Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

Enabling Efficient Positron Emission Tomography (PET) Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) with a Robust and One-Step Radiosynthesis of a Highly Potent 18F-Labeled Ligand ([18F]UCB-H)

(2016) Corentin Warnier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

[11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A

(2016) Sergio Estrada et al.   NUCLEAR MEDICINE AND BIOLOGY

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

(2015) Adam C. Kaufman et al.   ANNALS OF NEUROLOGY

Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action

(2015) Jean-Marie Nicolas et al.   EPILEPSIA

Test–retest reproducibility of the metabotropic glutamate receptor 5 ligand [18F]FPEB with bolus plus constant infusion in humans

(2015) Eunkyung Park et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Test-Retest Reproducibility of Binding Parameters in Humans with 11C-LY2795050, an Antagonist PET Radiotracer for the   Opioid Receptor

(2015) M. Naganawa et al.   JOURNAL OF NUCLEAR MEDICINE

Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study

(2015) F. Bretin et al.   MOLECULAR IMAGING AND BIOLOGY

Parametric Imaging and Test-Retest Variability of 11C-(+)-PHNO Binding to D2/D3 Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner

(2014) J.-D. Gallezot et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

(2014) G. I. Warnock et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand18F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys

(2014) Jean-Dominique Gallezot et al.   SYNAPSE

Radiosynthesis of 11C-Levetiracetam: A Potential Marker for PET Imaging of SV2A Expression

(2014) Hancheng Cai et al.   ACS Medicinal Chemistry Letters

Synaptic vesicle protein 2A: basic facts and role in synaptic function

(2013) Julieta Griselda Mendoza-Torreblanca et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Longitudinal Amyloid Imaging Using 11C-PiB: Methodologic Considerations

(2013) B. N. M. van Berckel et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of motion correction methods in human brain PET imaging-A simulation study based on human motion data

(2013) Xiao Jin et al.   MEDICAL PHYSICS

Preclinical radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H

(2013) Florian Bretin et al.   EJNMMI Research

Protein Quantification at the Single Vesicle Level Reveals That a Subset of Synaptic Vesicle Proteins Are Trafficked with High Precision

(2011) S. A. Mutch et al.   JOURNAL OF NEUROSCIENCE

SV2 regulates neurotransmitter release via multiple mechanisms

(2010) Amy Nowack et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Down-regulation Synaptic Vesicle Protein 2A in the Anterior Temporal Neocortex of Patients with Intractable Epilepsy

(2009) Guibo Feng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy

(2008) Erwin A. van Vliet et al.   EPILEPSIA