Molecular changes associated with spinal cord aging

Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment with Rapamycin or Rapamycin with Metformin

(2019) Justin J Reid et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Muscle‐specific changes in protein synthesis with aging and reloading after disuse atrophy

(2019) Benjamin F. Miller et al.   Journal of Cachexia Sarcopenia and Muscle

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

(2019) Slaven Stekovic et al.   Cell Metabolism

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

(2019) Csaba Cserép et al.   SCIENCE

Lumbar spinal cord microglia exhibited increased activation in aging dogs compared with young adult dogs

(2019) Christine M. Toedebusch et al.   GeroScience

α-Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice

(2018) Nicholas Maxwell et al.   AGING CELL

Ageing: Is there a role for arachidonic acid and other bioactive lipids? A review

(2018) Undurti N. Das   Journal of Advanced Research

Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health

(2018) Ashley Gillon et al.   GeroScience

MMP-12, a Promising Therapeutic Target for Neurological Diseases

(2017) Bharath Chelluboina et al.   MOLECULAR NEUROBIOLOGY

Transcriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord

(2017) William Galbavy et al.   Immunity & Ageing

Energy metabolism and inflammation in brain aging and Alzheimer’s disease

(2016) Fei Yin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Perturbed cholesterol homeostasis in aging spinal cord

(2016) Gemma M. Parkinson et al.   NEUROBIOLOGY OF AGING

Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity

(2015) Joshua C. Drake et al.   AGING CELL

Sod1 gene ablation in adult mice leads to physiological changes at the neuromuscular junction similar to changes that occur in old wild-type mice

(2015) Maxim V. Ivannikov et al.   FREE RADICAL BIOLOGY AND MEDICINE

Moving targets: Emerging roles for MMPs in cancer progression and metastasis

(2015) Gemma Shay et al.   MATRIX BIOLOGY

Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics

(2015) Harris Bell-Temin et al.   MOLECULAR & CELLULAR PROTEOMICS

Novel Insights into NeuN: from Neuronal Marker to Splicing Regulator

(2015) Wei Duan et al.   MOLECULAR NEUROBIOLOGY

Matrix Metalloproteinase-12 Induces Blood–Brain Barrier Damage After Focal Cerebral Ischemia

(2015) Bharath Chelluboina et al.   STROKE

Serum Soluble Adhesion Molecules and Markers of Systemic Inflammation in Elderly Diabetic Patients with Mild Cognitive Impairment and Depressive Symptoms

(2015) Malgorzata Gorska-Ciebiada et al.   Biomed Research International

Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage

(2015) Bharath Chelluboina et al.   Scientific Reports

Peripheral nerve and neuromuscular junction pathology in Pompe disease

(2014) Darin J. Falk et al.   HUMAN MOLECULAR GENETICS

Changes in mitochondrial bioenergetics in the brain versus spinal cord become more apparent with age

(2014) Heather M. Yonutas et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice

(2014) Michael E. Walsh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS

(2013) FANG XIE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice

(2013) Joshua C. Drake et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Decreased NAA in Gray Matter is Correlated with Decreased Availability of Acetate in White Matter in Postmortem Multiple Sclerosis Cortex

(2013) S. Li et al.   NEUROCHEMICAL RESEARCH

Alterations of brain eicosanoid synthetic pathway in multiple sclerosis and in animal models of demyelination: Role of cyclooxygenase-2

(2013) Sara Palumbo et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

(2012) Young C. Jang et al.   AGING CELL

The immunology of neurodegeneration

(2012) Eva Czirr et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix metalloproteinase-12 contributes to neuroinflammation in the aged brain

(2012) Yang Liu et al.   NEUROBIOLOGY OF AGING

A perspective on the determination of mitochondrial biogenesis

(2011) Benjamin F. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Matrix metalloproteinases and soluble Fas/FasL system as novel regulators of apoptosis in children and young adults on chronic dialysis

(2011) Kinga Musiał et al.   APOPTOSIS

1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord

(2011) Matthias Erschbamer et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Age-associated alterations of the neuromuscular junction

(2010) Youngmok C. Jang et al.   EXPERIMENTAL GERONTOLOGY

Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells

(2010) Sophie Grimal et al.   GLIA

Nrf2 activity is lost in the spinal cord and its astrocytes of aged mice

(2009) Weisong Duan et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress

(2008) Nathan L. Sparkman et al.   NEUROIMMUNOMODULATION