Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
Authors
Keywords
-
Journal
NATURE CELL BIOLOGY
Volume 24, Issue 2, Pages 230-241
Publisher
Springer Science and Business Media LLC
Online
2022-02-11
DOI
10.1038/s41556-021-00820-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
- (2021) Baihao Zhang et al. NATURE
- The GABAB Receptor—Structure, Ligand Binding and Drug Development
- (2020) Linn Samira Mari Evenseth et al. MOLECULES
- GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner
- (2019) Shu-Heng Jiang et al. GUT
- Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
- (2019) Denarda Dangaj et al. CANCER CELL
- β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma
- (2019) Marina Ruiz de Galarreta et al. Cancer Discovery
- Neurotransmitters: emerging targets in cancer
- (2019) Shu-Heng Jiang et al. ONCOGENE
- Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy
- (2019) John-Michael Williford et al. Science Advances
- Capillary morphogenesis protein 2 is a novel prognostic biomarker and plays oncogenic roles in glioma
- (2018) Juan Tan et al. JOURNAL OF PATHOLOGY
- The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells
- (2018) Makoto Inoue et al. PLoS One
- GABA B R-Induced EGFR Transactivation Promotes Migration of Human Prostate Cancer Cells
- (2017) Shuai Xia et al. MOLECULAR PHARMACOLOGY
- GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC50and Basal Activity
- (2017) Gustav Akk et al. MOLECULAR PHARMACOLOGY
- Critical Role for CD103 + /CD141 + Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma
- (2016) Edward W. Roberts et al. CANCER CELL
- Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
- (2016) Hélène Salmon et al. IMMUNITY
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
- (2016) Kiranmai Gumireddy et al. Nature Communications
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression
- (2014) Regina Lin et al. JOURNAL OF CLINICAL INVESTIGATION
- Mass-spectrometry-based draft of the human proteome
- (2014) Mathias Wilhelm et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Systematic identification of signaling pathways with potential to confer anticancer drug resistance
- (2014) C. A. Martz et al. Science Signaling
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- Different Subtypes of GABA-A Receptors Are Expressed in Human, Mouse and Rat T Lymphocytes
- (2012) Suresh K. Mendu et al. PLoS One
- Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway
- (2010) Christophe Fuerer et al. PLoS One
- Inhibitory role for GABA in autoimmune inflammation
- (2010) R. Bhat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- GABA’s Control of Stem and Cancer Cell Proliferation in Adult Neural and Peripheral Niches
- (2009) Stephanie Z. Young et al. PHYSIOLOGY
- GABA, a natural immunomodulator of T lymphocytes
- (2008) Helen Bjurstöm et al. JOURNAL OF NEUROIMMUNOLOGY
- Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity
- (2008) K. Hildner et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started