2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-05-19
DOI
10.1038/s41467-020-16126-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aspirin-triggered proresolving mediators stimulate resolution in cancer
- (2019) Molly M. Gilligan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
- (2019) Kim Vriens et al. NATURE
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
- (2018) Rachana Patel et al. EMBO Molecular Medicine
- From the unfolded protein response to metabolic diseases – lipids under the spotlight
- (2018) Nurulain Ho et al. JOURNAL OF CELL SCIENCE
- Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer
- (2018) Maha Hussain et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer
- (2018) Matthew R. Smith et al. NEW ENGLAND JOURNAL OF MEDICINE
- LipiDex: An Integrated Software Package for High-Confidence Lipid Identification
- (2018) Paul D. Hutchins et al. Cell Systems
- Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors
- (2017) Doriane Lorendeau et al. METABOLIC ENGINEERING
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
- (2017) Matthew J. Hangauer et al. NATURE
- Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library
- (2017) Hiroshi Tsugawa et al. Journal of Cheminformatics
- Lipid degradation promotes prostate cancer cell survival
- (2017) Harri M. Itkonen et al. Oncotarget
- Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade
- (2017) Thomas W. Flaig et al. Oncotarget
- Metabolic Vulnerabilities of Prostate Cancer: Diagnostic and Therapeutic Opportunities
- (2017) Giorgia Zadra et al. Cold Spring Harbor Perspectives in Medicine
- Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer
- (2017) Jianneng Li et al. eLife
- c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks
- (2017) Stefan J. Barfeld et al. EBioMedicine
- The Metabolic Phenotype of Prostate Cancer
- (2017) Eric Eidelman et al. Frontiers in Oncology
- Enzalutamide Versus Bicalutamide in Castration-Resistant Prostate Cancer: The STRIVE Trial
- (2016) David F. Penson et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy and safety of enzalutamide versus bicalutamide for patients with metastatic prostate cancer (TERRAIN): a randomised, double-blind, phase 2 study
- (2016) Neal D Shore et al. LANCET ONCOLOGY
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- The Perseus computational platform for comprehensive analysis of (prote)omics data
- (2016) Stefka Tyanova et al. NATURE METHODS
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism
- (2016) Supriya Shah et al. Oncotarget
- Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide
- (2016) Julia Hoefer et al. Oncotarget
- Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer
- (2016) Steven Kregel et al. Oncotarget
- Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis
- (2016) Stefan Christen et al. Cell Reports
- Proteomic Upregulation of Fatty Acid Synthase and Fatty Acid Binding Protein 5 and Identification of Cancer- and Race-Specific Pathway Associations in Human Prostate Cancer Tissues
- (2016) Jennifer S. Myers et al. Journal of Cancer
- Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53- deficiency-driven castration-resistant prostate cancer
- (2016) Lei Wang et al. EBioMedicine
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer
- (2015) Fabiola Bovenga et al. Cell Metabolism
- Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells
- (2014) Yuanyuan Cui et al. ENDOCRINE-RELATED CANCER
- Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
- (2014) Jürgen Cox et al. MOLECULAR & CELLULAR PROTEOMICS
- Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer
- (2014) I. R. Schlaepfer et al. MOLECULAR CANCER THERAPEUTICS
- Enzalutamide in Metastatic Prostate Cancer before Chemotherapy
- (2014) Tomasz M. Beer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model
- (2014) H G Nguyen et al. ONCOGENE
- Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
- (2013) Vivek K. Arora et al. CELL
- LipidBlast in silico tandem mass spectrometry database for lipid identification
- (2013) Tobias Kind et al. NATURE METHODS
- Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains
- (2013) R. Volmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An F876L Mutation in Androgen Receptor Confers Genetic and Phenotypic Resistance to MDV3100 (Enzalutamide)
- (2013) M. Korpal et al. Cancer Discovery
- A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509
- (2013) J. D. Joseph et al. Cancer Discovery
- Overcoming mutation-based resistance to antiandrogens with rational drug design
- (2013) Minna D Balbas et al. eLife
- The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man
- (2012) Naomi L. Sharma et al. CANCER CELL
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
- (2011) Charles E Massie et al. EMBO JOURNAL
- Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
- (2011) K. Zaugg et al. GENES & DEVELOPMENT
- Animal Research: Reporting in vivo Experiments—The ARRIVE Guidelines
- (2011) Carol Kilkenny et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
- (2011) Jürgen Cox et al. JOURNAL OF PROTEOME RESEARCH
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer
- (2009) Amjad P. Khan et al. MOLECULAR & CELLULAR PROTEOMICS
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- The Universal Protein Resource (UniProt) in 2010
- (2009) NUCLEIC ACIDS RESEARCH
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
- Mitochondrial 2,4-dienoyl-CoA Reductase Deficiency in Mice Results in Severe Hypoglycemia with Stress Intolerance and Unimpaired Ketogenesis
- (2009) Ilkka J. Miinalainen et al. PLoS Genetics
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now