Tumorigenesis Mechanisms Found in Hereditary Renal Cell Carcinoma: A Review

Cost-effectiveness model of renal cell carcinoma (RCC) surveillance in hereditary leiomyomatosis and renal cell carcinoma (HLRCC)

(2022) Alexander J Thompson et al.   JOURNAL OF MEDICAL GENETICS

Kidney Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology

(2022) Robert J. Motzer et al.   Journal of the National Comprehensive Cancer Network

BAP1 promotes the repair of UV-induced DNA damage via PARP1-mediated recruitment to damage sites and control of activity and stability

(2022) Shin-Ai Lee et al.   CELL DEATH AND DIFFERENTIATION

Elongin C (ELOC/TCEB1)-associated von Hippel–Lindau disease

(2022) Avgi Andreou et al.   HUMAN MOLECULAR GENETICS

Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations

(2022) Michele Carbone et al.   Journal of Thoracic Oncology

Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis

(2022) Jing Yang et al.   Bioengineered

Models of Renal Cell Carcinoma Used to Investigate Molecular Mechanisms and Develop New Therapeutics

(2022) Daniel D. Shapiro et al.   Frontiers in Oncology

VHL mosaicism: the added value of multi-tissue analysis

(2022) Leslie E. Oldfield et al.   npj Genomic Medicine

FDA Approval Summary: Belzutifan for von Hippel-Lindau Disease–Associated Tumors

(2022) Jaleh Fallah et al.   CLINICAL CANCER RESEARCH

von Hippel-Lindau disease: Updated guideline for diagnosis and surveillance

(2022) Marie Louise M Binderup et al.   European Journal of Medical Genetics

The 2022 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours

(2022) Holger Moch et al.   EUROPEAN UROLOGY

Genomic Profiling and Response to Immune Checkpoint Inhibition plus Tyrosine Kinase Inhibition in FH-Deficient Renal Cell Carcinoma

(2022) Yunze Xu et al.   EUROPEAN UROLOGY

Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline

(2022) W. Kimryn Rathmell et al.   JOURNAL OF CLINICAL ONCOLOGY

Co-occurrence of VHL and SDHA Pathogenic Variants: A Case Report

(2022) Moon Ley Tung et al.   Frontiers in Oncology

Roles and mechanisms of BAP1 deubiquitinase in tumor suppression

(2021) Louis Masclef et al.   CELL DEATH AND DIFFERENTIATION

Relationship between visceral adipose tissue and genetic mutations (VHL and KDM5C) in clear cell renal cell carcinoma

(2021) Federico Greco et al.   Radiologia Medica

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer

(2021) Daniel R. Crooks et al.   Science Signaling

Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines

(2021) Youfeng Yang et al.   GENES CHROMOSOMES & CANCER

Comprehensive characterization of Alu ‐mediated breakpoints in germline VHL gene deletions and rearrangements in patients from 71 VHL families

(2021) Cathy D. Vocke et al.   HUMAN MUTATION

Imaging features of fumarate hydratase-deficient renal cell carcinomas: a retrospective study

(2021) Ines Nikolovski et al.   CANCER IMAGING

Succinylation Regulators Promote Clear Cell Renal Cell Carcinoma by Immune Regulation and RNA N6-Methyladenosine Methylation

(2021) Wenqing Lu et al.   Frontiers in Cell and Developmental Biology

Reoperative Partial Nephrectomy: Does Previous Surgical Footprint Impact Outcomes?

(2021) Sandeep Gurram et al.   JOURNAL OF UROLOGY

X-Capsular Incision for Tumor Enucleation (X-CITE)-Technique: A method to maximize renal parenchymal preservation for completely endophytic renal tumors

(2021) Amir H. Lebastchi et al.   UROLOGY

Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients

(2021) Nicholas W. Bateman et al.   Scientific Reports

Improving Renal Tumor Biopsy Prognostication With BAP1 Analyses

(2021) Payal Kapur et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Kidney cancer: from genes to therapy

(2021) Bradley R. Webster et al.   CURRENT PROBLEMS IN CANCER

Phase 2 study of belzutifan (MK-6482), an oral hypoxia-inducible factor 2α (HIF-2α) inhibitor, for Von Hippel-Lindau (VHL) disease-associated clear cell renal cell carcinoma (ccRCC).

(2021) Ramaprasad Srinivasan et al.   JOURNAL OF CLINICAL ONCOLOGY

Renal Neoplasia in Tuberous Sclerosis: A Study of 41 Patients

(2021) Sounak Gupta et al.   MAYO CLINIC PROCEEDINGS

Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer

(2021) Ritesh K. Aggarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Birt-Hogg-Dubé Syndrome and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome: An Effective Multidisciplinary Approach to Hereditary Renal Cancer Predisposing Syndromes

(2021) Mohammad Al-Shinnag et al.   Frontiers in Oncology

Novel germline MET pathogenic variants in French patients with papillary renal cell carcinomas type I

(2021) Molka Sebai et al.   HUMAN MUTATION

Clinical characteristics and risk factors for survival in affected offspring of von Hippel-Lindau disease patients

(2021) Kenan Zhang et al.   JOURNAL OF MEDICAL GENETICS

SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effect

(2021) Liu Yihan et al.   Journal of Translational Medicine

Belzutifan for Renal Cell Carcinoma in von Hippel–Lindau Disease

(2021) Eric Jonasch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renal Cell Carcinoma in Tuberous Sclerosis Complex

(2021) Elizabeth P. Henske et al.   Genes

Complete Response of Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC)-Associated Renal Cell Carcinoma to Pembrolizumab Immunotherapy: A Case Report

(2021) Tao Wang et al.   Frontiers in Oncology

Birt-Hogg-Dubé Syndrome

(2021) Subha Ghosh et al.   RADIOLOGY

Growth Rates of Genetically Defined Renal Tumors: Implications for Active Surveillance and Intervention

(2020) Mark W. Ball et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-term Functional and Oncologic Outcomes of Partial Adrenalectomy for Pheochromocytoma

(2020) Patrick T. Gomella et al.   UROLOGY

First-line pembrolizumab (pembro) monotherapy in advanced non-clear cell renal cell carcinoma (nccRCC): Updated follow-up for KEYNOTE-427 cohort B.

(2020) Jae-Lyun Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Efficacy of Savolitinib vs Sunitinib in Patients With MET-Driven Papillary Renal Cell Carcinoma

(2020) Toni K. Choueiri et al.   JAMA Oncology

Nephron-Sparing Surgery for Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical T1 Stage: A Multicenter Study in China

(2020) Ning Liu et al.   ANNALS OF SURGICAL ONCOLOGY

Complete response of hereditary leiomyomatosis and renal cell cancer (HLRCC)-associated renal cell carcinoma to nivolumab and ipilimumab combination immunotherapy by: a case report

(2020) Yasuhiro Iribe et al.   Familial Cancer

A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome

(2020) Gennaro Napolitano et al.   NATURE

Oncometabolites suppress DNA repair by disrupting local chromatin signalling

(2020) Parker L. Sulkowski et al.   NATURE

Role of [68Ga]DOTANOC PET/computed tomography and [131I]MIBG scintigraphy in the management of patients with pheochromocytoma and paraganglioma

(2020) Deepa Singh et al.   NUCLEAR MEDICINE COMMUNICATIONS

Von Hippel-Lindau Disease: Current Challenges and Future Prospects

(2020) Sven Gläsker et al.   OncoTargets and Therapy

NCCN Guidelines Insights: Kidney Cancer, Version 1.2021

(2020) Robert J. Motzer et al.   Journal of the National Comprehensive Cancer Network

Systematic Proteome and Lysine Succinylome Analysis Reveals the Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Cancer

(2020) Zhenchang Guo et al.   MOLECULAR & CELLULAR PROTEOMICS

Evaluation, diagnosis and surveillance of renal masses in the setting of VHL disease

