Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury

Regeneration of Functional Neurons After Spinal Cord Injury via in situ NeuroD1-Mediated Astrocyte-to-Neuron Conversion

(2021) Brendan Puls et al.   Frontiers in Cell and Developmental Biology

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

Neurog2 directly converts astrocytes into functional neurons in midbrain and spinal cord

(2021) Fei Liu et al.   Cell Death & Disease

EphB2 knockdown decreases the formation of astroglial‐fibrotic scars to promote nerve regeneration after spinal cord injury in rats

(2021) Jian Wu et al.   CNS Neuroscience & Therapeutics

Gene therapy for ALS: A review

(2021) Defne A. Amado et al.   MOLECULAR THERAPY

Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming

(2021) Álvaro Herrero-Navarro et al.   Science Advances

Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB

(2021) Roy Maimon et al.   NATURE NEUROSCIENCE

Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2

(2021) J. Kempf et al.   Cell Reports

Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1

(2021) Meiling Zhou et al.   Stem Cell Reports

Revisiting astrocyte to neuron conversion with lineage tracing in vivo

(2021) Lei-Lei Wang et al.   CELL

Improved tools to study astrocytes

(2020) Xinzhu Yu et al.   NATURE REVIEWS NEUROSCIENCE

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

(2020) Haibo Zhou et al.   CELL

Overexpression of the transcription factors OCT4 and KLF4 improves motor function after spinal cord injury

(2020) Xianpeng Huang et al.   CNS Neuroscience & Therapeutics

Review of Rodent Euthanasia Methods

(2020) Nirah H Shomer et al.   Journal of the American Association for Laboratory Animal Science

Dissecting the Dual Role of the Glial Scar and Scar-Forming Astrocytes in Spinal Cord Injury

(2020) Tuo Yang et al.   Frontiers in Cellular Neuroscience

Isolation, culture, and downstream characterization of primary microglia and astrocytes from adult rodent brain and spinal cord

(2020) Nilesh M. Agalave et al.   JOURNAL OF NEUROSCIENCE METHODS

Reversing a model of Parkinson’s disease with in situ converted nigral neurons

(2020) Hao Qian et al.   NATURE

Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis

(2020) Jean-Pierre Roussarie et al.   NEURON

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

Astrocytic reprogramming combined with rehabilitation strategy improves recovery from spinal cord injury

(2020) Tuo Yang et al.   FASEB JOURNAL

Reactive Astrogliosis: Implications in Spinal Cord Injury Progression and Therapy

(2020) Xinyu Li et al.   Oxidative Medicine and Cellular Longevity

The neuroanatomical–functional paradox in spinal cord injury

(2020) Karim Fouad et al.   Nature Reviews Neurology

Conditional ablation of reactive astrocytes to dissect their roles in spinal cord injury and repair

(2019) Yakun Gu et al.   BRAIN BEHAVIOR AND IMMUNITY

Antisense Oligonucleotide Therapies for Neurodegenerative Diseases

(2019) C. Frank Bennett et al.   Annual Review of Neuroscience

Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex

(2019) Nicola Mattugini et al.   NEURON

Dissecting spinal cord regeneration

(2018) Michael V. Sofroniew   NATURE

Required growth facilitators propel axon regeneration across complete spinal cord injury

(2018) Mark A. Anderson et al.   NATURE

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Cell biology of spinal cord injury and repair

(2017) Timothy M. O’Shea et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferating NG2-Cell-Dependent Angiogenesis and Scar Formation Alter Axon Growth and Functional Recovery After Spinal Cord Injury in Mice

(2017) Zoe C. Hesp et al.   JOURNAL OF NEUROSCIENCE

Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

(2017) Andrew P. Tosolini et al.   Frontiers in Molecular Neuroscience

RNAi mechanisms in Huntington’s disease therapy: siRNA versus shRNA

(2017) Sebastian Aguiar et al.   Translational Neurodegeneration

STIMs and Orai1 regulate cytokine production in spinal astrocytes

(2016) Xinghua Gao et al.   Journal of Neuroinflammation

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Gene therapy returns to centre stage

(2015) Luigi Naldini   NATURE

Abrogation of  -Catenin Signaling in Oligodendrocyte Precursor Cells Reduces Glial Scarring and Promotes Axon Regeneration after CNS Injury

(2014) J. P. Rodriguez et al.   JOURNAL OF NEUROSCIENCE

In vivo conversion of astrocytes to neurons in the injured adult spinal cord

(2014) Zhida Su et al.   Nature Communications

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

(2012) Holly B. Kordasiewicz et al.   NEURON

Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons

(2010) Matthew RJ Mason et al.   MOLECULAR THERAPY

siRNA vs. shRNA: Similarities and differences

(2009) Donald D. Rao et al.   ADVANCED DRUG DELIVERY REVIEWS

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

(2009) Yuanchao Xue et al.   MOLECULAR CELL