Astaxanthin attenuates ferroptosis via Keap1-Nrf2/HO-1 signaling pathways in LPS-induced acute lung injury

Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2 ′ -Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester

(2022) Deng Guan et al.   Oxidative Medicine and Cellular Longevity

Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury

(2022) Fangyi Gong et al.   Aging-US

Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis

(2022) Xing Li et al.   COMPUTERS IN BIOLOGY AND MEDICINE

High Level of Uric Acid Promotes Atherosclerosis by Targeting NRF2-Mediated Autophagy Dysfunction and Ferroptosis

(2022) Wei Yu et al.   Oxidative Medicine and Cellular Longevity

Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2/HO-1 pathway

(2021) Jiucui Li et al.   Journal of Translational Medicine

Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1

(2021) Na Kong et al.   Acta Pharmaceutica Sinica B

The Role of Ferroptosis in Acute Respiratory Distress Syndrome

(2021) Mengdi Qu et al.   Frontiers in Medicine

Sevoflurane inhibits ferroptosis: A new mechanism to explain its protective role against lipopolysaccharide-induced acute lung injury

(2021) Xiao Liu et al.   LIFE SCIENCES

Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

(2021) Shuangqiu Wang et al.   Drug Design Development and Therapy

Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction

(2021) Zheng Xiao et al.   Bioengineered

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis

(2020) Pengfei Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Respiratory drive in the acute respiratory distress syndrome: pathophysiology, monitoring, and therapeutic interventions

(2020) Elena Spinelli et al.   INTENSIVE CARE MEDICINE

Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease

(2020) Nao Yan et al.   Frontiers in Neuroscience

Ferroptosis is involved in alcohol-induced cell death in vivo and in vitro

(2020) Chun-Yu Liu et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Astaxanthin anticancer effects are mediated through multiple molecular mechanisms: A systematic review

(2020) Immacolata Faraone et al.   PHARMACOLOGICAL RESEARCH

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer

(2020) Arnaud Blomme et al.   Nature Communications

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

(2020) Hui Dong et al.   Aging-US

The emerging role of ferroptosis in inflammation

(2020) Yitian Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Ferroptosis and kidney disease

(2020) Diego Martin-Sanchez et al.   NEFROLOGIA

Ferroptosis and its potential role in the physiopathology of Parkinson’s Disease

(2020) Laura Mahoney-Sánchez et al.   PROGRESS IN NEUROBIOLOGY

Cross Talk Between Ferroptosis and Cerebral Ischemia

(2020) Xu She et al.   Frontiers in Neuroscience

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Potential Molecular Mechanisms of Plantain in the Treatment of Gout and Hyperuricemia Based on Network Pharmacology

(2020) Pei Liu et al.   Evidence-based Complementary and Alternative Medicine

Comparative Toxicogenomics Database (CTD): update 2021

(2020) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Ferroptosis, a new form of cell death: opportunities and challenges in cancer

(2019) Yanhua Mou et al.   Journal of Hematology & Oncology

Identification of PRDX6 as a regulator of ferroptosis

(2019) Bin Lu et al.   ACTA PHARMACOLOGICA SINICA

Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

(2019) Xiaoqing Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Heme oxygenase-1 mediates BAY 11–7085 induced ferroptosis

(2018) Ling-Chu Chang et al.   CANCER LETTERS

Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review

(2018) Sergio Davinelli et al.   Nutrients

Ferroptosis and necroinflammation, a yet poorly explored link

(2018) Bettina Proneth et al.   CELL DEATH AND DIFFERENTIATION

Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners

(2018) Callie Farruggia et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Astaxanthin: A mechanistic review on its biological activities and health benefits

(2018) Sajad Fakhri et al.   PHARMACOLOGICAL RESEARCH

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

(2018) Chuanhong Wu et al.   Scientific Reports

Ferroptosis and Its Role in Diverse Brain Diseases

(2018) Abigail Weiland et al.   MOLECULAR NEUROBIOLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Iron and ferroptosis: A still ill-defined liaison

(2017) Sebastian Doll et al.   IUBMB LIFE

The α6β4 integrin promotes resistance to ferroptosis

(2017) Caitlin W. Brown et al.   JOURNAL OF CELL BIOLOGY

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database

(2017) Xia Wang et al.   NUCLEIC ACIDS RESEARCH

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

(2017) Ioannis Poursaitidis et al.   Cell Reports

The Roles of NRF2 in Modulating Cellular Iron Homeostasis

(2017) Michael John Kerins et al.   ANTIOXIDANTS & REDOX SIGNALING

Acute Lung Injury: A Clinical and Molecular Review

(2016) Yasmeen Butt et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Getting the most out of PubChem for virtual screening

(2016) Sunghwan Kim   Expert Opinion on Drug Discovery

Potential Anti-Atherosclerotic Properties of Astaxanthin

(2016) Yoshimi Kishimoto et al.   Marine Drugs

Structural basis of Keap1 interactions with Nrf2

(2015) Peter Canning et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

(2015) Min-Young Kwon et al.   Oncotarget

Acyl-CoA Metabolism and Partitioning

(2014) Trisha J. Grevengoed et al.   Annual Review of Nutrition

Monitoring Keap1–Nrf2 interactions in single live cells

(2014) Liam Baird et al.   BIOTECHNOLOGY ADVANCES

cytoHubba: identifying hub objects and sub-networks from complex interactome

(2014) Chia-Hao Chin et al.   BMC Systems Biology

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SwissTargetPrediction: a web server for target prediction of bioactive small molecules

(2014) David Gfeller et al.   NUCLEIC ACIDS RESEARCH

OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders

(2014) Joanna S. Amberger et al.   NUCLEIC ACIDS RESEARCH

Resolution of Acute Inflammation in the Lung

(2013) Bruce D. Levy et al.   Annual Review of Physiology

Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

(2013) L. Baird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview

(2010) Ken Itoh et al.   ANTIOXIDANTS & REDOX SIGNALING

Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks

(2010) Jing Gao et al.   BIOINFORMATICS

GeneCards Version 3: the human gene integrator

(2010) M. Safran et al.   Database-The Journal of Biological Databases and Curation

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluid balance and colloid osmotic pressure in acute respiratory failure: optimizing therapy

(2009) Sushma K Cribbs et al.   Expert Review of Respiratory Medicine

The xc− cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

(2008) M Lo et al.   BRITISH JOURNAL OF CANCER