Atropisomers with Axial and Point Chirality: Synthesis and Applications

Atropisomers beyond the C–C axial chirality: Advances in catalytic asymmetric synthesis

(2022) Guang-Jian Mei et al.   Chem

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N–C Axially Chiral Compounds and Their Synthetic Applications

(2021) Osamu Kitagawa   ACCOUNTS OF CHEMICAL RESEARCH

Combined Dynamic Kinetic Resolution and C‐H Functionalization for Facile Synthesis of Non‐Biaryl‐Atropisomer‐type Axially Chiral Organosilanes

(2021) Li-Wen Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd-Catalyzed Enantioselective Tandem C–C Bond Activation/Cacchi Reaction between Cyclobutanones and o-Ethynylanilines

(2021) Wan-Chun Yang et al.   ORGANIC LETTERS

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Recent Advances in Catalytic Atroposelective Construction of Pentatomic Heterobiaryl Scaffolds

(2021) Xiao‐Long He et al.   ChemCatChem

Application of aromatic amide‐derived atropisomers as chiral solvating agents for discrimination of optically active mandelic acid derivatives in 1 H nuclear magnetic resonance spectroscopy

(2021) Xiaojing Zheng et al.   MAGNETIC RESONANCE IN CHEMISTRY

Advances in the Catalytic Asymmetric Synthesis of Atropisomeric Hexatomic N‐Heterobiaryls

(2020) Dao-Juan Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides

(2020) Xing-Wei Gu et al.   Nature Communications

Catalytic Asymmetric trans-Selective Hydrosilylation of Bisalkynes to Access AIE and CPL-Active Silicon-Stereogenic Benzosiloles

(2020) Ren-He Tang et al.   iScience

Enantioselective Cross-Exchange between C−I and C−C σ-Bonds

(2019) Yu-Li Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Catalytic Enantioselective Synthesis of Highly Functionalized Pentafluorosulfanylated Pyrrolidines

(2018) Qun Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ligand-Controlled Inversion of Diastereo- and Enantioselectivity in Silver-Catalyzed Azomethine Ylide–Imine Cycloaddition of Glycine Aldimino Esters with Imines

(2018) Bo Yu et al.   ORGANIC LETTERS

Carbonyl catalysis enables a biomimetic asymmetric Mannich reaction

(2018) Jianfeng Chen et al.   SCIENCE

Enantioselective synthesis of axially chiral vinyl arenes through palladium-catalyzed C–H olefination

(2018) Qiao-Ying Sun et al.   CHEMICAL COMMUNICATIONS

Pd-Catalyzed Enantioselective Ring Opening/Cross-Coupling and Cyclopropanation of Cyclobutanones

(2018) Jian Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Temperature-Controlled Bidirectional Enantioselectivity in Asymmetric Hydrogenation Reactions Utilizing Stereodynamic Iridium Complexes

(2017) Oliver Trapp et al.   SYNTHESIS-STUTTGART

Enantioselective synthesis of chiral acylsilanes by copper/HZNU-Phos-catalyzed asymmetric conjugate addition of diethyzinc to α,β-unsaturated acylsilanes

(2017) Ji-Yuan Lv et al.   RSC Advances

Tale of Twisted Molecules. Atropselective Photoreactions: Taming Light Induced Asymmetric Transformations through Non-biaryl Atropisomers

(2016) Elango Kumarasamy et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Michael Addition of Aldimino Esters with Chalcones Catalyzed by Silver/Xing-Phos: Mechanism-Oriented Divergent Synthesis of Chiral Pyrrolines

(2016) Xing-Feng Bai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability

(2016) Leena Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

A chemically powered unidirectional rotary molecular motor based on a palladium redox cycle

(2016) Beatrice S. L. Collins et al.   Nature Chemistry

N-tert-Butanesulfinyl imine and aromatic tertiary amide derived non-biaryl atropisomers as chiral ligands for silver-catalyzed endo-selective [3+2] cycloaddition of azomethine ylides with maleimides

(2016) Xing-Feng Bai et al.   TETRAHEDRON

Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds

(2016) Juan F. Collados et al.   ACS Catalysis

Tao-Phos-controlled desymmetrization of succinimide-based bisalkynes via asymmetric copper-catalyzed Huisgen alkyne–azide click cycloaddition: substrate scope and mechanism

(2016) Mu-Yi Chen et al.   RSC Advances

Temperature-Controlled Bidirectional Enantioselectivity in a Dynamic Catalyst for Asymmetric Hydrogenation

(2015) Golo Storch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic Amide-Derived Non-Biaryl Atropisomers as Highly Efficient Ligands in Silver-Catalyzed Asymmetric Cycloaddition Reactions

(2015) Xing-Feng Bai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Aromatic-Amide-Derived Nonbiaryl Atropisomer as Highly Efficient Ligand for Asymmetric Silver-Catalyzed [3 + 2] Cycloaddition

(2015) Xing-Feng Bai et al.   ACS Catalysis

Enantioselective conjugate addition of cyanide to chalcones catalyzed by a magnesium-Py-BINMOL complex

(2015) Cheng Dong et al.   Catalysis Science & Technology

Modular construction of multifunctional ligands for the enantioselective ruthenium-catalyzed carbenoid N–H insertion reaction: an enzyme-like and substrate-sensitive catalyst system

(2015) Wei-Sheng Huang et al.   RSC Advances

Enantioselective cyanosilylation of aldehydes catalyzed by a multistereogenic salen–Mn(iii) complex with a rotatable benzylic group as a helping hand

(2015) Yun-Long Wei et al.   RSC Advances

Enantioselective Fluorination of β-Ketoamides Catalyzed by Ar-BINMOL-derived SalanCopper Complex

(2014) Long-Sheng Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Modular Synthesis of Ar-BINMOL-Phos for Catalytic Asymmetric Alkynylation of Aromatic Aldehydes with Unexpected Reversal of Enantioselectivity

(2014) Tao Song et al.   ADVANCED SYNTHESIS & CATALYSIS

Multistereogenic Phosphine Ligand-promoted Palladium-Catalyzed Allylic Alkylation of Cyanoesters

(2014) Wen-Hui Deng et al.   ChemCatChem

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Enantioselective Copper-Catalyzed Azide-Alkyne Click Cycloaddition to Desymmetrization of Maleimide-Based Bis(alkynes)

(2014) Tao Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

Silicon-Based Bulky Group-Induced Remote Control and Conformational Preference in the Synthesis and Application of Isolable Atropisomeric Amides with Secondary Alcohol or Amine Moieties

(2014) Xing-Feng Bai et al.   Chemistry-An Asian Journal

Probing the evolution of an Ar-BINMOL-derived salen–Co(iii) complex for asymmetric Henry reactions of aromatic aldehydes: salan–Cu(ii) versus salen–Co(iii) catalysis

(2014) Yun-Long Wei et al.   RSC Advances

Modulation of Multifunctional N,O,P Ligands for Enantioselective Copper-Catalyzed Conjugate Addition of Diethylzinc and Trapping of the Zinc Enolate

(2013) Fei Ye et al.   Chemistry-An Asian Journal

New silver(I)–monophosphine complex derived from chiral Ar-BINMOL: synthesis and catalytic activity in asymmetric vinylogous Mannich reaction

(2013) Long-Sheng Zheng et al.   TETRAHEDRON

Chiral Ar-BINMOL-derived salan as fluorescent sensor for recognition of CuCl and cascade discrimination of α-amino acids

(2013) Fei Li et al.   TETRAHEDRON LETTERS

Asymmetric catalysis based on tropos ligands

(2012) Kohsuke Aikawa et al.   CHEMICAL COMMUNICATIONS

Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles

(2012) Zhan-Jiang Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Aromatic-Amide-Derived Olefins as a Springboard: Isomerization-Initiated Palladium-Catalyzed Hydrogenation of Olefins and Reductive Decarbonylation of Acyl Chlorides with Hydrosilane

(2012) Xing-Feng Bai et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Chiral Cu-Salan Catalyst with a Rotatable Aromatic π-Wall: Molecular Recognition-Oriented Asymmetric Henry Transformation of Aromatic Aldehydes

(2012) Fei Li et al.   Chemistry-An Asian Journal

Synthesis of Ar-BINMOL Ligands by [1,2]-Wittig Rearrangement to Probe Their Catalytic Activity in 1,2-Addition Reactions of Aldehydes with Grignard Reagents

(2012) Long-Sheng Zheng et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Lewis acid-promoted reduction of acylsilanes to α-hydroxysilanes by diethylzinc

(2012) Guang Gao et al.   TETRAHEDRON LETTERS

Neighboring Lithium-Assisted [1,2]-Wittig Rearrangement: Practical Access to Diarylmethanol-Based 1,4-Diols and Optically Active BINOL Derivatives with Axial and sp3-Central Chirality

(2011) Guang Gao  et al.   CHEMISTRY-A EUROPEAN JOURNAL

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Ar-BINMOLs with Axial and sp3 Central Chirality - Characterization, Chiroptical Properties, and Application in Asymmetric Catalysis

(2011) Guang Gao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Substituted Functional Olefins Through Lateral Sequential Lithiation/Silylation/Condensation of Tertiary Aromatic Amides: A Ligand for Phosphane-Free Palladium-Catalyzed Suzuki Coupling Reactions

(2011) Li-Wen Xu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantiomerically pure bicyclo[3.3.1]nona-2,6-diene as the sole source of enantioselectivity in BIPHEP-Rh asymmetric hydrogenation

(2008) Tharmalingam Punniyamurthy et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Enantioselective Michael Addition of 2,4-Pentandione to Nitroalkenes Promoted by Bifunctional Thioureas with Central and Axial Chiral Elements

(2008) Fang-Zhi Peng et al.   JOURNAL OF ORGANIC CHEMISTRY