Dual-Parameter Recognition-Directed Design of the Activatable Fluorescence Probe for Precise Imaging of Cellular Senescence

Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for Broad‐Spectrum Senotherapy

(2022) Yinghao Xia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Activatable NIR Probe for the Detection and Elimination of Senescent Cells

(2022) Liu Yang et al.   ANALYTICAL CHEMISTRY

Lipofuscin labeling through biorthogonal strain‐promoted azide‐alkyne cycloaddition for the detection of senescent cells

(2022) Beatriz Lozano‐Torres et al.   FEBS Journal

A Self-Immolative Fluorescent Probe for Selective Detection of SARS-CoV-2 Main Protease

(2022) Ming Xu et al.   ANALYTICAL CHEMISTRY

A Tandemly Activated Fluorescence Probe for Detecting Senescent Cells with Improved Selectivity by Targeting a Biomarker Combination

(2022) Lei Zhou et al.   ACS Sensors

Targeted Imaging in Atherosclerosis

(2022) Jingjing Li et al.   ANALYTICAL CHEMISTRY

Monoamine oxidases in age-associated diseases: New perspectives for old enzymes

(2021) Yohan Santin et al.   AGEING RESEARCH REVIEWS

Chromo-fluorogenic probes for β-galactosidase detection

(2021) Beatriz Lozano-Torres et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Water-Soluble Near-Infrared Fluorescent Probes for Specific Detection of Monoamine Oxidase A in Living Biosystems

(2021) Jizhen Shang et al.   ANALYTICAL CHEMISTRY

A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the In Vivo Tracking of Cellular Senescence

(2021) Beatriz Lozano-Torres et al.   ANALYTICAL CHEMISTRY

Two‐Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence

(2021) Yuan Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

AND-Logic Strategy for Accurate Analysis of Alzheimer’s Disease via Fluorescent Probe Lighted Up by Two Specific Biomarkers

(2021) Peng Zhang et al.   ANALYTICAL CHEMISTRY

The Emergence of Senescent Surface Biomarkers as Senotherapeutic Targets

(2021) Martina Rossi et al.   Cells

Aging Diagnostic Probe for Research on Aging and Evaluation of Anti-aging Drug Efficacy

(2021) Zihong Li et al.   ANALYTICAL CHEMISTRY

Activatable fluorescent probes for in situ imaging of enzymes

(2021) Xiaofeng Wu et al.   CHEMICAL SOCIETY REVIEWS

Noninvasive NIR Imaging of Senescence via In Situ Labeling

(2021) Jun Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorescence-Based Detection of Ferrous Iron in Senescent Cells

(2021) Kyle J. Parella et al.   REJUVENATION RESEARCH

Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity

(2020) Estela González‐Gualda et al.   AGING CELL

Real time in vivo detection of cellular senescence through the controlled release of the NIR fluorescent dye Nile Blue

(2020) Beatriz Lozano-Torres et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional heterogeneity in senescence

(2020) Kristina Kirschner et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

In vivo imaging of senescent vascular cells in atherosclerotic mice using a β-galactosidase-activatable nanoprobe

(2020) Ji-An Chen et al.   ANALYTICAL CHEMISTRY

Senescence and Cancer: A Review of Clinical Implications of Senescence and Senotherapies

(2020) Lynda Wyld et al.   Cancers

A guide to assessing cellular senescence in vitro and in vivo

(2020) Estela González‐Gualda et al.   FEBS Journal

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Measuring biological aging in humans: A quest

(2019) Luigi Ferrucci et al.   AGING CELL

Senescence-associated sialidase revealed by an activatable fluorescence-on labeling probe

(2018) Rui Zhu et al.   CHEMICAL COMMUNICATIONS

An OFF–ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo

(2017) Beatriz Lozano-Torres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

(2017) Roksana M Pirzgalska et al.   NATURE MEDICINE

Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing

(2017) Damien Maggiorani et al.   Oxidative Medicine and Cellular Longevity

Sensitive and Selective Ratiometric Fluorescence Probes for Detection of Intracellular Endogenous Monoamine Oxidase A

(2015) Xiaofeng Wu et al.   ANALYTICAL CHEMISTRY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE