β‐ LAP achone ameliorates doxorubicin‐induced cardiotoxicity via regulating autophagy and Nrf2 signalling pathways in mice

β-Lapachone protects against doxorubicin-induced nephrotoxicity via NAD+/AMPK/NF-kB in mice

(2019) Davoud Sanajou et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Micheliolide Protects Against Doxorubicin-Induced Cardiotoxicity in Mice by Regulating PI3K/Akt/NF-kB Signaling Pathway

(2019) Ashkan Kalantary-Charvadeh et al.   Cardiovascular Toxicology

AMPK: A promising molecular target for combating cisplatin toxicities

(2019) Nadereh Rashtchizadeh et al.   BIOCHEMICAL PHARMACOLOGY

Oxidative stress injury in doxorubicin-induced cardiotoxicity

(2019) Mei Songbo et al.   TOXICOLOGY LETTERS

Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

(2018) Pernille Tveden-Nyborg et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Neochlorogenic acid inhibits against LPS-activated inflammatory responses through up-regulation of Nrf2/HO-1 and involving AMPK pathway

(2018) Sun Young Park et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Dunnione protects against experimental cisplatin-induced nephrotoxicity by modulating NQO1 and NAD+ levels

(2018) Saeed Nazari Soltan Ahmad et al.   FREE RADICAL RESEARCH

Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products

(2018) Jie Yu et al.   PHYTOMEDICINE

Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?

(2018) Jenelle Govender et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

GW29-e0611 Acacetin inhibits doxorubicin–induced cardiotoxicity by activating Sirt1/AMPK/Nrf2 pathway

(2018) Weiyin Wu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling

(2017) Rabia Johnson et al.   MOLECULES

Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity

(2017) Donato Cappetta et al.   Oxidative Medicine and Cellular Longevity

Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway

(2017) Shudong Wang et al.   Cell Death & Disease

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

β-Lapachone increases phase II antioxidant enzyme expression via NQO1-AMPK/PI3K-Nrf2/ARE signaling in rat primary astrocytes

(2016) Jin-Sun Park et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity

(2016) Woo-Baek Chung et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

Efficacy and Cardiotoxicity of Liposomal Doxorubicin-Based Chemotherapy in Advanced Breast Cancer: A Meta-Analysis of Ten Randomized Controlled Trials

(2015) Meiyuan Xing et al.   PLoS One

β-Lapachone ameliorates murine cisplatin nephrotoxicity: NAD + , NQO1, and SIRT1 at the crossroads of metabolism, injury, and inflammation

(2014) Christopher Y. Lu   KIDNEY INTERNATIONAL

Augmentation of NAD+ by NQO1 attenuates cisplatin-mediated hearing impairment

(2014) H-J Kim et al.   Cell Death & Disease

The Cellular Autophagy Markers Beclin-1 and LC3B-II are Increased During Reperfusion in Fibrillated Mouse Hearts

(2013) Gregory Meyer et al.   CURRENT PHARMACEUTICAL DESIGN

Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1)

(2013) María Julia Lamberti et al.   PHYTOMEDICINE

Beta-Lapachone, a Modulator of NAD Metabolism, Prevents Health Declines in Aged Mice

(2012) Jeong-sook Lee et al.   PLoS One

Phase II, Open-Label, Randomized, Multicenter Study Comparing the Efficacy and Safety of Olaparib, a Poly (ADP-Ribose) Polymerase Inhibitor, and Pegylated Liposomal Doxorubicin in Patients WithBRCA1orBRCA2Mutations and Recurrent Ovarian Cancer

(2011) Stan B. Kaye et al.   JOURNAL OF CLINICAL ONCOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS