Design and Organocatalytic Asymmetric Synthesis of Indolyl-Pyrroloindoles Bearing Both Axial and Central Chirality

Organocatalytic Atroposelective Synthesis of N−N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation

(2022) Ke‐Wei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Axially Chiral C–N Atropisomers

(2022) Patricia Rodríguez-Salamanca et al.   CHEMISTRY-A EUROPEAN JOURNAL

Atroposelective Desymmetrization of Resorcinol-Bearing Quinazolinones via Cu-Catalyzed C–O Bond Formation

(2022) Hyung Yoon et al.   ORGANIC LETTERS

Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls

(2022) Hui Yang et al.   Nature Communications

Chiral phosphoric acid-catalyzed regio- and enantioselective reactions of functionalized propargylic alcohols

(2022) Chenxiao Qian et al.   Organic Chemistry Frontiers

Transition Metal-Catalyzed Biaryl Atropisomer Synthesis via a Torsional Strain Promoted Ring-Opening Reaction

(2022) Xue Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Asymmetric Synthesis of Axially Chiral 3,3'‐Bisindoles by Direct Coupling of Indole Rings

(2022) Feng‐Tao Sheng et al.   CHINESE JOURNAL OF CHEMISTRY

Chiral Brønsted Acid Catalyzed Enantioselective Synthesis of Spiro-Isoindolinone-Indolines via Formal [3 + 2] Cycloaddition

(2022) Rajshekhar A. Unhale et al.   ORGANIC LETTERS

SCpRh(III)-Catalyzed Enantioselective Synthesis of Atropisomers by C2-Arylation of Indoles with 1-Diazonaphthoquinones

(2022) Si-Yong Yin et al.   ORGANIC LETTERS

Atropisomers beyond the C–C axial chirality: Advances in catalytic asymmetric synthesis

(2022) Guang-Jian Mei et al.   Chem

Organocatalytic Enantioselective 1,10-Addition of Alkynyl Indole Imine Methides with Thiazolones: An Access to Axially Chiral Tetrasubstituted Allenes

(2022) Xiao Lin et al.   ORGANIC LETTERS

Atropisomers with Axial and Point Chirality: Synthesis and Applications

(2022) Xing-Feng Bai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalytic Atroposelective Synthesis of Indole Derivatives Bearing Axial Chirality: Strategies and Applications

(2022) Hong-Hao Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalyst-Controlled Divergent Reactions of 2,3-Disubstituted Indoles with Propargylic Alcohols: Synthesis of 3H-Benzo[b]azepines and Axially Chiral Tetrasubstituted Allenes

(2022) Chenxiao Qian et al.   ORGANIC LETTERS

Catalytic and Enantioselective Control of the C−N Stereogenic Axis via the Pictet‐Spengler Reaction

(2021) Ahreum Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N‐Heterocyclic Carbene‐Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C‐N Axial Chirality

(2021) Tingting Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium‐Catalyzed C‐H Activation‐Based Construction of  Axiall and Centrally Chiral Indenes through Two Discrete Insertions

(2021) Xingwei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxygen‐linked Cyclopentadienyl Rh(III) Complexes‐Catalyzed Asymmetric C−H Arylation of Benzo[h]quinolines with 1‐Diazonaphthoquinones

(2021) Chong-Qing Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Highly Atroposelective Rhodium(II)-Catalyzed N–H Bond Insertion: Access to Axially Chiral N-Arylindolocarbazoles

(2021) Qiao Ren et al.   ACS Catalysis

Enantioselective Synthesis of Atropisomeric Biaryls by Pd‐Catalyzed Asymmetric Buchwald–Hartwig Amination

(2021) Peng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Atroposelective Construction of Pentatomic Heterobiaryl Scaffolds

(2021) Xiao‐Long He et al.   ChemCatChem

Synthesis of Atropisomers by Transition-Metal-Catalyzed Asymmetric C–H Functionalization Reactions

(2021) Chen-Xu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Nitrogen–Nitrogen Biaryl Atropisomers via Copper-Catalyzed Friedel–Crafts Alkylation Reaction

(2021) Xiao-Mei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalyst-controlled site-selective arene C–H functionalization

(2021) Jian-Hui Mao et al.   Nature Chemistry

Construction of Atropisomeric 3-Arylindoles via Enantioselective Cacchi Reaction

(2021) Xiaojiao Li et al.   ORGANIC LETTERS

Asymmetric Synthesis of Axially Chiral Naphthyl-C3-indoles via a Palladium-Catalyzed Cacchi Reaction

(2021) Cong-Shuai Wang et al.   ORGANIC LETTERS

Enantioselective and Diastereoselective C–H Alkylation of Benzamides: Synergized Axial and Central Chirality via a Single Stereodetermining Step

(2021) Jinlei Wang et al.   ACS Catalysis

Rational design and atroposelective synthesis of N–N axially chiral compounds

(2021) Guang-Jian Mei et al.   Chem

Diversity-Oriented Enantioselective Construction of Atropisomeric Heterobiaryls and N -Aryl Indoles via Vinylidene Ortho -Quinone Methides

(2021) Da Xu et al.   CCS Chemistry

Rhodium‐Catalyzed Atroposelective Access to Axially Chiral Olefins via C−H Bond Activation and Directing Group Migration

(2021) Ruijie Mi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral-Phosphoric-Acid-Catalyzed Atroposelective C-H Amination of Arenes

(2020) Bin Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Synthesis of 3,3’‐Bisindoles Bearing Axial and Central Chirality: Using Isatin‐Derived Imines as Electrophiles

(2020) Feng‐Tao Sheng et al.   CHINESE JOURNAL OF CHEMISTRY

Catalytic Atroposelective Synthesis of N-Aryl Quinoid Compounds

(2020) Sagar D. Vaidya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Enantioselective Synthesis of Atropisomeric Aryl‐ p ‐Quinones: Platform Molecules for Diversity‐Oriented Synthesis of Biaryldiols

(2020) Ye‐Hui Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)‐Catalyzed Atroposelective Synthesis of Biaryls by C−H Activation and Intermolecular Coupling with Sterically Hindered Alkynes

(2020) Fen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of N–C Axially Chiral Compounds by Cu‐Catalyzed Atroposelective Aryl Amination

(2020) Johanna Frey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Synthesis of Chiral Allenes: Remote Asymmetric 1,8‐Addition of Indole Imine Methides

(2020) Xingguang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of 3,3′-Bisindoles Bearing Single Axial Chirality

(2020) Ke-Wei Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Atroposelective Synthesis of Axially Chiral 3-Arylindoles by Copper-Catalyzed Asymmetric Cross-Coupling of Indoles with Quinones and Naphthoquinones

(2020) Chao-Chao Xi et al.   ORGANIC LETTERS

DFT-Guided Phosphoric-Acid-Catalyzed Atroposelective Arene Functionalization of Nitrosonaphthalene

(2020) Wei-Yi Ding et al.   Chem

Chiral Spirocyclic Phosphoric Acids and Their Growing Applications

(2020) Xufeng Lin et al.   CHINESE JOURNAL OF CHEMISTRY

Chiral Naphthyl-C2-Indole as Scaffold for Phosphine Organocatalysis: Application in Asymmetric Formal [4 + 2] Cycloaddition Reactions

(2020) Tingting He et al.   ORGANIC LETTERS

Rhodium‐Catalyzed Atroposelective Construction of Indoles via C‐H Bond Activation

(2020) Lincong Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atropselective Dibrominations of a 1,1’-Disubstituted 2,2’-Biindolyl With Diverging Point-to-Axial Asymmetric Inductions. Deriving Diphosphane Ligands for Asymmetric Catalysis

(2019) Reinhard Brückner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters

(2019) Pei Zhang et al.   ORGANIC LETTERS

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Disparate Catalytic Scaffolds for Atroposelective Cyclodehydration

(2019) Yongseok Kwon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

(2019) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Barton–Zard Reaction To Access 3-Pyrrole-Containing Axially Chiral Skeletons

(2019) Xiao-Long He et al.   ACS Catalysis

Catalytic Enantioselective Pinacol and Meinwald Rearrangements for the Construction of Quaternary Stereocenters

(2019) Hua Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of N–C Axial Chirality through Atroposelective C–H Olefination of N-Arylindoles by Palladium/Amino Acid Cooperative Catalysis

(2019) Jitan Zhang et al.   ORGANIC LETTERS

Atroposelective Construction of Arylindoles by Chiral Phosphoric Acid-Catalyzed Cross-Coupling of Indoles and Quinones

(2019) Dong-Liang Lu et al.   ORGANIC LETTERS

Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination

(2019) He-Yuan Bai et al.   Nature Communications

Central‐to‐Axial Chirality Conversion Approach Designed on Organocatalytic Enantioselective Povarov Cycloadditions: First Access to Configurationally Stable Indole‐Quinoline Atropisomers

(2019) Vasco Corti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Atroposelective Phosphoric Acid Catalyzed Three-Component Cascade Reaction: Enantioselective Synthesis of Axially Chiral N-Arylindoles

(2019) Lei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

(2019) Fei Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic atroposelective construction of axially chiral arylquinones

(2019) Shuai Zhu et al.   Nature Communications

Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach

(2019) Yu-Chen Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles

(2019) Yu-Ping He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Phosphoric Acid Creates Promising Opportunities for Enantioselective Photoredox Catalysis

(2019) Shaoyu Li et al.   CHINESE JOURNAL OF CHEMISTRY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Divergent Control of Point and Axial Stereogenicity: Catalytic Enantioselective C−N Bond-Forming Cross-Coupling and Catalyst-Controlled Atroposelective Cyclodehydration

(2018) Yongseok Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls

(2018) Yidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bird's Eye View of Atropisomers Featuring a Five-Membered Ring

(2018) Damien Bonne et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Parameterization and Analysis of Peptide-Based Catalysts for the Atroposelective Bromination of 3-Arylquinazolin-4(3H)-ones

(2018) Jennifer M. Crawford et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

(2018) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substrate-Controlled Regioselective Arylations of 2-Indolylmethanols with Indoles: Synthesis of Bis(indolyl)methane and 3,3′-Bisindole Derivatives

(2017) Ying-Ying He et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

(2017) Vivek S. Raut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal–Knorr Reaction

(2017) Lei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

(2017) Yong-Bin Wang et al.   Nature Communications

Organocatalytic synthesis of chiral tetrasubstituted allenes from racemic propargylic alcohols

(2017) Deyun Qian et al.   Nature Communications

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts

(2016) Samantha Staniland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

(2016) Ji-Wei Zhang et al.   Nature Communications

Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

(2015) Ophélie Quinonero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Molecular Machines

(2015) Sundus Erbas-Cakmak et al.   CHEMICAL REVIEWS

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination

(2015) Matthew E. Diener et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

N-N-Coupled Indolo-sesquiterpene Atropo-Diastereomers from a Marine-Derived Actinomycete

(2012) Qingbo Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS