Bear bile powder ameliorates type 2 diabetes via modulation of metabolic profiles, gut microbiota, and metabolites

Heat‐treated adzuki bean protein hydrolysates reduce obesity in mice fed a high‐fat diet via remodeling gut microbiota and improving metabolic function

(2022) Qingyu Zhao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease

(2022) Pedro R. Pereira et al.   MEDICINAL RESEARCH REVIEWS

Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice

(2022) Aoxiang Zhuge et al.   Microbiology Spectrum

Interactive Relationships between Intestinal Flora and Bile Acids

(2022) Xiaohua Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The burden and risks of emerging complications of diabetes mellitus

(2022) Dunya Tomic et al.   Nature Reviews Endocrinology

Central and peripheral regulations mediated by short-chain fatty acids on energy homeostasis

(2022) Pei Luo et al.   Translational Research

Combining fecal microbiome and metabolomics to reveal the disturbance of gut microbiota in liver injury and the therapeutic mechanism of shaoyao gancao decoction

(2022) Jingwei Li et al.   Frontiers in Pharmacology

Selenium Deficiency Leads to Inflammation, Autophagy, Endoplasmic Reticulum Stress, Apoptosis and Contraction Abnormalities via Affecting Intestinal Flora in Intestinal Smooth Muscle of Mice

(2022) Fuhan Wang et al.   Frontiers in Immunology

Taurine inhibits hydrogen peroxide-induced oxidative stress, inflammatory response and apoptosis in liver of Monopterus albus

(2022) Yong Shi et al.   FISH & SHELLFISH IMMUNOLOGY

In-depth investigation of the hypoglycemic mechanism of Morchella importuna polysaccharide via metabonomics combined with 16S rRNA sequencing

(2022) Xu Pan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

N‐Acetylserotonin is an oxidation‐responsive activator of Nrf2 ameliorating colitis in rats

(2022) Changyu Kang et al.   JOURNAL OF PINEAL RESEARCH

Tauroursodeoxycholic acid functions as a critical effector mediating insulin sensitization of metformin in obese mice

(2022) Ya Zhang et al.   Redox Biology

Disruption of adipocyte YAP improves glucose homeostasis in mice and decreases adipose tissue fibrosis

(2022) Daniel J. Han et al.   Molecular Metabolism

Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes

(2021) Richard R. Rodrigues et al.   Nature Communications

Plant Extracts for Type 2 Diabetes: From Traditional Medicine to Modern Drug Discovery

(2021) Jinjoo Lee et al.   Antioxidants

The promise of the gut microbiome as part of individualized treatment strategies

(2021) Daniel A. Schupack et al.   Nature Reviews Gastroenterology & Hepatology

Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

(2021) Thi Phuong Nam Bui et al.   Nature Communications

Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity

(2021) Zhangling Chen et al.   JAMA Network Open

Cultured bear bile powder ameliorates acute liver injury in cholestatic mice via inhibition of hepatic inflammation and apoptosis

(2021) Jingyi Cai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Oral gavage of nano-encapsulated conjugated acrylic acid-bile acid formulation in type 1 diabetes altered pharmacological profile of bile acids, and improved glycaemia and suppressed inflammation

(2020) Armin Mooranian et al.   Pharmacological Reports

An integrated microbiome and metabolomic analysis identifies immunoenhancing features of Ganoderma lucidum spores oil in mice

(2020) Xu Wu et al.   PHARMACOLOGICAL RESEARCH

Hypoglycemic mechanism of polysaccharide from Cyclocarya paliurus leaves in type 2 diabetic rats by gut microbiota and host metabolism alteration

(2020) Qiqiong Li et al.   Science China-Life Sciences

The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System

(2020) Gholamreza Daryabor et al.   Frontiers in Immunology

Analysis of serum lysophosphatidylethanolamine levels in patients with non-alcoholic fatty liver disease by liquid chromatography-tandem mass spectrometry

(2020) Yusuke Yamamoto et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Identification of gut microbiota and microbial metabolites regulated by an antimicrobial peptide lipocalin 2 in high fat diet-induced obesity

(2020) Xiaoxue Qiu et al.   INTERNATIONAL JOURNAL OF OBESITY

Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production

(2019) Zhuo Mao et al.   DIABETES

Trimethylamine N ‐Oxide Aggravates Liver Steatosis through Modulation of Bile Acid Metabolism and Inhibition of Farnesoid X Receptor Signaling in Nonalcoholic Fatty Liver Disease

(2019) Xuying Tan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats

(2019) Jin-Wang Li et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

(2019) Sifan Chen et al.   Cell Metabolism

Probiotics for the treatment of type 2 diabetes: A review of randomized controlled trials

(2019) Kelly A. Tiderencel et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Functions and regulation of T cell-derived interleukin-10

(2019) Christian Neumann et al.   SEMINARS IN IMMUNOLOGY

Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice

(2019) Shaohua Wang et al.   GeroScience

Anaphylatoxin C5a induces inflammation and reduces insulin sensitivity by activating TLR4/NF-kB/PI3K signaling pathway in 3T3-L1 adipocytes

(2018) Xin-Yan Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Antihyperlipidemic and hepatoprotective activities of polysaccharide fraction from Cyclocarya paliurus in high-fat emulsion-induced hyperlipidaemic mice

(2018) Zhanwei Yang et al.   CARBOHYDRATE POLYMERS

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

(2017) Zhuang Li et al.   GUT

Relationship between alanine aminotransferase levels and type 2 diabetes mellitus in the general Chinese population

(2017) Aihua Liu et al.   Journal of Diabetes

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis

(2016) Jihwa Chung et al.   PLoS One

Functional Role of Serotonin in Insulin Secretion in a Diet-Induced Insulin-Resistant State

(2015) Kyuho Kim et al.   ENDOCRINOLOGY

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

(2014) Annick V. Hartstra et al.   DIABETES CARE

The role of phospholipids in the biological activity and structure of the endoplasmic reticulum

(2013) Thomas A. Lagace et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The association of specific metabolites of lipid metabolism with markers of oxidative stress, inflammation and arterial stiffness in men with newly diagnosed type 2 diabetes

(2011) Chang Young Ha et al.   CLINICAL ENDOCRINOLOGY

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity