) Li Xiao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanism of Hedyotis Diffusa in the Treatment of Cervical Cancer
- (2021) Kai Qian et al. Frontiers in Pharmacology
- Colorectal cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- β-Sitosterol Reverses Multidrug Resistance via BCRP Suppression by Inhibiting the p53–MDM2 Interaction in Colorectal Cancer
- (2020) Ziyuan Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing
- (2020) Tao Yang et al. LIFE SCIENCES
- Quercetin Inhibits Lef1 and Resensitizes Docetaxel-Resistant Breast Cancer Cells
- (2020) Marta Prieto-Vila et al. MOLECULES
- Targeting β-Catenin Signaling by Natural Products for Cancer Prevention and Therapy
- (2020) Wen-Kai Yu et al. Frontiers in Pharmacology
- Cinobufagin Suppresses Melanoma Cell Growth by Inhibiting LEF1
- (2020) Geon-Hee Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cyclin D1 in Cancer: A Molecular Connection for Cell Cycle Control, Adhesion and Invasion in Tumor and Stroma
- (2020) Francesca Ida Montalto et al. Cells
- CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression
- (2019) Junhui Yu et al. Cell Death & Disease
- β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling
- (2019) Zhang-qi Cao et al. Frontiers in Pharmacology
- Wnt/PCP Signaling Contribution to Carcinoma Collective Cell Migration and Metastasis
- (2019) Kacey VanderVorst et al. CANCER RESEARCH
- The Protective Effect of Dietary Phytosterols on Cancer Risk: A Systematic Meta-Analysis
- (2019) Lu Jiang et al. Journal of Oncology
- SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation
- (2019) Vivien Freihen et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
- (2019) Fengzhi Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration
- (2019) Xiaobo Nie et al. Frontiers in Pharmacology
- Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation
- (2019) Yi-Heng Hao et al. Cell Communication and Signaling
- LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
- (2019) Jiayin Tang et al. Nature Communications
- Wnt signaling in development and tissue homeostasis
- (2018) Zachary Steinhart et al. DEVELOPMENT
- APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway
- (2018) Kenyi Saito-Diaz et al. DEVELOPMENTAL CELL
- Propolis wax nanostructured lipid carrier for delivery of β sitosterol: Effect of formulation variables on physicochemical properties
- (2018) Yasamin Soleimanian et al. FOOD CHEMISTRY
- High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions
- (2018) Dong Gu Lee et al. Journal of Ginseng Research
- Cellular and molecular mechanisms underlying planar cell polarity pathway contributions to cancer malignancy
- (2018) Kacey VanderVorst et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inhibition of LEF1-Mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness
- (2018) So-Yeon Park et al. CLINICAL CANCER RESEARCH
- Therapeutic strategies involving survivin inhibition in cancer
- (2018) David Martínez‐García et al. MEDICINAL RESEARCH REVIEWS
- Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
- (2017) Lu Zhang et al. JNCI-Journal of the National Cancer Institute
- Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
- (2017) Lu Zhang et al. JNCI-Journal of the National Cancer Institute
- Colorectal cancer statistics, 2014
- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- β-Sitosterol attenuates high-fat diet-induced intestinal inflammation in mice by inhibiting the binding of lipopolysaccharide to toll-like receptor 4 in the NF-κB pathway
- (2014) Kyung-Ah Kim et al. MOLECULAR NUTRITION & FOOD RESEARCH
- The transcription factor LEF-1 induces an epithelial–mesenchymal transition in MDCK cells independent of β-catenin
- (2013) Wakako Kobayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Increased LEF1 Expression and Decreased Notch2 Expression Are Strong Predictors of Poor Outcomes in Colorectal Cancer Patients
- (2013) Wen-Juan Wang et al. DISEASE MARKERS
- Transcriptional Amplification in Tumor Cells with Elevated c-Myc
- (2012) Charles Y. Lin et al. CELL
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- The many faces and functions of β-catenin
- (2012) Tomas Valenta et al. EMBO JOURNAL
- Frizzled and LRP5/6 Receptors for Wnt/ -Catenin Signaling
- (2012) B. T. MacDonald et al. Cold Spring Harbor Perspectives in Biology
- The -Catenin Destruction Complex
- (2012) J. L. Stamos et al. Cold Spring Harbor Perspectives in Biology
- Dysregulation of Wnt/β-Catenin Signaling in Gastrointestinal Cancers
- (2011) Bryan D. White et al. GASTROENTEROLOGY
- Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study
- (2010) Albert A Baskar et al. BMC Complementary and Alternative Medicine
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started