Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
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Title
Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
Authors
Keywords
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Journal
JNCI-Journal of the National Cancer Institute
Volume 109, Issue 8, Pages -
Publisher
Oxford University Press (OUP)
Online
2016-12-24
DOI
10.1093/jnci/djw332
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Note: Only part of the references are listed.- Genomic Landscape of Colorectal Mucosa and Adenomas
- (2016) E. Borras et al. Cancer Prevention Research
- Organoids as an in vitro model of human development and disease
- (2016) Aliya Fatehullah et al. NATURE CELL BIOLOGY
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- (2016) L. Zhang et al. Science Translational Medicine
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- (2015) Carlos T. Pineda et al. CELL
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- (2015) Ezgi Kunttas-Tatli et al. MOLECULAR BIOLOGY OF THE CELL
- Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment
- (2015) E. M. Alexandrova et al. NATURE
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids
- (2015) Mami Matano et al. NATURE MEDICINE
- A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction
- (2015) Mira I Pronobis et al. eLife
- Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras
- (2014) Alexander J. Byun et al. CANCER LETTERS
- 5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway
- (2014) Dipon Das et al. DNA REPAIR
- Can we safely target the WNT pathway?
- (2014) Michael Kahn NATURE REVIEWS DRUG DISCOVERY
- Apc and p53 interaction in DNA damage and genomic instability in hepatocytes
- (2014) V Méniel et al. ONCOGENE
- Understanding Phenotypic Variation in Rodent Models with Germline Apc Mutations
- (2013) M. Zeineldin et al. CANCER RESEARCH
- Animal models of colorectal cancer
- (2012) Robert L. Johnson et al. CANCER AND METASTASIS REVIEWS
- A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon Adenomas
- (2012) S. I. Nikolaev et al. CANCER RESEARCH
- Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems
- (2012) S. A. Nelson et al. Disease Models & Mechanisms
- Oxidatively damaged DNA and its repair in colon carcinogenesis
- (2012) Barbara Tudek et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- A Common Role for Various Human Truncated Adenomatous Polyposis Coli Isoforms in the Control of Beta-Catenin Activity and Cell Proliferation
- (2012) Shree Harsha Vijaya Chandra et al. PLoS One
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Mouse Models of Cancer
- (2011) Dong-Joo Cheon et al. Annual Review of Pathology-Mechanisms of Disease
- Assembly of the Base Excision Repair Complex on Abasic DNA and Role of Adenomatous Polyposis Coli on Its Functional Activity
- (2011) Aruna S. Jaiswal et al. BIOCHEMISTRY
- Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress
- (2011) Mariana G. Brocardo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Microsatellite Instability in Colorectal Cancer
- (2010) C. Richard Boland et al. GASTROENTEROLOGY
- Generation of a Transgenic Mouse for Colorectal Cancer Research with Intestinal Cre Expression Limited to the Large Intestine
- (2010) Y. Xue et al. MOLECULAR CANCER RESEARCH
- Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
- (2010) Curtis A Thorne et al. Nature Chemical Biology
- Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro
- (2009) Andres I. Roig et al. GASTROENTEROLOGY
- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
- (2009) Shih-Min A. Huang et al. NATURE
- Complete deletion of Apc results in severe polyposis in mice
- (2009) A F Cheung et al. ONCOGENE
- A novel function of adenomatous polyposis coli (APC) in regulating DNA repair
- (2008) Aruna S. Jaiswal et al. CANCER LETTERS
- Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli
- (2008) A P Kouzmenko et al. ONCOGENE
- APC and the three-hit hypothesis
- (2008) S Segditsas et al. ONCOGENE
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