PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons

Bibliometric Analysis of the Inflammasome and Pyroptosis in Brain

(2021) Yuhua Chen et al.   Frontiers in Pharmacology

Berberine Ameliorates Oxygen-glucose Deprivation/Reperfusion-induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress and Autophagy in PC12 Cells

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c-FLIP regulates pyroptosis in retinal neurons following oxygen-glucose deprivation/recovery via a GSDMD-mediated pathway

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Disulfiram inhibits inflammation and fibrosis in a rat unilateral ureteral obstruction model by inhibiting gasdermin D cleavage and pyroptosis

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Role of inflammasomes/pyroptosis and PANoptosis during fungal infection

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The Role of HSP90α in Methamphetamine/Hyperthermia-Induced Necroptosis in Rat Striatal Neurons

(2021) Lv-shuang Liao et al.   Frontiers in Pharmacology

Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease

(2021) Jing Zhang et al.   Journal of Inflammation Research

Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies

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Autophagy and post-ischemic conditioning in retinal ischemia

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RSK3 mediates necroptosis by regulating phosphorylation of RIP3 in rat retinal ganglion cells

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NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma

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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

(2020) Jun Jacob Hu et al.   NATURE IMMUNOLOGY

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

(2020) Shelbi Christgen et al.   Frontiers in Cellular and Infection Microbiology

Regulatory Role Of Chinese Herbal Medicine In Regulated Neuronal Death

(2020) Xiuyu Wu et al.   CNS & Neurological Disorders-Drug Targets

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

(2020) Parimal Samir et al.   Frontiers in Cellular and Infection Microbiology

Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy

(2020) Rong Rong et al.   Cell Death & Disease

Neuroprotective Effects of Dexmedetomidine Preconditioning on Oxygen-glucose Deprivation-reoxygenation Injury in PC12 Cells via Regulation of Ca2+-STIM1/Orai1 Signaling

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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

(2020) Rajendra Karki et al.   CELL

ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)

(2020) Balaji Banoth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PANoptosis in microbial infection

(2020) David E Place et al.   CURRENT OPINION IN MICROBIOLOGY

AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model

(2019) Xuyang Wang et al.   LIFE SCIENCES

Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion

(2019) Biji Mathew et al.   BIOMATERIALS

The levels and significance of inflammasomes in the mouse retina following optic nerve crush

(2019) Zheng Qijun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review)

(2019) Yuping Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

BRD4 suppression alleviates cerebral ischemia-induced brain injury by blocking glial activation via the inhibition of inflammatory response and pyroptosis

(2019) Yi Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

(2019) R. K. Subbarao Malireddi et al.   Frontiers in Cellular and Infection Microbiology

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

(2019) R.K. Subbarao Malireddi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells

(2019) Yani Lin et al.   TOXICOLOGY LETTERS

Fiery Cell Death: Pyroptosis in the Central Nervous System

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AIM2 accelerates the atherosclerotic plaque progressions in ApoE−/− mice

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The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury

(2018) Xintong Ge et al.   BRAIN RESEARCH

Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression

(2018) Zhen Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Remodeling of Retinal Architecture in Diabetic Retinopathy: Disruption of Ocular Physiology and Visual Functions by Inflammatory Gene Products and Pyroptosis

(2018) Rubens P. Homme et al.   Frontiers in Physiology

Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons

(2018) Shuchao Wang et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

(2018) Junying Yuan et al.   NATURE REVIEWS NEUROSCIENCE

Mechanisms governing inflammasome activation, assembly and pyroptosis induction

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Inhibition of calpain on oxygen glucose deprivation-induced RGC-5 necroptosis

(2016) Shuang Chen et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Activation of Necroptosis in Multiple Sclerosis

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Retinal ganglion cell (RGC) programmed necrosis contributes to ischemia–reperfusion-induced retinal damage

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Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

(2014) Nicolás Cuenca et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

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Differential neuronal expression of receptor interacting protein 3 in rat retina: involvement in ischemic stress response

(2013) Ju-Fang Huang et al.   BMC NEUROSCIENCE

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

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Molecular mechanisms of necroptosis: an ordered cellular explosion

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Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells

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Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology