Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

Searching for a mitochondrial root to the decline in muscle function with ageing

(2018) Marta Gonzalez-Freire et al.   Journal of Cachexia Sarcopenia and Muscle

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass

(2018) Bumsoo Ahn et al.   Redox Biology

Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness

(2018) Rizwan Qaisar et al.   Journal of Cachexia Sarcopenia and Muscle

Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure

(2018) Masaya Tsuda et al.   Journal of Cachexia Sarcopenia and Muscle

Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy

(2017) Dustin R. Masser et al.   JOURNAL OF NEUROCHEMISTRY

Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing

(2017) Aphrodite Vasilaki et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

(2017) Ryan M. Morrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour-bearing mice

(2017) Jacob L. Brown et al.   Journal of Cachexia Sarcopenia and Muscle

Redox homeostasis and age-related deficits in neuromuscular integrity and function

(2017) Giorgos K. Sakellariou et al.   Journal of Cachexia Sarcopenia and Muscle

Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue

(2017) Kerstin Boengler et al.   Journal of Cachexia Sarcopenia and Muscle

Ethical guidelines for publishing in the journal of cachexia, sarcopenia and muscle: update 2017

(2017) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

The breaking and making of healthy adult human skeletal muscle in vivo

(2017) Abigail L. Mackey et al.   Skeletal Muscle

Loss of the antioxidant enzyme CuZnSOD (Sod1) mimics an age-related increase in absolute mitochondrial DNA copy number in the skeletal muscle

(2016) Dustin R. Masser et al.   AGE

New roles for mitochondrial proteases in health, ageing and disease

(2015) Pedro M. Quirós et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial respiration and redox coupling in articular chondrocytes

(2015) Rachel S Lane et al.   ARTHRITIS RESEARCH & THERAPY

Peripheral nerve and neuromuscular junction pathology in Pompe disease

(2014) Darin J. Falk et al.   HUMAN MOLECULAR GENETICS

The Lack of CuZnSOD Leads to Impaired Neurotransmitter Release, Neuromuscular Junction Destabilization and Reduced Muscle Strength in Mice

(2014) Yun Shi et al.   PLoS One

Myofiber branching rather than myofiber hyperplasia contributes to muscle hypertrophy in mdx mice

(2014) Rachel M Faber et al.   Skeletal Muscle

Diaphragm and ventilatory dysfunction during cancer cachexia

(2013) Brandon M. Roberts et al.   FASEB JOURNAL

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

(2013) Yiqiang Zhang et al.   FASEB JOURNAL

Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice

(2013) Giorgos K. Sakellariou et al.   FASEB JOURNAL

Glutathionylation of α-ketoglutarate dehydrogenase: The chemical nature and relative susceptibility of the cofactor lipoic acid to modification

(2013) Aaron L. McLain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

(2012) Young C. Jang et al.   AGING CELL

The Paradox of Muscle Hypertrophy in Muscular Dystrophy

(2012) Joe N. Kornegay et al.   Physical Medicine and Rehabilitation Clinics of North America

MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging

(2011) Michael S. Lustgarten et al.   AGING CELL

Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation

(2011) Lisa M. Larkin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification of Mitochondrial Electron Transport Chain-Mediated NADH Radical Formation by EPR Spin-Trapping Techniques

(2011) Satoshi Matsuzaki et al.   BIOCHEMISTRY

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling

(2010) Benjamin S. Avner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative stress in skeletal muscle causes severe disturbance of exercise activity without muscle atrophy

(2010) Hirotomo Kuwahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-Ketoglutarate dehydrogenase: A mitochondrial redox sensor

(2010) Aaron L. McLain et al.   FREE RADICAL RESEARCH

Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity

(2009) Michael S. Lustgarten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Malformed mdx myofibers have normal cytoskeletal architecture yet altered EC coupling and stress-induced Ca2+ signaling

(2009) Richard M. Lovering et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protective effects of Hsp70 on the structure and function of SERCA2a expressed in HEK-293 cells during heat stress

(2009) M. H. Fu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alpha II-Spectrin Breakdown Products Serve as Novel Markers of Brain Injury Severity in a Canine Model of Hypothermic Circulatory Arrest

(2009) Eric S. Weiss et al.   ANNALS OF THORACIC SURGERY

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

(2009) Youngmok C. Jang et al.   FASEB JOURNAL

Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy

(2008) Dennis R. Claflin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calpain-1 is required for hydrogen peroxide-induced myotube atrophy

(2008) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Resistance to Ca2+-induced opening of the permeability transition pore differs in mitochondria from glycolytic and oxidative muscles

(2008) Martin Picard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

(2008) Florian L. Muller et al.   BIOCHEMICAL JOURNAL

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

(2008) Andrey V Kuznetsov et al.   Nature Protocols

Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production

(2008) Scott K. Powers et al.   PHYSIOLOGICAL REVIEWS

Protein Nitration in Placenta – Functional Significance

(2008) R.P. Webster et al.   PLACENTA