Hallmarks of cancer—the new testament

Production of an anti-angiogenic factor sFLT1 is suppressed via promoter hypermethylation of FLT1 gene in choriocarcinoma cells

(2020) Tadashi Sasagawa et al.   BMC CANCER

Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice

(2020) Giuseppina D'Alessandro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

(2020) Cayetano Pleguezuelos-Manzano et al.   NATURE

Compression-induced dedifferentiation of adipocytes promotes tumor progression

(2020) Yiwei Li et al.   Science Advances

Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis

(2020) Jun Nishida et al.   NATURE CELL BIOLOGY

Gain Fat—Lose Metastasis: Converting Invasive Breast Cancer Cells into Adipocytes Inhibits Cancer Metastasis

(2019) Dana Ishay-Ronen et al.   CANCER CELL

Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

(2019) Sabrina Chriett et al.   Scientific Reports

Environmental Risk Factors for Inflammatory Bowel Diseases: an Umbrella Review of Meta-analyses

(2019) Daniele Piovani et al.   GASTROENTEROLOGY

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

(2019) Erick Riquelme et al.   CELL

Electrical and synaptic integration of glioma into neural circuits

(2019) Humsa S. Venkatesh et al.   NATURE

Glutamatergic synaptic input to glioma cells drives brain tumour progression

(2019) Varun Venkataramani et al.   NATURE

Synaptic proximity enables NMDAR signalling to promote brain metastasis

(2019) Qiqun Zeng et al.   NATURE

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

(2019) Berk Aykut et al.   NATURE

The landscape of somatic mutation in normal colorectal epithelial cells

(2019) Henry Lee-Six et al.   NATURE

Enumeration of Escherichia coli in Probiotic Products

(2019) Camille Zimmer et al.   Microorganisms

Seizures and Tumor Progression in Glioma Patients with Uncontrollable Epilepsy Treated with Perampanel

(2018) SHUICHI IZUMOTO et al.   ANTICANCER RESEARCH

Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

(2018) Jennifer Tsoi et al.   CANCER CELL

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer

(2018) Bernhard W. Renz et al.   CANCER CELL

Helicobacter pylori infection and demyelinating disease of the central nervous system

(2018) Jun-ichi Kira et al.   JOURNAL OF NEUROIMMUNOLOGY

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

(2018) Maria Maryanovich et al.   NATURE MEDICINE

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells

(2018) Nadège Bossuet-Greif et al.   mBio

Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women

(2018) Paweł Łaniewski et al.   Scientific Reports

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

(2018) David Tyssen et al.   mSphere

Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer

(2018) Silvia Halim et al.   BRITISH JOURNAL OF CANCER

CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic

(2017) A D Marshall et al.   ONCOGENE

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

(2017) Ali H. Zahalka et al.   SCIENCE

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model

(2017) Lars Ivo Partecke et al.   Oncotarget

Epigenetic Switch between SOX2 and SOX9 Regulates Cancer Cell Plasticity

(2016) Sheng-Chieh Lin et al.   CANCER RESEARCH

Pathobiology of Helicobacter pylori–Induced Gastric Cancer

(2016) Manuel Amieva et al.   GASTROENTEROLOGY

The Vaginal Microbiome: Current Understanding and Future Directions

(2016) David H. Martin et al.   JOURNAL OF INFECTIOUS DISEASES

Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer

(2016) Qing Chen et al.   NATURE

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

(2016) Olga A Guryanova et al.   NATURE MEDICINE

Targeting EZH2 in cancer

(2016) Kimberly H Kim et al.   NATURE MEDICINE

Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade

(2016) Lars Ivo Partecke et al.   PANCREATOLOGY

NLRC5/MHC class I transactivator is a target for immune evasion in cancer

(2016) Sayuri Yoshihama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer

(2016) Jami L. Saloman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of proto-oncogenes by disruption of chromosome neighborhoods

(2016) D. Hnisz et al.   SCIENCE

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

(2016) C. K. Kaufman et al.   SCIENCE

Association ofFusobacterium nucleatumwith immunity and molecular alterations in colorectal cancer

(2016) Katsuhiko Nosho   WORLD JOURNAL OF GASTROENTEROLOGY

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

(2016) Caroline P. Le et al.   Nature Communications

Autonomic nervous infiltration positively correlates with pathological risk grading and poor prognosis in patients with lung adenocarcinoma

(2016) Jing-Xin Shao et al.   Thoracic Cancer

Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

(2016) Aditi A. Bapat et al.   PLoS One

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

(2015) Samantha J. Mentch et al.   Cell Metabolism

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

(2015) M. Dal Molin et al.   CLINICAL CANCER RESEARCH

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

(2015) Lawrence N. Kwong et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative analysis of CDKN2A methylation, mRNA, and p16INK4a protein expression in children and adolescents with Burkitt lymphoma: Biological and clinical implications

(2015) Marcela Cristina S. Robaina et al.   LEUKEMIA RESEARCH

Insulator dysfunction and oncogene activation in IDH mutant gliomas

(2015) William A. Flavahan et al.   NATURE

The colibactin warhead crosslinks DNA

(2015) Maria I. Vizcaino et al.   Nature Chemistry

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity

(2015) A. Mitra et al.   Scientific Reports

ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

(2015) Mattheus C.B. Wielenga et al.   Cell Reports

ProNGF Correlates with Gleason Score and Is a Potential Driver of Nerve Infiltration in Prostate Cancer

(2014) Jay Pundavela et al.   AMERICAN JOURNAL OF PATHOLOGY

The Impact of Neural Invasion Severity in Gastrointestinal Malignancies

(2014) Florian Liebl et al.   ANNALS OF SURGERY

Helicobacter pylori CagA and Gastric Cancer: A Paradigm for Hit-and-Run Carcinogenesis

(2014) Masanori Hatakeyama   Cell Host & Microbe

Chromatin features and the epigenetic regulation of pluripotency states in ESCs

(2014) W.-W. Tee et al.   DEVELOPMENT

High-frequencyp16INK4Apromoter methylation is associated with histone methyltransferase SETDB1 expression in sporadic cutaneous melanoma

(2014) Maria Kostaki et al.   EXPERIMENTAL DERMATOLOGY

Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis

(2014) Elizabeth C. Wick et al.   INFLAMMATORY BOWEL DISEASES

Control of lymphocyte egress from lymph nodes through β2-adrenergic receptors

(2014) Akiko Nakai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Investigation of Schwann Cells at Neoplastic Cell Sites Before the Onset of Cancer Invasion

(2014) Ihsan Ekin Demir et al.   JNCI-Journal of the National Cancer Institute

Nerve Fibers in Breast Cancer Tissues Indicate Aggressive Tumor Progression

(2014) Di Huang et al.   MEDICINE

Role of vacuolating cytotoxin VacA and cytotoxin-associated antigen CagA of Helicobacter pylori in the progression of gastric cancer

(2014) Mi-Ran Ki et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

[18F](2S,4S)-4-(3-Fluoropropyl)glutamine as a Tumor Imaging Agent

(2014) Zehui Wu et al.   MOLECULAR PHARMACEUTICS

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

(2014) Liran I. Shlush et al.   NATURE

Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms

(2014) Lorena Arranz et al.   NATURE

Denervation suppresses gastric tumorigenesis

(2014) C.-M. Zhao et al.   Science Translational Medicine

Ménage à trois: an evolutionary interplay between human papillomavirus, a tumor, and a woman

(2014) Natalia Shulzhenko et al.   TRENDS IN MICROBIOLOGY

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

(2014) Judith Müller et al.   Nature Communications

Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism and Folate Intake in Esophageal Squamous Cell Carcinoma

(2013) Jing Chen et al.   Asian Pacific Journal of Cancer Prevention

Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion

(2013) Leanne Li et al.   CELL

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

(2013) Lin Cheng et al.   CELL

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate

(2013) Abby Sarkar et al.   Cell Stem Cell

Infection and Cancer: Revaluation of the Hygiene Hypothesis

(2013) K. Oikonomopoulou et al.   CLINICAL CANCER RESEARCH

Cometabolism of Microbes and Host: Implications for Drug Metabolism and Drug-Induced Toxicity

