The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

(2021) Yafei Guo et al.   Cell Death & Disease

TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses

(2020) Martina Di Rienzo et al.   CELL DEATH AND DIFFERENTIATION

Gastric microbes associated with gastric inflammation, atrophy and intestinal metaplasia 1 year after Helicobacter pylori eradication

(2020) Joseph J Y Sung et al.   GUT

Therapeutic modulation of inflammasome pathways

(2020) Dhruv Chauhan et al.   IMMUNOLOGICAL REVIEWS

Interplay Between NLRP3 Inflammasome and Autophagy

(2020) Monika Biasizzo et al.   Frontiers in Immunology

The dialogue between the ubiquitin-proteasome system and autophagy: Implications in ageing

(2020) Jia Liang Sun-Wang et al.   AGEING RESEARCH REVIEWS

The Spectrum of Helicobacter-Mediated Diseases

(2020) Karen Robinson et al.   Annual Review of Pathology-Mechanisms of Disease

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition

(2019) Yujia Yuan et al.   CLINICAL SCIENCE

Emerging Activators and Regulators of Inflammasomes and Pyroptosis

(2019) Yansong Xue et al.   TRENDS IN IMMUNOLOGY

Helicobacter pylori Biofilm Formation and Its Potential Role in Pathogenesis

(2018) Skander Hathroubi et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis

(2018) Si Ming Man   Nature Reviews Gastroenterology & Hepatology

Astaxanthin Inhibits Mitochondrial Dysfunction and Interleukin-8 Expression in Helicobacter pylori-Infected Gastric Epithelial Cells

(2018) Suhn Kim et al.   Nutrients

Role of the NLRP3 inflammasome in cancer

(2018) Maryam Moossavi et al.   Molecular Cancer

Unraveling the Novel Protective Effect of Patchouli Alcohol Against Helicobacter pylori-Induced Gastritis: Insights Into the Molecular Mechanism in vitro and in vivo

(2018) Da-wei Lian et al.   Frontiers in Pharmacology

Metabolic regulation of NLRP3

(2017) Mark M. Hughes et al.   IMMUNOLOGICAL REVIEWS

MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis

(2017) S Li et al.   ONCOGENE

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Inflammasomes and Cancer

(2017) Rajendra Karki et al.   Cancer Immunology Research

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells

(2016) Eun A. Ra et al.   Nature Communications

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

(2016) Hui Song et al.   Nature Communications

The MUC1 mucin protects againstHelicobacter pyloripathogenesis in mice by regulation of the NLRP3 inflammasome

(2015) Garrett Z Ng et al.   GUT

Kyoto global consensus report onHelicobacter pylorigastritis

(2015) Kentaro Sugano et al.   GUT

The stomach in health and disease

(2015) R H Hunt et al.   GUT

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Initiation and perpetuation of NLRP3 inflammasome activation and assembly

(2015) Eric I. Elliott et al.   IMMUNOLOGICAL REVIEWS

Helicobacter pylori–specific Protection Against Inflammatory Bowel Disease Requires the NLRP3 Inflammasome and IL-18

(2015) Daniela B. Engler et al.   INFLAMMATORY BOWEL DISEASES

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Negative regulation of NLRP3 inflammasome signaling

(2013) Shuzhen Chen et al.   Protein & Cell

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Gastric cancer

(2009) Henk H Hartgrink et al.   LANCET

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Characterization of TRIM31, upregulated in gastric adenocarcinoma, as a novel RBCC protein

(2008) Takeyuki Sugiura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY