TRIM31 inhibits NLRP3 inflammasome and pyroptosis of retinal pigment epithelial cells through ubiquitination of NLRP3

TRIM31 promotes glioma proliferation and invasion through activating NF-κB pathway

(2019) Li Zhou et al.   OncoTargets and Therapy

Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9

(2017) Jillian P. Rhoads et al.   JOURNAL OF IMMUNOLOGY

TRIM31 is upregulated in hepatocellular carcinoma and promotes disease progression by inducing ubiquitination of TSC1–TSC2 complex

(2017) P Guo et al.   ONCOGENE

Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration

(2017) Frank G. Holz et al.   OPHTHALMOLOGY

p38δ MAPKHighlights

(2016) Kristiina Rajamäki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

(2016) Hui Song et al.   Nature Communications

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

(2016) Lei Wang et al.   Oncotarget

The genetics of age-related macular degeneration (AMD) – Novel targets for designing treatment options?

(2015) Felix Grassmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

(2015) Jiangyuan Gao et al.   MEDIATORS OF INFLAMMATION

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

TRIM31 is downregulated in non-small cell lung cancer and serves as a potential tumor suppressor

(2014) Hui Li et al.   TUMOR BIOLOGY

Outer Retinal Corrugations in Age-Related Macular Degeneration

(2014) Sotaro Ooto et al.   JAMA Ophthalmology

Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis

(2013) Matthew Brentnall et al.   BMC CELL BIOLOGY

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

(2013) Youssef Aachoui et al.   CURRENT OPINION IN MICROBIOLOGY

The NLRP3 Inflammasome in Alzheimer’s Disease

(2013) Meng-Shan Tan et al.   MOLECULAR NEUROBIOLOGY

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

(2012) Yugang Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

The cellular level of TRIM31, an RBCC protein overexpressed in gastric cancer, is regulated by multiple mechanisms including the ubiquitin–proteasome system

(2011) Takeyuki Sugiura   CELL BIOLOGY INTERNATIONAL

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

Biological effects of native and oxidized low-density lipoproteins in cultured human retinal pigment epithelial cells

(2008) Alice L. Yu et al.   EXPERIMENTAL EYE RESEARCH