(2013) H Li et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bacteroides fragilis enterotoxin upregulates lipocalin-2 expression in intestinal epithelial cells

(2013) Do Young Yoo et al.   LABORATORY INVESTIGATION

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

(2013) Kathryn Blaschke et al.   NATURE

Direct reprogramming by oncogenic Ras and Myc

(2013) I. Ischenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Helicobacter pyloriinduces promoter methylation of E-cadherin via interleukin-1β activation of nitric oxide production in gastric cancer cells

(2012) Fung-Yu Huang et al.   CANCER

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

(2012) Janel L. Kopp et al.   CANCER CELL

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

(2012) Sarah Schwitalla et al.   CELL

Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

(2012) Catherine de Martel et al.   LANCET ONCOLOGY

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

(2012) Sevin Turcan et al.   NATURE

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

(2012) Jiekai Chen et al.   NATURE GENETICS

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

(2012) Sakari Vanharanta et al.   NATURE MEDICINE

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

(2012) D. Heja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implanted adipose progenitor cells as physicochemical regulators of breast cancer

(2012) E. M. Chandler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Synergy in biofilm formation between Fusobacterium nucleatum and Prevotella species

(2011) Tamaki Okuda et al.   ANAEROBE

Neurogenesis in colorectal cancer is a marker of aggressive tumor behavior and poor outcomes

(2011) Daniel Albo et al.   CANCER

Infection, immunoregulation, and cancer

(2011) Graham A. W. Rook et al.   IMMUNOLOGICAL REVIEWS

Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

(2011) Andrew D Gaudet et al.   Journal of Neuroinflammation

Aberrant Promoter CpG Methylation Is a Mechanism for Impaired PHD3 Expression in a Diverse Set of Malignant Cells

(2011) Trenton L. Place et al.   PLoS One

Towards the Human Colorectal Cancer Microbiome

(2011) Julian R. Marchesi et al.   PLoS One

Transdifferentiation of glioblastoma cells into vascular endothelial cells

(2011) Y. Soda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal action on the developing blood vessel pattern

(2011) Jennifer M. James et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The role of acidification in the inhibition of Neisseria gonorrhoeae by vaginal lactobacilli during anaerobic growth

(2011) Michelle A Graver et al.   Annals of Clinical Microbiology and Antimicrobials

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

(2010) N. Riggi et al.   GENES & DEVELOPMENT

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis

(2010) M Tessema et al.   ONCOGENE

Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis

(2010) Sharon Perry et al.   PLoS One

Hypomethylation of repeated DNA sequences in cancer

(2010) Jason P Ross et al.   Epigenomics

The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

(2010) Eric P. Skaar   PLoS Pathogens

Breast cancer brain metastases: differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT)

(2009) A. Niwinska et al.   ANNALS OF ONCOLOGY

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

Epigenetic Silencing of Death Receptor 4 Mediates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Resistance in Gliomas

(2009) A. Elias et al.   CLINICAL CANCER RESEARCH

VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors

(2009) A M Schmitt et al.   ENDOCRINE-RELATED CANCER

E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

(2009) Johannes von Burstin et al.   GASTROENTEROLOGY

Slackia equolifaciens sp. nov., a human intestinal bacterium capable of producing equol

(2009) J.-S. Jin et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Helicobacter pyloriCagA Causes Mitotic Impairment and Induces Chromosomal Instability

(2009) Mayumi Umeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic and Proteomic Analysis Reveals a Threshold Level of MYC Required for Tumor Maintenance

(2008) C. M. Shachaf et al.   CANCER RESEARCH

Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor

(2008) N. Herranz et al.   MOLECULAR AND CELLULAR BIOLOGY

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Concerning the Origin of Malignant Tumours by Theodor Boveri. Translated and annotated by Henry Harris

(2007) T. Boveri   JOURNAL OF CELL SCIENCE