Noninvasive NIR Imaging of Senescence via In Situ Labeling

Two‐Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence

(2021) Yuan Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Real-time imaging of senescence in tumors with DNA damage

(2019) Ying Wang et al.   Scientific Reports

Genetically Encoding Photocaged Quinone Methide to Multitarget Protein Residues Covalently in Vivo

(2019) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The chemistry of senescence

(2019) Beatriz Lozano-Torres et al.   Nature Reviews Chemistry

Activatable Photosensitizer for Targeted Ablation of lacZ-Positive Cells with Single-Cell Resolution

(2019) Mayumi Chiba et al.   ACS Central Science

Photocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes

(2019) Jun Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Development of highly sensitive fluorescent probes for the detection of β-galactosidase activity – application to the real-time monitoring of senescence in live cells

(2018) Mauro Safir Filho et al.   ANALYST

Ratiometric fluorescent probes with a self-immolative spacer for real-time detection of β -galactosidase and imaging in living cells

(2018) Xiangzhu Chen et al.   ANALYTICA CHIMICA ACTA

Proximity Ligation-Based Fluorogenic Imaging Agents for Neuraminidases

(2018) Zhizeng Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Red-shifted fluorogenic substrate for detecting lacZ-positive cells in living tissue with single-cell resolution

(2018) Hiroki Ito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2

(2018) Jing Ning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An OFF–ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo

(2017) Beatriz Lozano-Torres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tissue-Specific Near-Infrared Fluorescence Imaging

(2016) Eric A. Owens et al.   ACCOUNTS OF CHEMICAL RESEARCH

Detection of LacZ -Positive Cells in Living Tissue with Single-Cell Resolution

(2016) Tomohiro Doura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Near-Infrared Fluorescent Probe with New Recognition Moiety for Specific Detection of Tyrosinase Activity: Design, Synthesis, and Application in Living Cells and Zebrafish

(2016) Xiaofeng Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Self-Immobilizing and Fluorogenic Probe for β-Lactamase Detection

(2016) Wuyu Mao et al.   Chemistry-An Asian Journal

Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

(2016) Kaizhi Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

in vivo imaging and detection of nitroreductase in zebrafish by a new near-infrared fluorescence off–on probe

(2015) Zhao Li et al.   BIOSENSORS & BIOELECTRONICS

Recent advances in the development of synthetic chemical probes for glycosidase enzymes

(2015) Helen M. Burke et al.   CHEMICAL COMMUNICATIONS

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

Sensitive and Selective Near-Infrared Fluorescent Off–On Probe and Its Application to Imaging Different Levels of β-Lactamase in Staphylococcus aureus

(2014) Lihong Li et al.   ANALYTICAL CHEMISTRY

A Fast and Selective Near-Infrared Fluorescent Sensor for Multicolor Imaging of Biological Nitroxyl (HNO)

(2014) Alexandra T. Wrobel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recent progress in the development of near-infrared fluorescent probes for bioimaging applications

(2013) Zhiqian Guo et al.   CHEMICAL SOCIETY REVIEWS

Long-Term Fluorescent Cellular Tracing by the Aggregates of AIE Bioconjugates

(2013) Zhengke Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and use of QCy7-derived modular probes for the detection and imaging of biologically relevant analytes

(2013) Orit Redy-Keisar et al.   Nature Protocols

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

(2012) Lin Yuan et al.   CHEMICAL SOCIETY REVIEWS

A Unique Approach to Development of Near-Infrared Fluorescent Sensors for in Vivo Imaging

(2012) Lin Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization

(2012) Masayo Sakabe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a fluorescein analogue, TokyoMagenta, as a novel scaffold for fluorescence probes in red region

(2011) Takahiro Egawa et al.   CHEMICAL COMMUNICATIONS

β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold

(2011) Mako Kamiya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Paradigm for a Turn-ON Near-Infrared Cyanine-Based Probe: Noninvasive Intravital Optical Imaging of Hydrogen Peroxide

(2011) Naama Karton-Lifshin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Immobilizing Fluorogenic Imaging Agents of Enzyme Activity

(2010) David H. Kwan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols