Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention

(2020) Alena Liskova et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Plasma circular RNA hsa_circ_0001445 and coronary artery disease: Performance as a biomarker

(2020) David Vilades et al.   FASEB JOURNAL

Oxidative Stress and Antioxidant Status in High-Risk Prostate Cancer Subjects

(2020) Sanjeev Shukla et al.   Diagnostics

Mitochondrial function in immune cells in health and disease

(2020) M.M. Faas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Blood markers of oxidative stress are strongly associated with poorer prognosis in colorectal cancer patients

(2020) Daniel Boakye et al.   INTERNATIONAL JOURNAL OF CANCER

Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses

(2020) Peter Kubatka et al.   MOLECULES

Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: A review

(2020) Milad Ashrafizadeh et al.   PHYTOTHERAPY RESEARCH

Microtubule-associated protein tau (MAPT) promotes bicalutamide resistance and is associated with survival in prostate cancer

(2020) Yohei Sekino et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Modeling Parkinson’s Disease With the Alpha-Synuclein Protein

(2020) Mónica Gómez-Benito et al.   Frontiers in Pharmacology

Covid-19 pandemic by the “real-time” monitoring: the Tunisian case and lessons for global epidemics in the context of 3PM strategies

(2020) Lotfi Chaari et al.   EPMA Journal

Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine

(2020) Lenka Koklesova et al.   EPMA Journal

Functional imaging of mitochondria in retinal diseases using flavoprotein fluorescence

(2020) Andrew X. Chen et al.   EYE

Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions

(2020) Radek Kucera et al.   EPMA Journal

Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism

(2020) Marek Samec et al.   EPMA Journal

Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies: unsupervised machine learning and 3 PM recommendations

(2020) Elisha Goldstein et al.   EPMA Journal

Mitochondria and Parkinson’s Disease: Clinical, Molecular, and Translational Aspects

(2020) Max Borsche et al.   Journal of Parkinsons Disease

Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back

(2020) Lenka Koklesova et al.   Cancers

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

(2020) Peter Kubatka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Carotenoids in Cancer Metastasis—Status Quo and Outlook

(2020) Lenka Koklesova et al.   Biomolecules

Risks associated with the stroke predisposition at young age: facts and hypotheses in light of individualized predictive and preventive approach

(2019) Jiri Polivka et al.   EPMA Journal

Vaginal dryness: individualised patient profiles, risks and mitigating measures

(2019) Vadym Goncharenko et al.   EPMA Journal

Lymphoproliferation Impairment and Oxidative Stress in Blood Cells from Early Parkinson’s Disease Patients

(2019) Carmen Vida et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Common risk factors for heart failure and cancer

(2019) Wouter C Meijers et al.   CARDIOVASCULAR RESEARCH

Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma in Vivo and in Vitro

(2019) Kubatka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondria in Neuroprotection by Phytochemicals: Bioactive Polyphenols Modulate Mitochondrial Apoptosis System, Function and Structure

(2019) Makoto Naoi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease

(2019) Laiyuan Wang et al.   ATHEROSCLEROSIS

Effects of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer’s disease: a randomised, double-blind, placebo-controlled trial

(2019) Jingya Jia et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The Warburg Effect, Lactate, and Nearly a Century of Trying to Cure Cancer

(2019) Netanya Y. Spencer et al.   SEMINARS IN NEPHROLOGY

Mitochondria in Health and Disease

(2019) Sarah J. Annesley et al.   Cells

Association between Parkinson’s Disease and Risk of Cancer: A PRISMA-compliant Meta-analysis

(2019) Pengcheng Zhang et al.   ACS Chemical Neuroscience

Parkinson disease

(2019) R. Balestrino et al.   EUROPEAN JOURNAL OF NEUROLOGY

Resveratrol targeting the Wnt signaling pathway: A focus on therapeutic activities

(2019) Milad Ashrafizadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MULTIOMIC PATTERNS IN BODY FLUIDS: TECHNOLOGICAL CHALLENGE WITH A GREAT POTENTIAL TO IMPLEMENT THE ADVANCED PARADIGM OF 3P MEDICINE

(2019) Christopher Gerner et al.   MASS SPECTROMETRY REVIEWS

Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging

(2019) Ne N. Wu et al.   Oxidative Medicine and Cellular Longevity

Stroke among cancer patients

(2019) Nicholas G. Zaorsky et al.   Nature Communications

Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

(2019) Shehua Qian et al.   EPMA Journal

Oxidative Damage of DNA as Early Marker of Alzheimer’s Disease

(2019) Carmen Peña-Bautista et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alzheimer’s and Parkinson’s Diseases and the Risk of Cancer: A Cohort Study

(2019) Anne G. Ording et al.   JOURNAL OF ALZHEIMERS DISEASE

Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology

(2019) Jack O. Garnham et al.   Journal of Cachexia Sarcopenia and Muscle

The genetic architecture of mitochondrial dysfunction in Parkinson’s disease

(2018) S. B. Larsen et al.   CELL AND TISSUE RESEARCH

Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer’s Disease

(2018) Carola Stockburger et al.   JOURNAL OF ALZHEIMERS DISEASE

Die Schlüsselrolle der Multiomics in Prädiktion, Prävention und personalisierter Behandlung vom Glaukom

(2018) Olga Golubnitschaja   KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE

Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration

(2018) María J. Pérez et al.   Frontiers in Neuroscience

Mitochondrial HTRA2 Plays a Positive, Protective Role in Dictyostelium discoideum but Is Cytotoxic When Overexpressed

(2018) Suwei Chen et al.   Genes

High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure

(2018) Cheng-Hsien Chou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Association between Cancer and Alzheimer's Disease: Systematic Review and Meta-Analysis

(2018) Ling-Li Ma et al.   JOURNAL OF ALZHEIMERS DISEASE

The role of mitochondria in aging

(2018) Ji Yong Jang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial dysfunction in pathophysiology of heart failure

(2018) Bo Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Reappraisal of Ischemic Heart Disease

(2018) Juan-Carlos Kaski et al.   CIRCULATION

Overexpression of heat shock protein HSP90AA1 and translocase of the outer mitochondrial membrane TOM34 in HCV-induced hepatocellular carcinoma: A pilot study

(2018) Eman A. Toraih et al.   CLINICAL BIOCHEMISTRY

Aerobic exercise reduces triglycerides by targeting apolipoprotein C3 in patients with coronary heart disease

(2018) Yating Wang et al.   CLINICAL CARDIOLOGY

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

(2018) Amy M. Smith et al.   MOVEMENT DISORDERS

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease

(2018) Maria Nguyen et al.   TRENDS IN NEUROSCIENCES

State of Play in Alzheimer’s Disease Genetics

(2017) Jin-Bao Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

(2017) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tumour heterogeneity and resistance to cancer therapies

(2017) Ibiayi Dagogo-Jack et al.   Nature Reviews Clinical Oncology

Elevated mitochondrial DNA copy numbers in pediatric acute lymphoblastic leukemia: A potential biomarker for predicting inferior survival

(2017) Ayushi Jain et al.   PEDIATRIC BLOOD & CANCER

A multivariate predictive modeling approach reveals a novel CSF peptide signature for both Alzheimer's Disease state classification and for predicting future disease progression

(2017) Daniel A. Llano et al.   PLoS One

Alzheimer’s disease: as it was in the beginning

(2017) Stanislav Kozlov et al.   REVIEWS IN THE NEUROSCIENCES

Genetics and genomics of dilated cardiomyopathy and systolic heart failure

(2017) Upasana Tayal et al.   Genome Medicine

Mitochondria and α-Synuclein: Friends or Foes in the Pathogenesis of Parkinson’s Disease?

(2017) Gaia Faustini et al.   Genes

Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer

(2017) Flora Guerra et al.   Frontiers in Oncology

Shared Risk Factors in Cardiovascular Disease and Cancer

(2016) Ryan J. Koene et al.   CIRCULATION

Relationship between chronic disturbance of 2,3-diphosphoglycerate metabolism in erythrocytes and Alzheimer disease

(2016) Elena A. Kosenko et al.   CNS & Neurological Disorders-Drug Targets

Role of mitochondrial dysfunction in cancer progression

(2016) Chia-Chi Hsu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Protective effects of physical exercise on MDMA-induced cognitive and mitochondrial impairment

(2016) Ghorban Taghizadeh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial involvement in myocyte death and heart failure

(2016) Michael J. Goldenthal   HEART FAILURE REVIEWS

Maximal oxygen uptake is proportional to muscle fiber oxidative capacity, from chronic heart failure patients to professional cyclists

(2016) Stephan van der Zwaard et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lower serum uric acid is associated with mild cognitive impairment in early Parkinson’s disease: a 4-year follow-up study

(2016) Maria Teresa Pellecchia et al.   JOURNAL OF NEURAL TRANSMISSION

Mitochondrial dysfunction in Parkinson's disease

(2016) Anindita Bose et al.   JOURNAL OF NEUROCHEMISTRY

The Mitochondrial Basis of Aging

(2016) Nuo Sun et al.   MOLECULAR CELL

Prevalence and prevention of cardiovascular disease and diabetes mellitus

(2016) Pitchai Balakumar et al.   PHARMACOLOGICAL RESEARCH

Breast cancer epidemic in the early twenty-first century: evaluation of risk factors, cumulative questionnaires and recommendations for preventive measures

(2016) Olga Golubnitschaja et al.   TUMOR BIOLOGY

Medicine in the early twenty-first century: paradigm and anticipation - EPMA position paper 2016

(2016) Olga Golubnitschaja et al.   EPMA Journal

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

(2015) Thomas M. Durcan et al.   GENES & DEVELOPMENT

NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease

(2015) V. Corsetti et al.   HUMAN MOLECULAR GENETICS

Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease

(2015) Hemi Luan et al.   PARKINSONISM & RELATED DISORDERS

Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease

(2015) Aaron R. Folsom et al.   STROKE

Decoding Warburg’s hypothesis: tumor-related mutations in the mitochondrial respiratory chain

(2015) Jose M. Garcia-Heredia et al.   Oncotarget

Mitochondrial cytopathies and cardiovascular disease

(2014) Elizabeth A Dominic et al.   HEART

Alzheimer disease and cancer risk: a meta-analysis

(2014) Hai-bin Shi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50 Observational Studies

(2014) Ferrán Catalá-López et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

(2014) Russell T. Hepple   Frontiers in Aging Neuroscience

Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease

(2013) Petar Podlesniy et al.   ANNALS OF NEUROLOGY

Prognostic Significance of Biomarkers in Predicting Outcome in Patients With Coronary Artery Disease and Left Ventricular Dysfunction

(2013) Arthur M. Feldman et al.   Circulation-Heart Failure

ADAM10 Prodomain Mutations Cause Late-Onset Alzheimer’s Disease: Not Just the Latest FAD

(2013) Robert Vassar   NEURON

CSF levels of DJ-1 and tau distinguish MSA patients from PD patients and controls

(2013) Megan K. Herbert et al.   PARKINSONISM & RELATED DISORDERS

Alzheimer's Disease

(2013) Carly Oboudiyat et al.   SEMINARS IN NEUROLOGY

Oncogenic Isocitrate Dehydrogenase Mutations: Mechanisms, Models, and Clinical Opportunities

(2013) R. A. Cairns et al.   Cancer Discovery

May Serum Levels of Advanced Oxidized Protein Products Serve as a Prognostic Marker of Disease Duration in Patients with Idiopathic Parkinson's Disease?

(2012) José-Manuel García-Moreno et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology

(2012) Robert W. Mahley et al.   NEURON

Function of DJ-1 in Mitochondria

(2012) Kazuko Takahashi-Niki et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

SDH mutations in cancer

(2011) Chiara Bardella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)

(2011) et al.   EUROPEAN HEART JOURNAL

α-Synuclein Expression Selectively Affects Tumorigenesis in Mice Modeling Parkinson's Disease

(2011) Eitan Israeli et al.   PLoS One

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

(2011) M. Sato et al.   SCIENCE

Defective DNA Replication Impairs Mitochondrial Biogenesis In Human Failing Hearts

(2010) Georgios Karamanlidis et al.   CIRCULATION RESEARCH

Mitochondrial dysfunction in neurodegenerative diseases and cancer

(2010) Michelle Barbi de Moura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The lipid peroxidation products as possible markers of Alzheimer's disease in blood

(2010) A. Skoumalová et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein

(2010) Pavel F. Pavlov et al.   FASEB JOURNAL

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea

(2010) Hélène Plun-Favreau et al.   PLoS Genetics

Predictive molecular profiling in blood of healthy vasospastic individuals: clue to targeted prevention as personalised medicine to effective costs

(2010) Kristina Yeghiazaryan et al.   EPMA Journal

Mitochondrial Death Channels

(2009) Keith Webster   AMERICAN SCIENTIST

Parkinson's Disease and Cancer

(2009) Marco D'Amelio et al.   Annals of the New York Academy of Sciences

Heterogeneity of Mitochondria and Mitochondrial Function within Cells as Another Level of Mitochondrial Complexity

(2009) Andrey Kuznetsov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Calcium Elevation in Mitochondria Is the Main Ca2+Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening

(2009) Heidi K. Baumgartner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial medicine: entering the era of treatment

(2009) S. Koene et al.   JOURNAL OF INTERNAL MEDICINE

Cardiac Troponin and Outcome in Acute Heart Failure

(2008) W. Frank Peacock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Parkin as a tumor suppressor gene for hepatocellular carcinoma

(2008) M Fujiwara et al.   ONCOGENE