The Role of the Lysyl Oxidases in Tissue Repair and Remodeling: A Concise Review

Inhibition of development of experimental abdominal aortic aneurysm by c-jun N-terminal protein kinase inhibitor combined with lysyl oxidase gene modified smooth muscle progenitor cells

(2015) Feng Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications

(2015) Łukasz A. Poniatowski et al.   MEDIATORS OF INFLAMMATION

Combined use of chondroitinase-ABC, TGF-β1, and collagen crosslinking agent lysyl oxidase to engineer functional neotissues for fibrocartilage repair

(2014) Eleftherios A. Makris et al.   BIOMATERIALS

Differential expressions of the lysyl oxidase family and matrix metalloproteinases-1, 2, 3 in posterior cruciate ligament fibroblasts after being co-cultured with synovial cells

(2014) Chunli Wang et al.   INTERNATIONAL ORTHOPAEDICS

Biomechanics and mechanobiology in functional tissue engineering

(2014) Farshid Guilak et al.   JOURNAL OF BIOMECHANICS

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(2014) Michael Brines   MOLECULAR MEDICINE

Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase-induced collagen cross-linking

(2014) Eleftherios A. Makris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connective tissue and inflammation

(2014) Lajos Jakab   ORVOSI HETILAP

Estrogen Alters Remodeling of the Vaginal Wall after Surgical Injury in Guinea Pigs1

(2013) Sunil Balgobin et al.   BIOLOGY OF REPRODUCTION

Engineering functional anisotropy in fibrocartilage neotissues

(2013) Regina F. MacBarb et al.   BIOMATERIALS

Prostaglandin E 2 Inhibits Elastogenesis in the Ductus Arteriosus via EP4 Signaling

(2013) Utako Yokoyama et al.   CIRCULATION

TNF-α induced down-regulation of lysyl oxidase family in anterior cruciate ligament and medial collateral ligament fibroblasts

(2013) Jing Xie et al.   KNEE

Influence of TNF-α and biomechanical stress on matrix metalloproteinases and lysyl oxidases expressions in human knee synovial fibroblasts

(2013) Yanjun Zhang et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Hypoxia-induced collagen crosslinking as a mechanism for enhancing mechanical properties of engineered articular cartilage

(2013) E.A. Makris et al.   OSTEOARTHRITIS AND CARTILAGE

Transforming Growth Factor β1 Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts

(2013) Xiaodong Pan et al.   PLoS One

Induced Collagen Cross-Links Enhance Cartilage Integration

(2013) Aristos A. Athens et al.   PLoS One

Characterization of mechanical and biochemical properties of developing embryonic tendon

(2013) J. E. Marturano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of fibronectin in normal wound healing

(2013) Ellie A Lenselink   International Wound Journal

Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue DiseasesPossibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure

(2012) Morten A. Karsdal et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells

(2012) Susanna Teppo et al.   EXPERIMENTAL CELL RESEARCH

Differential expressions of lysyl oxidase family in ACL and MCL fibroblasts after mechanical injury

(2012) Jing Xie et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Micronutrient modulation of NF-κB in oral keratinocytes exposed to periodontal bacteria

(2012) Michael R Milward et al.   Innate Immunity

Interleukin-1 beta influences on lysyl oxidases and matrix metalloproteinases profile of injured anterior cruciate ligament and medial collateral ligament fibroblasts

(2012) Jing Xie et al.   INTERNATIONAL ORTHOPAEDICS

Regional mechanics determine collagen fiber structure in healing myocardial infarcts

(2012) Gregory M. Fomovsky et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential regulation of collagen, lysyl oxidase and MMP-2 in human periodontal ligament cells by low- and high-level mechanical stretching

(2012) Y-J. Chen et al.   JOURNAL OF PERIODONTAL RESEARCH

Mechanical regulation of fibroblast migration and collagen remodelling in healing myocardial infarcts

(2012) Andrew D. Rouillard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Unlike Bone, Cartilage Regeneration Remains Elusive

(2012) D. J. Huey et al.   SCIENCE

Mesenchymal stem cell therapy for attenuation of scar formation during wound healing

(2012) Wesley M Jackson et al.   Stem Cell Research & Therapy

Copper Dependence of Angioproliferation in Pulmonary Arterial Hypertension in Rats and Humans

(2011) Harm J. Bogaard et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

(2011) M. Bignon et al.   BLOOD

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling

(2011) Tetyana G. Voloshenyuk et al.   CYTOKINE

Up-regulation expressions of lysyl oxidase family in Anterior Cruciate Ligament and Medial Collateral Ligament fibroblasts induced by Transforming Growth Factor-Beta 1

(2011) Jing Xie et al.   INTERNATIONAL ORTHOPAEDICS

IL1α and IL4 signalling in human ovarian surface epithelial cells

(2011) Georgia Papacleovoulou et al.   JOURNAL OF ENDOCRINOLOGY

Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation

(2011) Oliver Adam et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Recovery of the Injured External Anal Sphincter After Injection of Local or Intravenous Mesenchymal Stem Cells

(2011) Sujatha D. Pathi et al.   OBSTETRICS AND GYNECOLOGY

Tensile Properties, Collagen Content, and Crosslinks in Connective Tissues of the Immature Knee Joint

(2011) Sriram V. Eleswarapu et al.   PLoS One

Evaluation of Treatment Effectiveness for the Herniated Cervical Disc

(2011) Lukas Gebremariam et al.   SPINE

Fibroblast Function and Wound Breaking Strength Is Impaired by Acute Ethanol Intoxication

(2010) Matthew J. Ranzer et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

High Glucose Increases Lysyl Oxidase Expression and Activity in Retinal Endothelial Cells: Mechanism for Compromised Extracellular Matrix Barrier Function

(2010) A. Chronopoulos et al.   DIABETES

Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-β1 in cultured cardiac fibroblasts

(2010) Kou-Gi Shyu et al.   EUROPEAN JOURNAL OF HEART FAILURE

Strategies for prevention of scars: what can we learn from fetal skin?

(2010) Mohammad Reza Namazi et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Controlling matrix formation and cross-linking by hypoxia in cardiovascular tissue engineering

(2010) Marijke A. A. van Vlimmeren et al.   JOURNAL OF APPLIED PHYSIOLOGY

Homocysteine Suppresses the Expression of the Collagen Cross-linker Lysyl Oxidase Involving IL-6,Fli1, and Epigenetic DNA Methylation

(2010) Roman Thaler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysyl Oxidase-like-2 (LOXL2) Is a Major Isoform in Chondrocytes and Is Critically Required for Differentiation

(2010) Mussadiq Iftikhar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin

(2010) Young-Mi Kim et al.   MOLECULAR BIOLOGY REPORTS

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Lysyl oxidase: a potential target for cancer therapy

(2010) Siddikuzzaman et al.   INFLAMMOPHARMACOLOGY

ICAM-1 Is Necessary for Epithelial Recruitment of γδ T Cells and Efficient Corneal Wound Healing

(2009) Sarah E. Byeseda et al.   AMERICAN JOURNAL OF PATHOLOGY

Accelerated Healing of the Rat Achilles Tendon in Response to Autologous Conditioned Serum

(2009) Martin Majewski et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

The roles of TGF-β1 gene transfer on collagen formation during Achilles tendon healing

(2009) Yu Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhanced proliferation capacity of porcine tenocytes in low O2 tension culture

(2009) Yanjie Zhang et al.   BIOTECHNOLOGY LETTERS

Hypoxia Induces Near-Native Mechanical Properties in Engineered Heart Valve Tissue

(2009) Angelique Balguid et al.   CIRCULATION

Rat Achilles tendon healing: mechanical loading and gene expression

(2009) Pernilla Eliasson et al.   JOURNAL OF APPLIED PHYSIOLOGY

The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction

(2009) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lysyl oxidase enhances elastin synthesis and matrix formation by vascular smooth muscle cells

(2009) Chandrasekhar R. Kothapalli et al.   Journal of Tissue Engineering and Regenerative Medicine

Healing of meniscal tissue by cellular fibrin glue: an in vivo study

(2009) C. Scotti et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus

(2009) M. Saito et al.   OSTEOPOROSIS INTERNATIONAL

Transcriptional Analysis of Fracture Healing and the Induction of Embryonic Stem Cell–Related Genes

(2009) Manish Bais et al.   PLoS One

Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after a mechanical injury: Involvement of the p65 subunit of NF-κB

(2009) Zhenyu Tang et al.   WOUND REPAIR AND REGENERATION

Interactions between extracellular matrix and growth factors in wound healing

(2009) Gregory S. Schultz et al.   WOUND REPAIR AND REGENERATION

Copper nanoparticle cues for biomimetic cellular assembly of crosslinked elastin fibers

(2008) Chandrasekhar R. Kothapalli et al.   Acta Biomaterialia

Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis

(2008) Takashi Urashima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development

(2008) Chisa Shukunami et al.   CELL AND TISSUE RESEARCH

A coordinated approach to cutaneous wound healing: vibrational microscopy and molecular biology

(2008) K. L. Andrew Chan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Contributions of different intraarticular tissues to the acute phase elevation of synovial fluid MMP-2 following rat ACL rupture

(2008) Zhenyu Tang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Transforming Growth Factor Beta 1 and Hyaluronan Oligomers Synergistically Enhance Elastin Matrix Regeneration by Vascular Smooth Muscle Cells

(2008) Chandrasekhar R. Kothapalli et al.   TISSUE ENGINEERING PART A

Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells

(2007) Sonia Aydin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines

(2007) Javier et al.   Frontiers in Bioscience-Landmark

Cartilage growth and remodeling: modulation of balance between proteoglycan and collagen network in vitro with β-aminopropionitrile

(2007) A. Asanbaeva et al.   OSTEOARTHRITIS AND CARTILAGE

Contribution of collagen network features to functional properties of engineered cartilage

(2007) Y.M. Bastiaansen-Jenniskens et al.   OSTEOARTHRITIS AND CARTILAGE