DTX3L induced NLRP3 ubiquitination inhibit R28 cell pyroptosis in OGD/R injury

Insight into Crosstalk Between Mitophagy and Apoptosis/Necroptosis: Mechanisms and Clinical Applications in Ischemic Stroke

(2022) Yan-di Yang et al.   Current Medical Science

PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons

(2022) Qi Zhang et al.   Neural Regeneration Research

The role of E3 ubiquitin ligases in the development and progression of glioblastoma

(2021) Luke M. Humphreys et al.   CELL DEATH AND DIFFERENTIATION

Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities

(2021) Zhu Liang et al.   Cell Communication and Signaling

Receptors, Channel Proteins, and Enzymes Involved in Microglia-mediated Neuroinflammation and Treatments by Targeting Microglia in Ischemic Stroke

(2021) Kun Hou et al.   NEUROSCIENCE

Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine

(2021) Lenka Koklesova et al.   EPMA Journal

c-FLIP regulates pyroptosis in retinal neurons following oxygen-glucose deprivation/recovery via a GSDMD-mediated pathway

(2021) Yanxia Huang et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

An update on the regulatory mechanisms of NLRP3 inflammasome activation

(2021) Seungwha Paik et al.   Cellular & Molecular Immunology

Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats

(2021) Chaoqun Nie et al.   LIFE SCIENCES

Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

(2021) Xiao He et al.   PHARMACOLOGICAL RESEARCH

Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies

(2021) Qi Zhang et al.   Neural Regeneration Research

Pyroptosis: A New Insight Into Eye Disease Therapy

(2021) Yun Zhang et al.   Frontiers in Pharmacology

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia

(2020) Juan Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Necroptosis in renal ischemia/reperfusion injury: A major mode of cell death?

(2020) Wu Jun et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Autophagy and post-ischemic conditioning in retinal ischemia

(2020) Biji Mathew et al.   Autophagy

Neuroprotective Strategies for Retinal Ganglion Cell Degeneration: Current Status and Challenges Ahead

(2020) Raquel Boia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RSK3 mediates necroptosis by regulating phosphorylation of RIP3 in rat retinal ganglion cells

(2020) Mi Wang et al.   JOURNAL OF ANATOMY

TRIM31 inhibits NLRP3 inflammasome and pyroptosis of retinal pigment epithelial cells through ubiquitination of NLRP3

(2020) Peirong Huang et al.   CELL BIOLOGY INTERNATIONAL

Inflammasomes and Proteostasis Novel Molecular Mechanisms Associated With Atrial Fibrillation

(2020) Na Li et al.   CIRCULATION RESEARCH

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

(2020) Chatrin Chatrin et al.   Science Advances

The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome

(2020) R. Alex Wu et al.   TRENDS IN CELL BIOLOGY

Cullin1 binds and promotes NLRP3 ubiquitination to repress systematic inflammasome activation

(2019) Pin Wan et al.   FASEB JOURNAL

Histone acetylation and DNA methylation in ischemia/reperfusion injury

(2019) Jinhua Tang et al.   CLINICAL SCIENCE

Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion

(2019) Biji Mathew et al.   BIOMATERIALS

Control of the inflammasome by the ubiquitin system

(2019) Gloria Lopez‐Castejon   FEBS Journal

Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression

(2018) Zhen Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway

(2018) Shuchao Wang et al.   Frontiers in Cellular Neuroscience

Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons

(2018) Shuchao Wang et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Pyroptosis versus necroptosis: similarities, differences, and crosstalk

(2018) Daniel Frank et al.   CELL DEATH AND DIFFERENTIATION

Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition

(2017) Paul J. Baker et al.   PHYSIOLOGICAL REVIEWS

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

(2016) Marianne R. Spalinger et al.   JOURNAL OF CLINICAL INVESTIGATION

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

(2016) Małgorzata Nita et al.   Oxidative Medicine and Cellular Longevity

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

(2016) Robin A. Aglietti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

(2016) Hui Song et al.   Nature Communications

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2E3 Ligase

(2015) SeungHye Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

(2015) Wei Chi et al.   Journal of Neuroinflammation

Erythropoietin Exerts a Neuroprotective Function Against Glutamate Neurotoxicity in Experimental Diabetic Retina

(2014) L. Gu et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

New insights into ubiquitin E3 ligase mechanism

(2014) Christopher E Berndsen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ubiquitin–Proteasome System in Retinal Health and Disease

(2013) Laura Campello et al.   MOLECULAR NEUROBIOLOGY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity

(2012) Bénédicte F. Py et al.   MOLECULAR CELL

HMGB1 in Development and Diseases of the Central Nervous System

(2012) Ping Fang et al.   MOLECULAR NEUROBIOLOGY

Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

(2009) N. Shabek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasomes: guardians of cytosolic sanctity

(2008) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS