Natural bioactive compounds-doxorubicin combinations targeting topoisomerase II-alpha: Anticancer efficacy and safety

Amalgamation of Nanotechnology for Delivery of Bioactive Constituents in Solid Tumors

(2022) Rabea Parveen et al.   Current Drug Delivery

Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, <i>in Vitro</i> and <i>in Vivo</i> Evaluation

(2022) Linghui Zou et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Antioxidative properties of phenolic compounds and their effect on oxidative stress induced by severe physical exercise

(2022) Joanna Kruk et al.   Journal of Physiological Sciences

Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells

(2021) Hiroaki Eguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine ameliorates doxorubicin-induced cognitive impairment (chemobrain) in rats

(2021) Fatma H. Shaker et al.   LIFE SCIENCES

Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro

(2021) Xiaoping Wang et al.   MOLECULES

Natural products in drug discovery: advances and opportunities

(2021) Atanas G. Atanasov et al.   NATURE REVIEWS DRUG DISCOVERY

Antioxidant and Anti-Inflammatory Effects of Crocin Ameliorate Doxorubicin-Induced Nephrotoxicity in Rats

(2021) Mona A. Hussain et al.   Oxidative Medicine and Cellular Longevity

Epigenetic immunomodulatory effect of eugenol and astaxanthin on doxorubicin cytotoxicity in hormonal positive breast Cancer cells

(2021) Mariam A. Fouad et al.   BMC Pharmacology & Toxicology

Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis

(2021) SE Owumi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats

(2021) Sara Asaad Abdulkareem Aljumaily et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo

(2021) Sixue Tang et al.   JOURNAL OF FOOD BIOCHEMISTRY

Thymoquinone and its nanoformulation attenuate colorectal and breast cancers and alleviate doxorubicin-induced cardiotoxicity

(2021) Ali H El-Far et al.   Nanomedicine

Betulinic Acid–Doxorubicin-Drug Combination Induced Apoptotic Death via ROS Stimulation in a Relapsed AML MOLM-13 Cell Model

(2021) Milan Vu et al.   Antioxidants

Nanonutraceuticals: Anti-Cancer Activity and Improved Safety of Chemotherapy by Costunolide and Its Nanoformulation against Colon and Breast Cancer

(2021) Ali H. EI-Far et al.   Biomedicines

Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways

(2021) Shaimaa S. Ibrahim et al.   NEUROPHARMACOLOGY

The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats

(2021) Ghadha Ibrahim Fouad et al.   TISSUE & CELL

Doxorubicin‐induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2

(2020) Jingang Hou et al.   PHYTOTHERAPY RESEARCH

Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer

(2020) Ye Wang et al.   OncoTargets and Therapy

Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression

(2020) Yue Yang et al.   Biomed Research International

Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin

(2020) Shuhui Zhang et al.   Frontiers in Pharmacology

Luteolin Attenuates Doxorubicin-Induced Cardiotoxicity Through Promoting Mitochondrial Autophagy

(2020) Haixia Xu et al.   Frontiers in Physiology

Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma

(2020) Zhuo Yu et al.   ACS Nano

Attenuation of doxorubicin-induced cardiotoxicity by cryptotanshinone detected through association analysis of transcriptomic profiling and KEGG pathway

(2020) Le Li et al.   Aging-US

Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles

(2020) Shuo Liu et al.   MOLECULAR PHARMACEUTICS

Asiatic Acid Protects against Doxorubicin-Induced Cardiotoxicity in Mice

(2020) Xiaoping Hu et al.   Oxidative Medicine and Cellular Longevity

Naringenin Regulates Doxorubicin-Induced Liver Dysfunction: Impact on Oxidative Stress and Inflammation

(2020) Adil Farooq Wali et al.   Plants-Basel

Protective role of chrysin on doxorubicin‐induced oxidative stress and DNA damage in rat testes

(2020) Saadet Belhan et al.   ANDROLOGIA

Hepatoprotective Role of Berberine on Doxorubicin Induced Hepatotoxici-ty – Involvement of Cyp

(2020) Bao Sun et al.   CURRENT DRUG METABOLISM

Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro

(2020) Xi Chu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ultrasound Combined with Core Cross-Linked Nanosystem for Enhancing Penetration of Doxorubicin Prodrug/Beta-Lapachone into Tumors

(2020) Qianyan Li et al.   International Journal of Nanomedicine

Despite Blocking Doxorubicin-Induced Vascular Damage, Quercetin Ameliorates Its Antibreast Cancer Activity

(2020) Hanan A. Henidi et al.   Oxidative Medicine and Cellular Longevity

Glycyrrhizin improved autophagy flux via HMGB1-dependent Akt/mTOR signaling pathway to prevent Doxorubicin-induced cardiotoxicity

(2020) Xueli Lv et al.   TOXICOLOGY

Curcumin induces chemosensitization to doxorubicin in Duke’s type B coloadenocarcinoma cell line

(2020) Jeyan Jayarajan et al.   MOLECULAR BIOLOGY REPORTS

Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1

(2020) Sarah Hassan et al.   PLoS One

Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters

(2020) Meenakshi Sudhakaran et al.   BIOCHEMICAL PHARMACOLOGY

Combining naringenin and metformin with doxorubicin enhances anticancer activity against triple-negative breast cancer in vitro and in vivo

(2020) Bharat Pateliya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway

(2020) Jung Joo Yoon et al.   MOLECULES

Resveratrol potentially increased the tumoricidal effect of doxorubicin on SKOV3 cancer stem cells in vitro

(2019) Ayda Pouyafar et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3γ

(2019) Xuanying Chen et al.   TOXICOLOGY MECHANISMS AND METHODS

Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats

(2019) Urmila Aswar et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

β-Lapachone protects against doxorubicin-induced nephrotoxicity via NAD+/AMPK/NF-kB in mice

(2019) Davoud Sanajou et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Enhanced antitumor efficacy and attenuated cardiotoxicity of doxorubicin in combination with lycopene liposomes

(2019) Jinfang Zhu et al.   JOURNAL OF LIPOSOME RESEARCH

Ginsenoside Rh2 Ameliorates Doxorubicin-Induced Senescence Bystander Effect in Breast Carcinoma Cell MDA-MB-231 and Normal Epithelial Cell MCF-10A

(2019) Jin-Gang Hou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genistein protects against doxorubicin-induced cardiotoxicity through Nrf-2/HO-1 signaling in mice model

(2019) Zhifeng Bai et al.   ENVIRONMENTAL TOXICOLOGY

Epigallocatechin-3-gallate inhibits doxorubicin-induced inflammation on human ovarian tissue

(2019) R Fabbri et al.   BIOSCIENCE REPORTS

Costunolide enhances sensitivity of K562/ADR chronic myeloid leukemia cells to doxorubicin through PI3K/Akt pathway

(2019) Hong Cai et al.   PHYTOTHERAPY RESEARCH

Ratiometric delivery of doxorubicin and berberine by liposome enables superior therapeutic index than Doxil®

(2019) Ruoshi Zhang et al.   Asian Journal of Pharmaceutical Sciences

Janus nanocarrier-based co-delivery of doxorubicin and berberine weakens chemotherapy-exacerbated hepatocellular carcinoma recurrence

(2019) Fan Zhang et al.   Acta Biomaterialia

Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity in rats

(2019) İ. Aktaş et al.   BIOTECHNIC & HISTOCHEMISTRY

Dihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies

(2019) Yutong Wang et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal

(2019) Shasha Song et al.   Frontiers in Pharmacology

β‐ LAP achone ameliorates doxorubicin‐induced cardiotoxicity via regulating autophagy and Nrf2 signalling pathways in mice

(2019) Saeed Nazari Soltan Ahmad et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Doxorubicin combined with betulinic acid or lonidamine in RGD ligand-targeted pH-sensitive micellar system for ovarian cancer treatment

(2019) Xin Jin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells

(2019) Ryohei Maruhashi et al.   Scientific Reports

Apolipoprotein E Deficiency Aggravates Neuronal Injury by Enhancing Neuroinflammation via the JNK/c-Jun Pathway in the Early Phase of Experimental Subarachnoid Hemorrhage in Mice

(2019) Yue Wu et al.   Oxidative Medicine and Cellular Longevity

Asiatic acid enhances intratumor delivery and the antitumor effect of pegylated liposomal doxorubicin by reducing tumor-stroma collagen

(2018) Luo Fang et al.   ACTA PHARMACOLOGICA SINICA

Anticancer Efficacy of the Combination of Berberine and PEGylated Liposomal Doxorubicin in Meth A Sarcoma-Bearing Mice

(2018) Jantana Yahuafai et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway

(2018) Subhadip Hajra et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy

(2018) Xin Li et al.   International Journal of Nanomedicine

Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells

(2018) Vidhya V. Iyer et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis

(2018) Xuejia Kang et al.   MOLECULAR PHARMACEUTICS

Protective Effect of Boswellic Acids against Doxorubicin-Induced Hepatotoxicity: Impact on Nrf2/HO-1 Defense Pathway

(2018) Bassant M. Barakat et al.   Oxidative Medicine and Cellular Longevity

Costunolide promotes the proliferation of human hair follicle dermal papilla cells and induces hair growth in C57BL/6 mice

(2018) Young Eun Kim et al.   Journal of Cosmetic Dermatology

Co-administration of genistein with doxorubicin-loaded polypeptide nanoparticles weakens the metastasis of malignant prostate cancer by amplifying oxidative damage

(2018) Guanyi Wang et al.   Biomaterials Science

Active Tumor-Targeted co-Delivery of Epigallocatechin Gallate and Doxorubicin in Nanoparticles for Combination Gastric Cancer Therapy

(2018) Fwu-Long Mi et al.   ACS Biomaterials-Science & Engineering

Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

(2018) Lisha Zhao et al.   Redox Biology

Active Tumor-Targeted co-Delivery of Epigallocatechin Gallate and Doxorubicin in Nanoparticles for Combination Gastric Cancer Therapy

(2018) Fwu-Long Mi et al.   ACS Biomaterials Science & Engineering

Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy

(2018) Jian Fang et al.   International Journal of Nanomedicine

Naringenin palliates cisplatin and doxorubicin gonadal toxicity in male rats

(2018) Amr A. Fouad et al.   TOXICOLOGY MECHANISMS AND METHODS

Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice

(2018) Zhi-Meng Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ferulic acid reverses P-glycoprotein-mediated multidrug resistance via inhibition of PI3K/Akt/NF-κB signaling pathway

(2018) Ganesan Muthusamy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Naringenin prevents doxorubicin-induced toxicity in kidney tissues by regulating the oxidative and inflammatory insult in Wistar rats

(2018) Tajdar Husain Khan et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

The epigallocatechin gallate derivative Y6 reverses drug resistance mediated by the ABCB1 transporter both in vitro and in vivo

(2018) Yan Wen et al.   Acta Pharmaceutica Sinica B

Glycyrrhetinic acid-conjugated polymeric prodrug micelles co-delivered with doxorubicin as combination therapy treatment for liver cancer

(2018) Tong Yang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Attenuation of doxorubicin-induced cardiotoxicity and genotoxicity by an indole-based natural compound 3,3′-diindolylmethane (DIM) through activation of Nrf2/ARE signaling pathways and inhibiting apoptosis

(2017) Subhadip Hajra et al.   FREE RADICAL RESEARCH

Cryptotanshinone potentiates the antitumor effects of doxorubicin on gastric cancer cells via inhibition of STAT3 activity

(2017) Jiye Wang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

(−)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice

(2017) Yu-Fei Yao et al.   LIFE SCIENCES

Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice

(2017) K. Petroni et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

(2017) Yimeng Zhang et al.   TOXICOLOGY

Costunolide enhances doxorubicin-induced apoptosis in prostate cancer cells via activated mitogen-activated protein kinases and generation of reactive oxygen species

(2017) Jiasheng Chen et al.   Oncotarget

Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

(2017) Chen Zhu et al.   Oncotarget

Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells

(2017) Yan Wen et al.   Oncotarget

Protein-Ligand Blind Docking Using QuickVina-W With Inter-Process Spatio-Temporal Integration

(2017) Nafisa M. Hassan et al.   Scientific Reports

Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways

(2017) Eman M. Mantawy et al.   Scientific Reports

Cardiotoxic and Dyslipidemic Effects of Doxorubicin and Betulinic Acid Amide

(2016) M. G. Klinnikova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways

(2016) Nehal M. Elsherbiny et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Reactive oxygen species responsive drug releasing nanoparticle based on chondroitin sulfate–anthocyanin nanocomplex for efficient tumor therapy

(2016) Dooyong Jeong et al.   JOURNAL OF CONTROLLED RELEASE

Amelioration of Doxorubicin-Induced Cardiac and Renal Toxicity by Oxycarotenoid Lutein and Its Mechanism of Action

(2016) Edakkadath Raghavan Sindhu et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Naringenin Ameliorates Doxorubicin Toxicity and Hypoxic Condition in Dalton's Lymphoma Ascites Tumor Mouse Model: Evidence from Electron Paramagnetic Resonance Imaging

(2016) Venkatesan Kathiresan et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats

(2016) Nasser Razmaraii et al.   LIFE SCIENCES

Baicalein alleviates doxorubicin-induced cardiotoxicity via suppression of myocardial oxidative stress and apoptosis in mice

(2016) Bidya Dhar Sahu et al.   LIFE SCIENCES

Protective effect of berberine on doxorubicin-induced acute hepatorenal toxicity in rats

(2016) XUEYAN CHEN et al.   Molecular Medicine Reports

Geniposide reverses multidrug resistance in vitro and in vivo by inhibiting the efflux function and expression of P-glycoprotein

(2016) Hefei Huang et al.   Experimental and Therapeutic Medicine

Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer

(2015) Ting Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study

(2015) Noha M. Saeed et al.   BIOCHEMICAL PHARMACOLOGY

Icariin Enhances Cytotoxicity of Doxorubicin in Human Multidrug-Resistant Osteosarcoma Cells by Inhibition of ABCB1 and Down-Regulation of the PI3K/Akt Pathway

(2015) Zhendong Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Luteolin Attenuates Doxorubicin-Induced Cytotoxicity to MCF-7 Human Breast Cancer Cells

(2015) Yasunori Sato et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Self-assembled betulinic acid protects doxorubicin induced apoptosis followed by reduction of ROS–TNF-α–caspase-3 activity

(2015) Sandeep Kumar Dash et al.   BIOMEDICINE & PHARMACOTHERAPY

Boswellic acids synergize antitumor activity and protect against the cardiotoxicity of doxorubicin in mice bearing Ehrlich’s carcinoma

(2015) Shimaa A. Ali et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

(2015) Khalid O Alfarouk et al.   Cancer Cell International

Co-delivery of baicalein and doxorubicin by hyaluronic acid decorated nanostructured lipid carriers for breast cancer therapy

(2015) Qian Liu et al.   DRUG DELIVERY

Principles of chemotherapy

(2015) Elisabeth Åvall Lundqvist et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Glycyrrhizin Conjugated Dendrimer and Multi-Walled Carbon Nanotubes for Liver Specific Delivery of Doxorubicin

(2015) Prashant K. Chopdey et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Protective effects of berberine against doxorubicin-induced cardiotoxicity in rats by inhibiting metabolism of doxorubicin

(2015) Gang Hao et al.   XENOBIOTICA

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

(2015) Dong-Gun Kim et al.   Oncotarget

Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression

(2014) Qinghua Dong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

(2014) Eman M. Mantawy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genotoxic and cytotoxic effects of doxorubicin and silymarin on human hepatocellular carcinoma cells

(2014) E Yurtcu et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Cardioprotective effect of ammonium glycyrrhizinate against doxorubicin-induced cardiomyopathy in experimental animals

(2014) Munish Garg et al.   INDIAN JOURNAL OF PHARMACOLOGY

Doxorubicin-Induced Oxidative Stress in Rats Is Efficiently Counteracted by Dietary Anthocyanin Differently Enriched Strawberry (Fragaria × ananassa Duch.)

(2014) Jacopo Diamanti et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective Role of Naringenin Against Doxorubicin-Induced Cardiotoxicity in a Rat Model: Histopathology and mRNA Expression Profile Studies

(2014) Swathika Subburaman et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Synergistic cytotoxic effect of genistein and doxorubicin on drug-resistant human breast cancer MCF-7/Adr cells

(2014) JIA-PENG XUE et al.   ONCOLOGY REPORTS

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway

(2013) Ai-Mei Gao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft

(2013) Anil Mittal et al.   PHYTOMEDICINE

Diindolilmethane (DIM) selectively inhibits cancer stem cells

(2012) Alexandre Semov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protective Effects of Berberine on Doxorubicin-Induced Hepatotoxicity in Mice

(2012) Xiaoyan Zhao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage

(2012) Timothy J. Wendorff et al.   JOURNAL OF MOLECULAR BIOLOGY

Preventive and protective effects of silymarin on doxorubicin-induced testicular damages correlate with changes in c-myc gene expression

(2012) H. Malekinejad et al.   PHYTOMEDICINE

Alleviation of doxorubicin-induced nephrotoxicity and hepatotoxicity by chrysin in Wistar rats

(2012) Summya Rashid et al.   TOXICOLOGY MECHANISMS AND METHODS

Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation

(2011) Wei-Tien Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Protective Effects of Silymarin against Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity in Rats

(2011) Aleksandar Rašković et al.   MOLECULES

Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: The role of glutathione

(2011) Heather M. Brechbuhl et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alleviation of doxorubicin-induced toxicities by anthocyanin-rich bilberry (Vaccinium myrtillus L.) extract in rats and mice

(2010) Eun Hye Choi et al.   BIOFACTORS

Cardioprotective effects of epigallocatechin-3-gallate against doxorubicin-induced cardiomyocyte injury

(2010) Jin Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver

(2010) Nirav Patel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin

(2009) Jing Zhou et al.   BIOCHEMICAL PHARMACOLOGY

Protective effects of β-carotene against the genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster

(2009) C.D. Dias et al.   GENETICS AND MOLECULAR RESEARCH

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE