Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice
Authors
Keywords
-
Journal
Antioxidants
Volume 12, Issue 1, Pages 92
Publisher
MDPI AG
Online
2023-01-02
DOI
10.3390/antiox12010092
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Icariin attenuates cyclophosphamide-induced cystitis via down-regulation of NF-кB and up-regulation of Nrf-2/HO-1 signaling pathways in mice model
- (2022) Safa Amanat et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Pathophysiology, assessment, and treatment of overactive bladder symptoms in patients with interstitial cystitis/bladder pain syndrome
- (2022) Amy D. Dobberfuhl NEUROUROLOGY AND URODYNAMICS
- Setanaxib (GKT137831) Ameliorates Doxorubicin-Induced Cardiotoxicity by Inhibiting the NOX1/NOX4/Reactive Oxygen Species/MAPK Pathway
- (2022) Hui Zheng et al. Frontiers in Pharmacology
- Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure
- (2022) Akila L. Oliveira et al. Frontiers in Physiology
- Architecture of the NADPH oxidase family of enzymes
- (2022) Blessing C. Ogboo et al. Redox Biology
- Urine Oxidative Stress Biomarkers as Novel Biomarkers in Interstitial Cystitis/Bladder Pain Syndrome
- (2022) Yuan-Hong Jiang et al. Biomedicines
- Nrf2 Pathway Ameliorates Bladder Dysfunction in Cyclophosphamide-Induced Cystitis via Suppression of Oxidative Stress
- (2021) Bin Ni et al. Oxidative Medicine and Cellular Longevity
- A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia–reperfusion in the mouse heart
- (2021) Ferenc L. M. Szekeres et al. Scientific Reports
- NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology
- (2021) Annelise Vermot et al. Antioxidants
- Hidrox ® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain
- (2021) Ramona D’Amico et al. Antioxidants
- An Effective NADPH Oxidase 2 Inhibitor Provides Neuroprotection and Improves Functional Outcomes in Animal Model of Traumatic Brain Injury
- (2020) Mengwei Wang et al. NEUROCHEMICAL RESEARCH
- On the Clinical Pharmacology of Reactive Oxygen Species
- (2020) Ana I. Casas et al. PHARMACOLOGICAL REVIEWS
- Uroprotective effect of ambroxol in cyclophosphamide-induced cystitis in mice
- (2019) Elif Nur Barut et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts
- (2019) Lidija Milkovic et al. Cells
- Cannabinoid receptor 2 activation decreases severity of cyclophosphamide‐induced cystitis via regulating autophagy
- (2019) Qinggang Liu et al. NEUROUROLOGY AND URODYNAMICS
- The NADPH Oxidase Family and Its Inhibitors
- (2019) Mathieu Chocry et al. ANTIOXIDANTS & REDOX SIGNALING
- Obesity-induced mouse benign prostatic hyperplasia (BPH) is improved by treatment with resveratrol: implication of oxidative stress, insulin sensitivity and neuronal growth factor
- (2018) Fabiano B. Calmasini et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury
- (2018) Bo Young Jeong et al. PLoS One
- Influence of the periprostatic adipose tissue in obesity-associated mouse urethral dysfunction and oxidative stress: Effect of resveratrol treatment
- (2018) Eduardo C. Alexandre et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction
- (2018) Si-yu Zeng et al. BIOMEDICINE & PHARMACOTHERAPY
- The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice
- (2018) Yu Cui et al. PLoS One
- Methods Used to Evaluate Pain Behaviors in Rodents
- (2017) Jennifer R. Deuis et al. Frontiers in Molecular Neuroscience
- Therapeutic potential of NADPH oxidase 1/4 inhibitors
- (2016) G Teixeira et al. BRITISH JOURNAL OF PHARMACOLOGY
- A standard for terminology in chronic pelvic pain syndromes: A report from the chronic pelvic pain working group of the international continence society
- (2016) Regula Doggweiler et al. NEUROUROLOGY AND URODYNAMICS
- Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor
- (2015) Kazufumi Hirano et al. ANTIOXIDANTS & REDOX SIGNALING
- Evaluation of oxidative stress status and antioxidant capacity in patients with painful bladder syndrome/interstitial cystitis: preliminary results of a randomised study
- (2015) Kemal Ener et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Enhanced endothelium-dependent relaxation of rat pulmonary artery following β-adrenergic overstimulation: Involvement of the NO/cGMP/VASP pathway
- (2015) Ana P. Davel et al. LIFE SCIENCES
- The Effects of Tempol on Cyclophosphamide-Induced Oxidative Stress in Rat Micturition Reflexes
- (2015) Eric J. Gonzalez et al. TheScientificWorldJOURNAL
- The Effects of Tempol on Cyclophosphamide-Induced Oxidative Stress in Rat Micturition Reflexes
- (2015) Eric J. Gonzalez et al. Scientific World Journal
- Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna
- (2014) Ibrahim Keles et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite
- (2013) S. Schildknecht et al. CURRENT MEDICINAL CHEMISTRY
- Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder
- (2013) Céline Augé et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
- (2012) K. Shimada et al. CLINICAL CANCER RESEARCH
- Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes
- (2012) Mona Sedeek et al. CLINICAL SCIENCE
- TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma
- (2012) Huei-Sheng Huang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome
- (2012) Jane-Dar Lee et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study
- (2012) Susan Keay et al. BMC Urology
- ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder
- (2011) Keiji Shimada et al. BMC Urology
- NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain
- (2010) D. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Formation and maintenance of blood–urine barrier in urothelium
- (2010) Mateja Erdani Kreft et al. PROTOPLASMA
- A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression
- (2009) K. Shimada et al. CANCER RESEARCH
- Cyclophosphamide and cancer: golden anniversary
- (2009) Ashkan Emadi et al. Nature Reviews Clinical Oncology
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started