Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-05-19
DOI
10.1038/s41467-022-30466-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing
- (2021) Jean-Philippe Brosseau et al. Acta Neuropathologica Communications
- NF1 mutation drives neuronal activity-dependent initiation of optic glioma
- (2021) Yuan Pan et al. NATURE
- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels as Drug Targets for Neurological Disorders
- (2020) Bina Santoro et al. Annual Review of Pharmacology and Toxicology
- PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis
- (2020) Kwanha Yu et al. NATURE
- Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
- (2020) Xiaofan Guo et al. Nature Communications
- Human iPSC-Derived Neurons and Cerebral Organoids Establish Differential Effects of Germline NF1 Gene Mutations
- (2020) Corina Anastasaki et al. Stem Cell Reports
- Temporal, spatial, and genetic constraints contribute to the patterning and penetrance of murine Neurofibromatosis-1 optic glioma
- (2020) Nicole M Brossier et al. NEURO-ONCOLOGY
- Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice
- (2020) Qays Kharouf et al. EPILEPSY RESEARCH
- Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins
- (2020) Juan Mo et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell–specific chemokine recruitment of T cells and microglia
- (2019) Xiaofan Guo et al. NEURO-ONCOLOGY
- Electrical and synaptic integration of glioma into neural circuits
- (2019) Humsa S. Venkatesh et al. NATURE
- Glutamatergic synaptic input to glioma cells drives brain tumour progression
- (2019) Varun Venkataramani et al. NATURE
- Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844–848
- (2018) Magdalena Koczkowska et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Athymic mice reveal a requirement for T-cell–microglia interactions in establishing a microenvironment supportive ofNf1low-grade glioma growth
- (2018) Yuan Pan et al. GENES & DEVELOPMENT
- Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis
- (2018) Chung-Ping Liao et al. JOURNAL OF CLINICAL INVESTIGATION
- STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma
- (2018) Jonathan S. Fletcher et al. ONCOGENE
- Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway
- (2018) Zhiguo Chen et al. Cancer Discovery
- Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma
- (2017) Humsa S. Venkatesh et al. NATURE
- Identification of diverse astrocyte populations and their malignant analogs
- (2017) Chia-Ching John Lin et al. NATURE NEUROSCIENCE
- Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
- (2017) Yuan Pan et al. Oncotarget
- NF1germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1
- (2016) Joseph A. Toonen et al. HUMAN MOLECULAR GENETICS
- Physical interaction between neurofibromin and serotonin 5-HT6receptor promotes receptor constitutive activity
- (2016) Wissem Deraredj Nadim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion
- (2015) Humsa S. Venkatesh et al. CELL
- Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning
- (2015) C. Anastasaki et al. HUMAN MOLECULAR GENETICS
- High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation
- (2015) Kitiwan Rojnueangnit et al. HUMAN MUTATION
- HCN Channels—Modulators of Cardiac and Neuronal Excitability
- (2015) Stefan Herrmann et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1
- (2015) A Omrani et al. MOLECULAR PSYCHIATRY
- RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth
- (2015) Anne C. Solga et al. NEOPLASIA
- Cells of Origin in the Embryonic Nerve Roots for NF1-Associated Plexiform Neurofibroma
- (2014) Zhiguo Chen et al. CANCER CELL
- p.Arg1809Cys substitution in neurofibromin is associated with a distinctive NF1 phenotype without neurofibromas
- (2014) Valentina Pinna et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy
- (2014) Susan L. Campbell et al. GLIA
- Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas
- (2014) Brigitte C. Widemann et al. PEDIATRIC BLOOD & CANCER
- Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition
- (2012) Carlos E. Prada et al. ACTA NEUROPATHOLOGICA
- Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems
- (2012) Fausto J. Rodriguez et al. ACTA NEUROPATHOLOGICA
- Reduced microglial CX3CR1 expression delays neurofibromatosis-1 glioma formation
- (2012) Winnie W. Pong et al. ANNALS OF NEUROLOGY
- Innate Neural Stem Cell Heterogeneity Determines the Patterning of Glioma Formation in Children
- (2012) Da Yong Lee et al. CANCER CELL
- Human glioma cells induce hyperexcitability in cortical networks
- (2012) Susan L. Campbell et al. EPILEPSIA
- Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways
- (2012) Béatrice Vallée et al. PLoS One
- Interaction of tumor cells with the microenvironment
- (2011) Hendrik Ungefroren et al. Cell Communication and Signaling
- Valosin-containing protein and neurofibromin interact to regulate dendritic spine density
- (2011) Hsiao-Fang Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Glutamate release by primary brain tumors induces epileptic activity
- (2011) Susan C Buckingham et al. NATURE MEDICINE
- Ivabradine: from molecular basis to clinical effectiveness
- (2010) Graziano Riccioni ADVANCES IN THERAPY
- Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service
- (2010) D.G. Evans et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Nf1−/− Schwann Cell-Conditioned Medium Modulates Mast Cell Degranulation by c-Kit-Mediated Hyperactivation of Phosphatidylinositol 3-Kinase
- (2010) Shi Chen et al. AMERICAN JOURNAL OF PATHOLOGY
- Clinical and genetic aspects of neurofibromatosis 1
- (2010) Kimberly Jett et al. GENETICS IN MEDICINE
- Cell of Origin and Microenvironment Contribution for NF1-Associated Dermal Neurofibromas
- (2009) Lu Q. Le et al. Cell Stem Cell
- Inflammation-induced increase in hyperpolarization-activated, cyclic nucleotide-gated channel protein in trigeminal ganglion neurons and the effect of buprenorphine
- (2009) H.-J. Cho et al. NEUROSCIENCE
- Increased c-Jun-NH2-Kinase Signaling in Neurofibromatosis-1 Heterozygous Microglia Drives Microglia Activation and Promotes Optic Glioma Proliferation
- (2008) G. C. Daginakatte et al. CANCER RESEARCH
- Preclinical Cancer Therapy in a Mouse Model of Neurofibromatosis-1 Optic Glioma
- (2008) B. Hegedus et al. CANCER RESEARCH
- Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/−- and c-kit-Dependent Bone Marrow
- (2008) Feng-Chun Yang et al. CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started