(2020) Jad Chahoud et al.   WORLD JOURNAL OF UROLOGY

Long term outcomes for patients with von Hippel-Lindau and Pheochromocytoma: defining the role of active surveillance

(2020) Thomas Sanford et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Clinical and Molecular Characterization of Microphthalmia-associated Transcription Factor (MITF)-related Renal Cell Carcinoma

(2020) Martin Lang et al.   UROLOGY

C-Met as a Key Factor Responsible for Sustaining Undifferentiated Phenotype and Therapy Resistance in Renal Carcinomas

(2019) Paulina Marona et al.   Cells

A comparison of outcomes for standard and multiplex partial nephrectomy in a solitary kidney: The National Cancer Institute experience

(2019) Joseph A. Baiocco et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

A phase II study investigating the safety and efficacy of savolitinib and durvalumab in metastatic papillary renal cancer (CALYPSO).

(2019) Thomas Powles et al.   JOURNAL OF CLINICAL ONCOLOGY

Inherited kidney cancer syndromes

(2019) Mark W. Ball et al.   CURRENT OPINION IN UROLOGY

SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis

(2019) Yuanzhen Ma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Familial Kidney Cancer: Implications of New Syndromes and Molecular Insights

(2019) Maria I. Carlo et al.   EUROPEAN UROLOGY

The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications

(2019) W. Marston Linehan et al.   Nature Reviews Urology

Oncometabolites in renal cancer

(2019) Cissy Yong et al.   Nature Reviews Nephrology

Identification and Validation of Radiographic Enhancement for Reliable Differentiation of CD117(+) Benign Renal Oncocytoma and Chromophobe Renal Cell Carcinoma

(2018) Jay Amin et al.   CLINICAL CANCER RESEARCH

Germline BAP1 -positive patients: the dilemmas of cancer surveillance and a proposed interdisciplinary consensus monitoring strategy

(2018) Phoebe Star et al.   EUROPEAN JOURNAL OF CANCER

FLCN : The causative gene for Birt-Hogg-Dubé syndrome

(2018) Laura S. Schmidt et al.   GENE

Genotype and phenotype correlation in von Hippel–Lindau disease based on alteration of the HIF-α binding site in VHL protein

(2018) Sheng-Jie Liu et al.   GENETICS IN MEDICINE

Renal progression factors in young patients with tuberous sclerosis complex: a retrospective cohort study

(2018) Peter Janssens et al.   PEDIATRIC NEPHROLOGY

Hereditary renal cell carcinoma syndromes: diagnosis, surveillance and management

(2018) Eamonn R. Maher   WORLD JOURNAL OF UROLOGY

OUP accepted manuscript

(2018)   JNCI-Journal of the National Cancer Institute

Angiomyolipoma rebound tumor growth after discontinuation of everolimus in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis

(2018) John J. Bissler et al.   PLoS One

Cabozantinib for the treatment of patients with metastatic non-clear cell renal cell carcinoma: A retrospective analysis

(2018) Matthew T. Campbell et al.   EUROPEAN JOURNAL OF CANCER

SDH-deficient renal cell carcinoma – clinical, pathologic and genetic correlates: a case report

(2018) Ravi Kumar et al.   BMC Urology

Crizotinib achieves long-lasting disease control in advanced papillary renal-cell carcinoma type 1 patients with MET mutations or amplification. EORTC 90101 CREATE trial

(2017) Patrick Schöffski et al.   EUROPEAN JOURNAL OF CANCER

Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer

(2017) Toni K. Choueiri et al.   JOURNAL OF CLINICAL ONCOLOGY

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

(2017) Angela Bononi et al.   NATURE

Mitochondrial Complex II: At the Crossroads

(2017) Ayenachew Bezawork-Geleta et al.   TRENDS IN BIOCHEMICAL SCIENCES

Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein

(2017) Laura A. Laviolette et al.   Nature Communications

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Multiplex Partial Nephrectomy, Repeat Partial Nephrectomy, and Salvage Partial Nephrectomy Remain the Primary Treatment in Multifocal and Hereditary Kidney Cancer

