The PCK2-glycolysis axis assists three-dimensional-stiffness maintaining stem cell osteogenesis

PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease

(2021) Maria E. Moreno-Fernandez et al.   Cell Metabolism

Cytoskeletal prestress: The cellular hallmark in mechanobiology and mechanomedicine

(2021) Farhan Chowdhury et al.   Cytoskeleton

Adhesion-mediated mechanosignaling forces mitohormesis

(2021) Kevin M. Tharp et al.   Cell Metabolism

Mechanical regulation of glycolysis via cytoskeleton architecture

(2020) Jin Suk Park et al.   NATURE

TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding

(2020) Xueyou Zhang et al.   Aging-US

Novel approach for pathogenesis of osteoporosis in ovariectomized rats as a model of postmenopausal osteoporosis

(2020) NermineK. Saleh et al.   EXPERIMENTAL GERONTOLOGY

The molecular mechanism of mechanotransduction in vascular homeostasis and disease

(2020) Yoshito Yamashiro et al.   CLINICAL SCIENCE

Effects of biophysical cues of 3D hydrogels on mesenchymal stem cells differentiation

(2020) Yutong Guo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects

(2019) Chi Yang et al.   Stem Cell Research & Therapy

Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments

(2019) Hong-pyo Lee et al.   Nature Communications

Intracellular citrate accumulation by oxidized ATM-mediated metabolism reprogramming via PFKP and CS enhances hypoxic breast cancer cell invasion and metastasis

(2019) Meixi Peng et al.   Cell Death & Disease

Increased glycolysis mediates Wnt7b-induced bone formation

(2019) Hong Chen et al.   FASEB JOURNAL

Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

(2019) Yilin Yu et al.   Cell Metabolism

Chirality Controls Mesenchymal Stem Cell Lineage Diversification through Mechanoresponses

(2019) Yan Wei et al.   ADVANCED MATERIALS

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: Challenges, opportunities, and future perspectives

(2019) Shobha Regmi et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Extracellular matrix type modulates mechanotransduction of stem cells

(2019) Alice E. Stanton et al.   Acta Biomaterialia

Bone-Forming and Antiresorptive Effects of Romosozumab in Postmenopausal Women With Osteoporosis: Bone Histomorphometry and Microcomputed Tomography Analysis After 2 and 12 Months of Treatment

(2019) Pascale Chavassieux et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates osteogenic differentiation by modulating AMPK/ULK1-dependent autophagy

(2019) Zheng Li et al.   STEM CELLS

Asymmetrical methyltransferase PRMT3 regulates human mesenchymal stem cell osteogenesis via miR-3648

(2019) Zhang Min et al.   Cell Death & Disease

Lineage Commitment, Signaling Pathways, and the Cytoskeleton Systems in Mesenchymal Stem Cells

(2019) Aleena A. Saidova et al.   TISSUE ENGINEERING PART B-REVIEWS

RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects

(2018) Minh K. Nguyen et al.   Acta Biomaterialia

Lancet Commission: Stem cells and regenerative medicine

(2018) Giulio Cossu et al.   LANCET

Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics

(2018) Lucas R. Smith et al.   PHYSIOLOGY

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells

(2018) Katharina Leithner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials

(2018) Marsha C. Lampi et al.   Science Translational Medicine

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

(2018) Meiyu Sun et al.   Stem Cell Research & Therapy

RNA-seq reveals diverse effects of substrate stiffness on mesenchymal stem cells

(2018) Max Darnell et al.   BIOMATERIALS

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

(2018) William J. Sullivan et al.   CELL

Assessing bone quality through mechanical properties in postmenopausal trabecular bone

(2018) Manuel Toledano et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Inhibition of glycolysis alleviates lipopolysaccharide-induced acute lung injury in a mouse model

(2018) Wen-Jing Zhong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer

(2018) Mengyu Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

(2018) Lei Chang et al.   NATURE

The Role of the Lysyl Oxidases in Tissue Repair and Remodeling: A Concise Review

(2017) Linyi Cai et al.   Tissue Engineering and Regenerative Medicine

The Role of the Lysyl Oxidases in Tissue Repair and Remodeling: A Concise Review

(2017) Linyi Cai et al.   Tissue Engineering and Regenerative Medicine

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton

(2016) Hai Hu et al.   CELL

Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer’s Disease: Baseline Data from a DIAN Cohort Subset

(2015) Pratishtha Chatterjee et al.   Current Alzheimer Research

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Inhibition of pentose phosphate pathway suppresses acute myelogenous leukemia

(2015) Yan Chen et al.   TUMOR BIOLOGY

Tissue Stiffness Dictates Development, Homeostasis, and Disease Progression

(2015) Andrew M Handorf et al.   Organogenesis

Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability

(2014) Andrés Méndez-Lucas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

PCK2 activation mediates an adaptive response to glucose depletion in lung cancer

(2014) K Leithner et al.   ONCOGENE

Aerobic Glycolysis in Osteoblasts

(2014) Emel Esen et al.   Current Osteoporosis Reports

Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels

(2011) Wenqian Xiao et al.   Acta Biomaterialia

Mechanotransduction at cadherin-mediated adhesions

(2011) Deborah E Leckband et al.   CURRENT OPINION IN CELL BIOLOGY

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Designing materials to direct stem-cell fate

(2009) Matthias P. Lutolf et al.   NATURE

Human iliac crest cancellous bone elastic modulus and hardness differ with bone formation rate per bone surface but not by existence of prevalent vertebral fracture

(2007) Xiang Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS