A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the In Vivo Tracking of Cellular Senescence

Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity

(2020) Estela González‐Gualda et al.   AGING CELL

Real time in vivo detection of cellular senescence through the controlled release of the NIR fluorescent dye Nile Blue

(2020) Beatriz Lozano-Torres et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic

(2020) Irene Galiana et al.   JOURNAL OF CONTROLLED RELEASE

The chemistry of senescence

(2019) Beatriz Lozano-Torres et al.   Nature Reviews Chemistry

Targeting senescent cells in translational medicine

(2019) Marta Paez‐Ribes et al.   EMBO Molecular Medicine

Is DNA damage indispensable for stress-induced senescence?

(2018) Anna Bielak-Zmijewska et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

A Versatile New Paradigm for the Design of Optical Nanosensors Based on Enzyme-Mediated Detachment of Labeled Reporters: The Example of Urea Detection

(2018) Antoni Llopis-Lorente et al.   CHEMISTRY-A EUROPEAN JOURNAL

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

(2017) Birgit Ritschka et al.   GENES & DEVELOPMENT

Senescence and aging: Causes, consequences, and therapeutic avenues

(2017) Domhnall McHugh et al.   JOURNAL OF CELL BIOLOGY

An OFF–ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo

(2017) Beatriz Lozano-Torres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex

(2017) Cristina de la Torre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibitors of cyclin-dependent kinases as cancer therapeutics

(2017) Steven R. Whittaker et al.   PHARMACOLOGY & THERAPEUTICS

A versatile two-photon fluorescent probe for ratiometric imaging E. coli β-galactosidase in live cells and in vivo

(2016) Xue-Xiang Zhang et al.   CHEMICAL COMMUNICATIONS

HMGB2 holds the key to the senescence-associated secretory phenotype

(2016) Ana Guerrero et al.   JOURNAL OF CELL BIOLOGY

Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

(2016) Kaizhi Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A

(2015) Zi-Ru Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A fluorescent light-up probe based on AIE and ESIPT processes for β-galactosidase activity detection and visualization in living cells

(2015) Lu Peng et al.   Journal of Materials Chemistry B

Ratiometric Two-Photon Fluorescent Probe for Quantitative Detection of β-Galactosidase Activity in Senescent Cells

(2014) Hyo Won Lee et al.   ANALYTICAL CHEMISTRY

Senescence and apoptosis: dueling or complementary cell fates?

(2014) B. G. Childs et al.   EMBO REPORTS

Molecular Engineering of a TBET-Based Two-Photon Fluorescent Probe for Ratiometric Imaging of Living Cells and Tissues

(2014) Liyi Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Chromo-Fluorogenic Synthetic “Canary” for CO Detection Based on a Pyrenylvinyl Ruthenium(II) Complex

(2014) María E. Moragues et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A fluorogenic probe for β-galactosidase activity imaging in living cells

(2013) Junyan Han et al.   Molecular BioSystems

Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold

(2012) Daihi Oushiki et al.   ANALYTICAL CHEMISTRY

Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization

(2012) Masayo Sakabe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible well-defined chromophore–polymer conjugates for photodynamic therapy and two-photon imaging

(2012) Cristina Cepraga et al.   Polymer Chemistry

Development of a fluorescein analogue, TokyoMagenta, as a novel scaffold for fluorescence probes in red region

(2011) Takahiro Egawa et al.   CHEMICAL COMMUNICATIONS

β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold

(2011) Mako Kamiya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE