Biocatalytic Enantioselective Synthesis of Atropisomers

The Transformative Power of Biocatalysis in Convergent Synthesis

(2022) Lara E. Zetzsche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocatalytic oxidative cross-coupling reactions for biaryl bond formation

(2022) Lara E. Zetzsche et al.   NATURE

Catalytic Oxidative Coupling of Phenols and Related Compounds

(2022) Jingze Wu et al.   ACS Catalysis

Chemically Driven Rotatory Molecular Machines

(2022) Anirban Mondal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Atropisomeric Biaryls via Chiral Suzuki–Miyaura/Enzymatic Kinetic Resolution

(2022) Matthieu Jouffroy et al.   ACS Catalysis

Directed Evolution of Flavin-Dependent Halogenases for Site- and Atroposelective Halogenation of 3-Aryl-4(3H)-Quinazolinones via Kinetic or Dynamic Kinetic Resolution

(2022) Harrison M. Snodgrass et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetics of enzyme-catalysed desymmetrisation of prochiral substrates: product enantiomeric excess is not always constant

(2021) Peter J Halling   Beilstein Journal of Organic Chemistry

Atropisomerism in diarylamines: structural requirements and mechanisms of conformational interconversion

(2020) Romain Costil et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Broadening the scope of biocatalytic C–C bond formation

(2020) Lara E. Zetzsche et al.   Nature Reviews Chemistry

Desymmetrization of σ-Symmetric Biphenyl-2,6-diyl Diacetate Derivatives by Lipase-Catalyzed Hydrolysis: Unexpected Effect of C(3′)-Substituent on the Enantiotopic Group Selectivity

(2019) Takashi Matsumoto et al.   SYNLETT

Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis

(2019) Carmen Aranda et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantiodivergent Synthesis of Axially Chiral Biphenyls from σ-Symmetric 1,1'-Biphenyl-2,6-diol Derivatives by Single Lipase-Catalyzed Acylative and Hydrolytic Desymmetrization

(2019) Kengo Kasama et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Lipase-Catalyzed Dynamic Kinetic Resolution of C 1 - and C 2 -Symmetric Racemic Axially Chiral 2,2′-Dihydroxy-1,1′-biaryls

(2018) Gamal A. I. Moustafa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic Oxidation Reactions: A Chemist's Perspective

(2018) JiaJia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dirigent proteins in plants: modulating cell wall metabolism during abiotic and biotic stress exposure

(2017) Candelas Paniagua et al.   JOURNAL OF EXPERIMENTAL BOTANY

Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts

(2016) Samantha Staniland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

First Total Synthesis of Dermocanarin 2

(2016) Keisuke Suzuki et al.   SYNLETT

An enantioselective artificial Suzukiase based on the biotin–streptavidin technology

(2016) Anamitra Chatterjee et al.   Chemical Science

Stronger Brønsted Acids: Recent Progress

(2015) Takahiko Akiyama et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Long-Range Bonding/Nonbonding Interactions: A Donor–Acceptor Resonance Studied by Dynamic NMR

(2015) Renzo Ruzziconi et al.   ORGANIC LETTERS

Synthesis, Properties, and Enantiomerization Behavior of Axially Chiral Phenolic Derivatives of 8-(Naphth-1-yl)quinoline and Comparison to 7,7′-Dihydroxy-8,8′-biquinolyl and 1,1′-Bi-2-naphthol

(2015) Paul Blakemore et al.   SYNTHESIS-STUTTGART

Chiral phosphines in nucleophilic organocatalysis

(2014) Yumei Xiao et al.   Beilstein Journal of Organic Chemistry

Enzymatic Desymmetrising Redox Reactions for the Asymmetric Synthesis of Biaryl Atropisomers

(2014) Samantha Staniland et al.   CHEMISTRY-A EUROPEAN JOURNAL

On the lipase-catalyzed resolution of functionalized biaryls

(2013) Benedikt Skrobo et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Total Synthesis of (−)-Euxanmodin B: An Axially Chiral Natural Product with an Anthraquinone-Xanthone Composite Structure

(2011) Nobuyuki Takahashi et al.   Chemistry-An Asian Journal

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biocatalytic Desymmetrization of an Atropisomer with both an Enantioselective Oxidase and Ketoreductases

(2010) Bo Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hindered diarylether and diarylsulfone bisphosphine ligands: atropisomerism and palladium complexes

(2010) Jonathan Clayden et al.   TETRAHEDRON-ASYMMETRY

Atropisomerism at CS Bonds: Asymmetric Synthesis of Diaryl Sulfones by Dynamic Resolution Under Thermodynamic Control

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Synthesis of Tetra-ortho-Substituted Biphenyls by Enzymatic Desymmetrization

(2009) Takashi Matsumoto et al.   SYNLETT

Enantiomerically enriched atropisomeric N,N′-diaryl ureas by oxidative kinetic resolution of their 2-sulfanyl derivatives

(2009) Jonathan Clayden et al.   TETRAHEDRON LETTERS

Enantioselective Synthesis of an Atropisomeric Diaryl Ether

(2008) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed Evolution of Galactose Oxidase: Generation of Enantioselective Secondary Alcohol Oxidases

(2008) Franck Escalettes et al.   CHEMBIOCHEM

De-racemization of Enantiomers versus De-epimerization of Diastereomers-Classification of Dynamic Kinetic Asymmetric Transformations (DYKAT)

(2008) Johannes Steinreiber et al.   CHEMISTRY-A EUROPEAN JOURNAL

Optical resolution of hexamethylbiphenol by cholesterol esterase and porcine pancreas lipase

(2008) Tetsuo Takemura et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

N,N′-Diarylureas: A New Family of Atropisomers Exhibiting Highly Diastereoselective Reactivity

(2008) Jonathan Clayden et al.   JOURNAL OF ORGANIC CHEMISTRY