Cancer hallmarks intersect with neuroscience in the tumor microenvironment

Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

(2022) De Huang et al.   NATURE CELL BIOLOGY

Hallmarks of Cancer: New Dimensions

(2022) Douglas Hanahan   Cancer Discovery

Neural Signaling in Cancer

(2022) Michael B. Keough et al.   Annual Review of Neuroscience

Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

(2022) Corina Anastasaki et al.   Nature Communications

Glioblastoma hijacks neuronal mechanisms for brain invasion

(2022) Varun Venkataramani et al.   CELL

Reprogrammed Schwann cells organize into dynamic tracks that promote pancreatic cancer invasion

(2022) Sylvie Deborde et al.   Cancer Discovery

Insights and opportunities at the crossroads of cancer and neuroscience

(2022) Chenchen Pan et al.   NATURE CELL BIOLOGY

Cancer Neuroscience: Evidence for a New Hallmark of Cancer

(2022) Moran Amit   Advanced Biology

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

(2022) Qiqun Zeng et al.   SCIENCE

Hallmarks of cancer—the new testament

(2021) Sasi S. Senga et al.   Open Biology

NF1 mutation drives neuronal activity-dependent initiation of optic glioma

(2021) Yuan Pan et al.   NATURE

Neurobiology of cancer: Definition, historical overview, and clinical implications

(2021) Boris Mravec   Cancer Medicine

Roadmap for the Emerging Field of Cancer Neuroscience

(2020) Michelle Monje et al.   CELL

Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth

(2020) Xiaofan Guo et al.   Nature Communications

Cancer-associated neurogenesis and nerve-cancer crosstalk

(2020) Deborah A Silverman et al.   CANCER RESEARCH

NLGN3 promotes neuroblastoma cell proliferation and growth through activating PI3K/AKT pathway

(2019) Zuoqing Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tumor Neurobiology and the War of Nerves in Cancer

(2019) Sam Faulkner et al.   Cancer Discovery

Electrical and synaptic integration of glioma into neural circuits

(2019) Humsa S. Venkatesh et al.   NATURE

Glutamatergic synaptic input to glioma cells drives brain tumour progression

(2019) Varun Venkataramani et al.   NATURE

Synaptic proximity enables NMDAR signalling to promote brain metastasis

(2019) Qiqun Zeng et al.   NATURE

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth

(2018) Leanne Li et al.   CANCER CELL

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer

(2018) Bernhard W. Renz et al.   CANCER CELL

Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer

(2018) Snider Desir et al.   Scientific Reports

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

(2017) Humsa S. Venkatesh et al.   NATURE

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

(2017) Ali H. Zahalka et al.   SCIENCE

The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells

(2017) Francesca Zalfa et al.   Cell Death & Disease

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

(2015) Humsa S. Venkatesh et al.   CELL

Brain tumour cells interconnect to a functional and resistant network

(2015) Matthias Osswald et al.   NATURE

Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion

(2013) Leanne Li et al.   CELL

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

(2013) Rossella Lucá et al.   EMBO Molecular Medicine

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL