Atroposelective Desymmetrization of Resorcinol-Bearing Quinazolinones via Cu-Catalyzed C–O Bond Formation

Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones

(2021) Fan Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Site-Selective Cross-Coupling of Polyhalogenated Arenes and Heteroarenes with Identical Halogen Groups

(2021) Vignesh Palani et al.   CHEMICAL REVIEWS

Late-Stage Diversification: A Motivating Force in Organic Synthesis

(2021) Kelly E. Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chirality-matched catalyst-controlled macrocyclization reactions

(2021) Jaeyeon Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enantioselective Synthesis of N–C Axially Chiral Compounds by Cu‐Catalyzed Atroposelective Aryl Amination

(2020) Johanna Frey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late-stage oxidative C(sp3)–H methylation

(2020) Kaibo Feng et al.   NATURE

Late-Stage Diversification of Natural Products

(2020) Benke Hong et al.   ACS Central Science

Late-Stage Functionalization

(2020) Jonas Börgel et al.   Chem

Catalytic Dynamic Kinetic Resolutions in Tandem to Construct Two-Axis Terphenyl Atropisomers

(2020) Omar M. Beleh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-selective C-H hydroxylation of pentacyclic triterpenoids directed by transient chiral pyridine-imino groups

(2020) Tong Mu et al.   Nature Communications

Oxalohydrazide Ligands for Copper‐Catalyzed C−O Coupling Reactions with High Turnover Numbers

(2020) Ritwika Ray et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Atropisomeric Anilides Synthesis via Cu-Catalyzed Intramolecular Adjacent C–N Coupling

(2019) Xiaozhong Fan et al.   ACS Catalysis

Oxalic Diamides and tert-Butoxide: Two Types of Ligands Enabling Practical Access to Alkyl Aryl Ethers via Cu-Catalyzed Coupling Reaction

(2019) Zhixiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry

(2019) Seb Caille et al.   JOURNAL OF ORGANIC CHEMISTRY

Divergent Control of Point and Axial Stereogenicity: Catalytic Enantioselective C−N Bond-Forming Cross-Coupling and Catalyst-Controlled Atroposelective Cyclodehydration

(2018) Yongseok Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Aliphatic C—H Oxidations for Late-Stage Functionalization

(2018) M. Christina White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide-Based Catalysts Reach the Outer Sphere through Remote Desymmetrization and Atroposelectivity

(2018) Anthony J. Metrano et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Catalyzed Diaryl Ether Formation from (Hetero)aryl Halides at Low Catalytic Loadings

(2017) Yuntong Zhai et al.   JOURNAL OF ORGANIC CHEMISTRY

Site-Selective, Copper-Mediated O-Arylation of Carbohydrate Derivatives

(2017) Victoria Dimakos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Intermolecular C–O Bond Formation in the Desymmetrization of Diarylmethines Employing a Guanidinylated Peptide-Based Catalyst

(2017) Alex J. Chinn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

(2017) Yong-Bin Wang et al.   Nature Communications

CuI/Oxalamide Catalyzed Couplings of (Hetero)aryl Chlorides and Phenols for Diaryl Ether Formation

(2016) Mengyang Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Distal Stereocontrol Using Guanidinylated Peptides as Multifunctional Ligands: Desymmetrization of Diarylmethanes via Ullman Cross-Coupling

(2016) Byoungmoo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of N–C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

(2016) Motohiro Hirai et al.   ORGANIC LETTERS

Late Stage Azidation of Complex Molecules

(2016) Rashad R. Karimov et al.   ACS Central Science

Copper-Catalyzed Intramolecular Desymmetric Aryl CO Coupling for the Enantioselective Construction of Chiral Dihydrobenzofurans and Dihydrobenzopyrans

(2015) Wenqiang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Enantioselective Synthesis of Spirobilactams through Copper-Catalyzed Intramolecular Double N-Arylation and Phase Separation

(2015) Jianguang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Enantioselective Formation of Cyano-Bearing All-Carbon Quaternary Stereocenters: Desymmetrization by Copper-Catalyzed N-Arylation

(2014) Fengtao Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Tailoring of Teicoplanin with Site-Selective Reactions

(2013) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Enantioselective Intramolecular N-Arylation, an Efficient Method for Kinetic Resolutions

(2013) Wenqiang Yang et al.   ORGANIC LETTERS

The role of organometallic copper(iii) complexes in homogeneous catalysis

(2013) Alicia Casitas et al.   Chemical Science

Site-Selective Bromination of Vancomycin

(2012) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Desymmetric Intramolecular Ullmann C–N Coupling: An Enantioselective Preparation of Indolines

(2012) Fengtao Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Growing Impact of Catalysis in the Pharmaceutical Industry

(2011) Carl A. Busacca et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(I) Enolate Complexes in α-Arylation Reactions: Synthesis, Reactivity, and Mechanism

(2011) Zheng Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper(I) Phenoxide Complexes in the Etherification of Aryl Halides

(2010) Jesse W. Tye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination

(2010) J. L. Gustafson et al.   SCIENCE

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper/Amino Acid Catalyzed Cross-Couplings of Aryl and Vinyl Halides with Nucleophiles†

(2008) Dawei Ma et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis

(2008) Gwilherm Evano et al.   CHEMICAL REVIEWS

Copper Complexes of Anionic Nitrogen Ligands in the Amidation and Imidation of Aryl Halides

(2008) Jesse W. Tye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY