LEF1 silencing sensitizes colorectal cancer cells to oxaliplatin, 5-FU, and irinotecan

Quercetin Inhibits Lef1 and Resensitizes Docetaxel-Resistant Breast Cancer Cells

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Through oxaliplatin resistance induction in colorectal cancer cells, increasing ABCB1 level accompanies decreasing level of miR-302c-5p, miR-3664-5p and miR-129-5p

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miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy via transforming growth factor-β/Smad4 pathway

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MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition

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The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

(2016) Gabriele Romano et al.   Oncotarget

Silencing the wild-type and mutant K-ras increases the resistance to 5-flurouracil in HCT-116 as a colorectal cancer cell line

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Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance

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Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

(2015) Malin Wickström et al.   Nature Communications

TCF4 silencing sensitizes the colon cancer cell line to oxaliplatin as a common chemotherapeutic drug

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Inhibition of Transient Receptor Potential Channel 5 Reverses 5-Fluorouracil Resistance in Human Colorectal Cancer Cells

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Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

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Inhibition of Wnt/β-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma

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The balance between two isoforms of LEF-1 regulates colon carcinoma growth

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Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas

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Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death

(2011) Elisabet Ametller et al.   CANCER BIOLOGY & THERAPY

Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy

(2011) Emil Kendziorra et al.   CARCINOGENESIS

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Sixty Years of CA: A Cancer Journal for Clinicians

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Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: The roles of caspase-6 and p53

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Selective Suicide Gene Therapy of Colon Cancer Cell Lines Exploiting Fibroblast Growth Factor 18 Promoter

(2010) Ladan Teimoori-Toolabi et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer

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Stable reversal of multidrug resistance in colon cancer cells by RNA interference targeting the MDR1 gene

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