Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis

Free Radical Chain Reactions and Polyunsaturated Fatty Acids in Brain Lipids

(2022) Sharon C. W. Ng et al.   ACS Omega

The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration

(2021) Shofiul Azam et al.   Frontiers in Cell and Developmental Biology

Deletion of Neuronal CuZnSOD Accelerates Age-Associated Muscle Mitochondria and Calcium Handling Dysfunction That Is Independent of Denervation and Precedes Sarcopenia

(2021) Yu Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Assessing Lumbar Plexus and Sciatic Nerve Damage in Relapsing-Remitting Multiple Sclerosis Using Magnetisation Transfer Ratio

(2021) Ratthaporn Boonsuth et al.   Frontiers in Neurology

The assessment of mouse spontaneous locomotor activity using motion picture

(2020) Koji Kobayashi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Molecular changes associated with spinal cord aging

(2020) Katarzyna M. Piekarz et al.   GeroScience

NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients

(2020) Sunny Malhotra et al.   BRAIN

SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration

(2020) Kwang Woo Ko et al.   JOURNAL OF CELL BIOLOGY

Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice

(2020) Shylesh Bhaskaran et al.   AGING CELL

Detection of Cerebrovascular Loss in the Normal Aging C57BL/6 Mouse Brain Using in vivo Contrast-Enhanced Magnetic Resonance Angiography

(2020) Lindsay K. Hill et al.   Frontiers in Aging Neuroscience

Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice

(2020) Rizwan Qaisar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

(2019) Bumsoo Ahn et al.   Journal of Cachexia Sarcopenia and Muscle

Axonal degeneration is mediated by necroptosis activation

(2019) Macarena S. Arrázola et al.   JOURNAL OF NEUROSCIENCE

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β

(2019) Juliana Komuczki et al.   IMMUNITY

Progressive multiple sclerosis: from pathophysiology to therapeutic strategies

(2019) Simon Faissner et al.   NATURE REVIEWS DRUG DISCOVERY

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

(2019) Maritza Oñate et al.   CELL DEATH AND DIFFERENTIATION

High Speed Ventral Plane Videography as a Convenient Tool to Quantify Motor Deficits during Pre-Clinical Experimental Autoimmune Encephalomyelitis

(2019) Zhan et al.   Cells

Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis

(2018) Xiaoming Jia et al.   ANNALS OF NEUROLOGY

Loss of mitochondrial protease ClpP protects mice from diet‐induced obesity and insulin resistance

(2018) Shylesh Bhaskaran et al.   EMBO REPORTS

Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis

(2018) Graham Campbell et al.   FEBS LETTERS

Necroptosis: a regulated inflammatory mode of cell death

(2018) Yogesh K. Dhuriya et al.   Journal of Neuroinflammation

Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness

(2018) Rizwan Qaisar et al.   Redox Biology

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

(2018) Junying Yuan et al.   NATURE REVIEWS NEUROSCIENCE

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress Induced by Lipid Peroxidation Is Related with Inflammation of Demyelination and Neurodegeneration in Multiple Sclerosis

(2017) Pin Wang et al.   EUROPEAN NEUROLOGY

Necroptosis and Inflammation

(2016) Kim Newton et al.   Annual Review of Biochemistry

Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

(2016) Yong Hwan Han et al.   DIABETES

Oxidative stress in multiple sclerosis: Central and peripheral mode of action

(2016) Kim Ohl et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

(2016) Mona Sadeghian et al.   Scientific Reports

Hereditary spastic paraplegia-linked REEP1 modulates endoplasmic reticulum/mitochondria contacts

(2015) Youngshin Lim et al.   ANNALS OF NEUROLOGY

Oxidative stress and Parkinson’s disease

(2015) Javier Blesa et al.   Frontiers in Neuroanatomy

Activation of Necroptosis in Multiple Sclerosis

(2015) Dimitry Ofengeim et al.   Cell Reports

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

(2015) Kavithalakshmi Sataranatarajan et al.   Redox Biology

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice

(2014) Michael E. Walsh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Curcumin Inhibits Mitochondrial Injury and Apoptosis from the Early Stage in EAE Mice

(2014) Jinzhou Feng et al.   Oxidative Medicine and Cellular Longevity

Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis

(2013) Mascha S. Recks et al.   CLINICAL IMMUNOLOGY

Mitochondrial changes within axons in multiple sclerosis

(2012) Graham R. Campbell et al.   CURRENT OPINION IN NEUROLOGY

CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation

(2012) Markus C Kowarik et al.   Journal of Neuroinflammation

Acute Transverse Myelitis: Demyelinating, Inflammatory, and Infectious Myelopathies

(2012) Timothy West et al.   SEMINARS IN NEUROLOGY

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis

(2011) Jessica L. Zambonin et al.   BRAIN

Efficient inducible Pan-neuronal cre-mediated recombination in SLICK-H transgenic mice

(2011) Victoria Heimer-McGinn et al.   GENESIS

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

(2010) D. Gris et al.   JOURNAL OF IMMUNOLOGY

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

(2010) Jami Bennett et al.   JOURNAL OF NEUROIMMUNOLOGY

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

Motor coordination impairment in aged heterozygous rolling Nagoya, Cav2.1 mutant mice

(2009) Eiki Takahashi et al.   BRAIN RESEARCH

Axonal degeneration in multiple sclerosis: The mitochondrial hypothesis

(2009) Kimmy G. Su et al.   Current Neurology and Neuroscience Reports

Enhanced number and activity of mitochondria in multiple sclerosis lesions

(2009) Maarten E Witte et al.   JOURNAL OF PATHOLOGY

Long-Term Follow-up of Arthroscopic Treatment of Lateral Epicondylitis

(2008) Champ L. Baker et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice

(2008) Paul Young et al.   NATURE NEUROSCIENCE