(2017) Joseph A. Baiocco et al.   Frontiers in Oncology

The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours

(2016) Holger Moch et al.   EUROPEAN UROLOGY

Repeat Robotic Partial Nephrectomy: Characteristics, Complications, and Renal Functional Outcomes

(2016) Matthew J. Watson et al.   JOURNAL OF ENDOUROLOGY

Clear Cell Renal Cell Carcinoma Subtypes Identified by BAP1 and PBRM1 Expression

(2016) Richard W. Joseph et al.   JOURNAL OF UROLOGY

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker

(2016) Stephan Macher-Goeppinger et al.   Oncotarget

New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease

(2015) R. Srinivasan et al.   CLINICAL CANCER RESEARCH

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer

(2015) Salima Daou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EMERGE: A Randomized Phase II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Advanced Glycoprotein NMB–Expressing Breast Cancer

(2015) Denise A. Yardley et al.   JOURNAL OF CLINICAL ONCOLOGY

Mammalian target of rapamycin and tuberous sclerosis complex

(2015) Mari Wataya-Kaneda   JOURNAL OF DERMATOLOGICAL SCIENCE

Disruption of tubular Flcn expression as a mouse model for renal tumor induction

(2015) Jindong Chen et al.   KIDNEY INTERNATIONAL

Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy

(2015) Claudia Wellbrock et al.   Pigment Cell & Melanoma Research

MiT family translocation renal cell carcinoma

(2015) Pedram Argani   SEMINARS IN DIAGNOSTIC PATHOLOGY

Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma

(2014) Anthony J. Gill et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome–associated Renal Cancer

(2014) Ying-Bei Chen et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Renal Cell Carcinoma in Tuberous Sclerosis Complex

(2014) Ping Yang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Tuberous Sclerosis–associated Renal Cell Carcinoma

(2014) Juan Guo et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Nephron-sparing surgery for multifocal and hereditary renal tumors

(2014) Adam R. Metwalli et al.   CURRENT OPINION IN UROLOGY

5 Mechanism based targeted therapy for hereditary leiomyomatosis and renal cell cancer (HLRCC) and sporadic papillary renal cell carcinoma: interim results from a phase 2 study of bevacizumab and erlotinib

(2014) R. Srinivasan et al.   EUROPEAN JOURNAL OF CANCER

Hereditary leiomyomatosis and renal cell cancer (HLRCC): renal cancer risk, surveillance and treatment

(2014) Fred H. Menko et al.   Familial Cancer

Phase I/II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Patients With Advanced Melanoma

(2014) Patrick A. Ott et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase I/II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Patients With Locally Advanced or Metastatic Breast Cancer

(2014) Johanna Bendell et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers

(2014) Eric C. Kauffman et al.   Nature Reviews Urology

Topical Rapamycin as a Treatment for Fibrofolliculomas in Birt-Hogg-Dubé Syndrome: A Double-Blind Placebo-Controlled Randomized Split-Face Trial

(2014) Lieke M. C. Gijezen et al.   PLoS One

Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK

(2014) Elena A. Goncharova et al.   Cell Reports

Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma

(2013) Richard W. Joseph et al.   CANCER

Molecular Pathways: Fumarate Hydratase-Deficient Kidney Cancer--Targeting the Warburg Effect in Cancer

(2013) W. M. Linehan et al.   CLINICAL CANCER RESEARCH

Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma

(2013) L. Goyal et al.   CLINICAL CANCER RESEARCH

Diagnosis and management of BHD-associated kidney cancer

(2013) Lambros Stamatakis et al.   Familial Cancer

Birt–Hogg–Dubé syndrome is a novel ciliopathy

(2013) Monique N.H. Luijten et al.   HUMAN MOLECULAR GENETICS

Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases

(2013) Constance S. Petit et al.   JOURNAL OF CELL BIOLOGY

FamilialSDHAMutation Associated With Pituitary Adenoma and Pheochromocytoma/Paraganglioma

(2013) Trisha Dwight et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial

(2013) John J Bissler et al.   LANCET

A Novel Germline Mutation in BAP1 Predisposes to Familial Clear-Cell Renal Cell Carcinoma

(2013) M. N. Farley et al.   MOLECULAR CANCER RESEARCH

Arsenic in drinking water and renal cancers in rural Bangladesh

(2013) MG Mostafa et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Tuberous Sclerosis Complex Surveillance and Management: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference

(2013) Darcy A. Krueger et al.   PEDIATRIC NEUROLOGY

Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

(2013) H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic basis of kidney cancer: Role of genomics for the development of disease-based therapeutics

(2012) W. M. Linehan   GENOME RESEARCH

HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells

(2012) ATSUSHI MATSUMURA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Phase II and Biomarker Study of the Dual MET/VEGFR2 Inhibitor Foretinib in Patients With Papillary Renal Cell Carcinoma

(2012) Toni K. Choueiri et al.   JOURNAL OF CLINICAL ONCOLOGY

Succinate Dehydrogenase Kidney Cancer: An Aggressive Example of the Warburg Effect in Cancer

(2012) Christopher J. Ricketts et al.   JOURNAL OF UROLOGY

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

The VHL/HIF axis in clear cell renal carcinoma

(2012) Chuan Shen et al.   SEMINARS IN CANCER BIOLOGY

Environmental and modifiable risk factors in renal cell carcinoma

(2012) Neema Navai et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Succinate Dehydrogenase-Deficient GISTs

(2011) Markku Miettinen et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SDH mutations in cancer

(2011) Chiara Bardella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Renal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families

(2011) A C Houweling et al.   BRITISH JOURNAL OF CANCER

von Hippel–Lindau disease: A clinical and scientific review

(2011) Eamonn R Maher et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Novel FH mutations in families with hereditary leiomyomatosis and renal cell cancer (HLRCC) and patients with isolated type 2 papillary renal cell carcinoma

(2011) B. Gardie et al.   JOURNAL OF MEDICAL GENETICS

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

(2011) Chiara Bardella et al.   JOURNAL OF PATHOLOGY

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

(2011) Corine Bertolotto et al.   NATURE

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

c-MET as a potential therapeutic target and biomarker in cancer

(2011) J. Rafael Sierra et al.   Therapeutic Advances in Medical Oncology

Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis

(2010) DL Smit et al.   CLINICAL GENETICS

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

(2010) R S Preston et al.   ONCOGENE

Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization

(2010) Seung-Beom Hong et al.   PLoS One

Review: Updates on novel therapies for metastatic renal cell carcinoma

(2010) Kevin D. Courtney et al.   Therapeutic Advances in Medical Oncology

UOK 262 cell line, fumarate hydratase deficient (FH−/FH−) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

(2009) Youfeng Yang et al.   CANCER GENETICS AND CYTOGENETICS

Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney

(2009) R. Beroukhim et al.   CANCER RESEARCH

Initial Experience With Robot Assisted Partial Nephrectomy for Multiple Renal Masses

(2009) Ronald Boris et al.   JOURNAL OF UROLOGY

Birt-Hogg-Dubé syndrome: diagnosis and management

(2009) Fred H Menko et al.   LANCET ONCOLOGY

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

Kidney-Targeted Birt-Hogg-Dube Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys

(2008) M. Baba et al.   JNCI-Journal of the National Cancer Institute

Gpnmbis a melanoblast-expressed, MITF-dependent gene

(2008) Stacie K. Loftus et al.   Pigment Cell & Melanoma Research

Changing Trends in Presentation, Diagnosis and Management of Renal Angiomyolipoma: Comparison of Sporadic and Tuberous Sclerosis Complex-associated Forms

(2008) Raouf M. Seyam et al.   UROLOGY

Birt-Hogg-Dubé Syndrome: Clinical and Genetic Studies of 20 Families

(2007) Edward M. Leter et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Salvage Partial Nephrectomy for Hereditary Renal Cancer: Feasibility and Outcomes

(2007) Gennady Bratslavsky et al.   JOURNAL OF UROLOGY