Synaptic Terminal Density Early in the Course of Schizophrenia: an in vivo UCB-J Positron Emission Tomographic Imaging Study of Synaptic Vesicle Glycoprotein 2A (SV2A)

The synaptic hypothesis of schizophrenia version III: a master mechanism

(2023) Oliver D. Howes et al.   MOLECULAR PSYCHIATRY

Incomplete hippocampal inversion: a neurodevelopmental mechanism for hippocampal shape deformation in schizophrenia

(2022) Maxwell J. Roeske et al.   BIOLOGICAL PSYCHIATRY

Integrating the neurodevelopmental and dopamine hypotheses of schizophrenia and the role of cortical excitation-inhibition balance.

(2022) Oliver D. Howes et al.   BIOLOGICAL PSYCHIATRY

In vivo evidence of lower synaptic vesicle density in schizophrenia

(2021) Rajiv Radhakrishnan et al.   MOLECULAR PSYCHIATRY

The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study

(2021) Ellis Chika Onwordi et al.   Translational Psychiatry

Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring

(2021) Filippo Mirabella et al.   IMMUNITY

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

(2020) Ellis Chika Onwordi et al.   Nature Communications

Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning

(2019) Carl M. Sellgren et al.   NATURE NEUROSCIENCE

Antipsychotics: Mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology

(2019) Stephen J. Kaar et al.   NEUROPHARMACOLOGY

Assessment of a white matter reference region for 11C-UCB-J PET quantification

(2019) Samantha Rossano et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Chronic social defeat stress induces sustained synaptic structural changes in the prefrontal cortex and amygdala

(2019) L. Colyn et al.   BEHAVIOURAL BRAIN RESEARCH

Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention

(2018) J A Lieberman et al.   MOLECULAR PSYCHIATRY

Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures

(2018) Emanuele Felice Osimo et al.   MOLECULAR PSYCHIATRY

Dysconnectivity of Large-Scale Functional Networks in Early Psychosis: A Meta-analysis

(2018) Aisling O’Neill et al.   SCHIZOPHRENIA BULLETIN

Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

(2017) Sjoerd J Finnema et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Heterogeneity and Homogeneity of Regional Brain Structure in Schizophrenia

(2017) Stefan P. Brugger et al.   JAMA Psychiatry

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization

(2017) O D Howes et al.   Translational Psychiatry

Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model

(2016) F. Papaleo et al.   JOURNAL OF NEUROSCIENCE

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

(2016) Marilia A. Calcia et al.   PSYCHOPHARMACOLOGY

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Dendritic spine alterations in schizophrenia

(2015) Caitlin E. Moyer et al.   NEUROSCIENCE LETTERS

Prenatal Infection Affects the Neuronal Architecture and Cognitive Function in Adult Mice

(2014) Wai-Yu Li et al.   DEVELOPMENTAL NEUROSCIENCE

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Reappraising the long-term course and outcome of psychotic disorders: the AESOP-10 study

(2014) C. Morgan et al.   PSYCHOLOGICAL MEDICINE

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies

(2012) A Vita et al.   Translational Psychiatry

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia

(2011) Daniel J. Lodge et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Hippocampal Formation in Schizophrenia

(2010) Carol A. Tamminga et al.   AMERICAN JOURNAL OF PSYCHIATRY

Cortical Thickness and Subcortical Volumes in Schizophrenia and Bipolar Disorder

(2010) Lars M. Rimol et al.   BIOLOGICAL PSYCHIATRY

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy

(2010) Andri C. Tziortzi et al.   NEUROIMAGE

Progressive Structural Brain Changes During Development of Psychosis

(2010) Tim B. Ziermans et al.   SCHIZOPHRENIA BULLETIN