STAT3 and Its Pathways’ Dysregulation—Underestimated Role in Urological Tumors
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Title
STAT3 and Its Pathways’ Dysregulation—Underestimated Role in Urological Tumors
Authors
Keywords
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Journal
Cells
Volume 11, Issue 19, Pages 3024
Publisher
MDPI AG
Online
2022-09-28
DOI
10.3390/cells11193024
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Note: Only part of the references are listed.- Apoptosis as Driver of Therapy-Induced Cancer Repopulation and Acquired Cell-Resistance (CRAC): A Simple In Vitro Model of Phoenix Rising in Prostate Cancer
- (2022) Francesca Corsi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nuclear expression of pSTAT3Tyr705 and pSTAT3Ser727 in the stromal compartment of localized hormone-naïve prostate cancer.
- (2022) Felicia Marginean et al. PATHOLOGY RESEARCH AND PRACTICE
- Qi Ling decreases paclitaxel resistance in the human prostate cancer by reversing tumor-associated macrophages function
- (2022) Hongwen Cao et al. Aging-US
- CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation
- (2022) Qimei Lin et al. Cell Communication and Signaling
- Importance of STAT3 signalling in cancer, metastasis and therapeutic interventions
- (2022) Mohamed El-Tanani et al. CELLULAR SIGNALLING
- Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4
- (2022) Fan Yang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- S-Adenosylmethionine affects ERK1/2 and STAT3 pathway in androgen-independent prostate cancer cells
- (2022) Thomas Schmidt MOLECULAR BIOLOGY REPORTS
- Traditional Chinese medicine CFF-1 exerts a potent anti-tumor immunity to hinder tumor growth and metastasis in prostate cancer through EGFR/JAK1/STAT3 pathway to inhibit PD-1/PD-L1 checkpoint signaling
- (2022) Yu Zhang et al. PHYTOMEDICINE
- Serum CXCL5 level is associated with tumor progression in penile cancer
- (2021) Miao Mo et al. BIOSCIENCE REPORTS
- miR‑583 inhibits the proliferation and invasion of prostate cancer cells by targeting JAK1
- (2021) Zhongyi Li et al. Molecular Medicine Reports
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer
- (2021) Jeremy J. McGuire et al. Nature Communications
- Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer
- (2021) Kristina Witt et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- LncRNA SNHG1 regulates immune escape of renal cell carcinoma by targeting miR‐129‐3p to activate STAT3 and PD‐L1
- (2021) Pei Tian et al. CELL BIOLOGY INTERNATIONAL
- Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo
- (2021) Malin Hagberg Thulin et al. PROSTATE
- STAT3 phosphorylation is required for the HepaCAM‐mediated inhibition of castration‐resistant prostate cancer cell viability and metastasis
- (2021) Bing Tan et al. PROSTATE
- Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro
- (2021) Chun-Yan Li et al. Cancer Management and Research
- Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer
- (2021) H. H. Peng et al. Frontiers in Genetics
- Cancer Associated Fibroblasts Promote Renal Cancer Progression Through a TDO/Kyn/AhR Dependent Signaling Pathway
- (2021) Li-bo Chen et al. Frontiers in Oncology
- LINC00467 Promotes Prostate Cancer Progression via M2 Macrophage Polarization and the miR-494-3p/STAT3 Axis
- (2021) Hao Jiang et al. Frontiers in Oncology
- Comparing the frequency of CD33 + pSTAT3 + myeloid‐derived suppressor cells and IL‐17 + lymphocytes in patients with prostate cancer and benign prostatic hyperplasia
- (2021) Mohammad‐Javad Sanaei et al. CELL BIOLOGY INTERNATIONAL
- Inhibition of STAT3/PD-L1 and Activation of miR193a-5p Are Critically Involved in Apoptotic Effect of Compound K in Prostate Cancer Cells
- (2021) Jae-Hee Lee et al. Cells
- The metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer
- (2021) Syer C. Lim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT3 as a target for sensitizing prostate cancer cells to irradiation
- (2021) Qu Zhang et al. JOURNAL OF RADIATION RESEARCH
- Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)
- (2021) Sun Yun et al. MOLECULES
- Long non-coding RNA MAGI2-AS3 inactivates STAT3 pathway to inhibit prostate cancer cell proliferation via acting as a microRNA-424-5p sponge
- (2021) Xin Wei et al. Journal of Cancer
- STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications
- (2021) Isidora Tošić et al. NEOPLASIA
- LTF Regulates the Immune Microenvironment of Prostate Cancer Through JAK/STAT3 Pathway
- (2021) Qi Zhao et al. Frontiers in Oncology
- STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy
- (2020) Sruthi V. Hindupur et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting STAT3 enhances NDV‐induced immunogenic cell death in prostate cancer cells
- (2020) Xueke Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
- (2020) Shweta Dambal et al. MOLECULAR CANCER RESEARCH
- Ethacrynic acid inhibits STAT3 activity through the modulation of SHP2 and PTP1B tyrosine phosphatases in DU145 prostate carcinoma cells
- (2020) Yu-Jin Lee et al. BIOCHEMICAL PHARMACOLOGY
- The long non-coding RNA LINC00473 contributes to cell proliferation via JAK-STAT3 signaling pathway by regulating miR-195-5p/SEPT2 axis in prostate cancer
- (2020) Zengshu Xing et al. BIOSCIENCE REPORTS
- Calcitriol inhibits lipopolysaccharide-induced proliferation, migration and invasion of prostate cancer cells through suppressing STAT3 signal activation
- (2020) Wei-Yang Xing et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling
- (2020) Renlun Huang et al. Cell Death & Disease
- Crosstalk between Prostate Cancer Cells and Tumor-Associated Fibroblasts Enhances the Malignancy by Inhibiting the Tumor Suppressor PLZF
- (2020) Kum Hee Noh et al. Cancers
- Treatment of muscle‐invasive and advanced bladder cancer in 2020
- (2020) Vaibhav G. Patel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer
- (2020) Shao-Qian Sun et al. Marine Drugs
- Leptin Promotes Prostate Cancer Proliferation and Migration by Stimulating STAT3 Pathway
- (2020) Amal Gorrab et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- KLF5 inhibits STAT3 activity and tumor metastasis in prostate cancer by suppressing IGF1 transcription cooperatively with HDAC1
- (2020) Jian-Bin Ma et al. Cell Death & Disease
- Serum CXCL13 Level is Associated with Tumor Progression and Unfavorable Prognosis in Penile Cancer
- (2020) Miao Mo et al. OncoTargets and Therapy
- STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population
- (2020) Giacomo Canesin et al. Scientific Reports
- Epidemiology, clinical presentation, and evaluation of upper-tract urothelial carcinoma
- (2020) Firas G. Petros Translational Andrology and Urology
- LncRNA CARLo-7 facilitates proliferation, migration, invasion, and EMT of bladder cancer cells by regulating Wnt/β-catenin and JAK2/STAT3 signaling pathways
- (2020) Houfeng Huang et al. Translational Andrology and Urology
- LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway
- (2020) Young Yun Jung et al. JOURNAL OF CELLULAR PHYSIOLOGY
- STAT3 enhances radiation-induced tumor migration, invasion and stem-like properties of bladder cancer
- (2020) Fang Wang et al. Molecular Medicine Reports
- Comparative STAT3-Regulated Gene Expression Profile in Renal Cell Carcinoma Subtypes
- (2019) Rebekah L. Robinson et al. Frontiers in Oncology
- Expression of tSTAT3, pSTAT3 727 , and pSTAT3 705 in the epithelial cells of hormone‐naïve prostate cancer
- (2019) Agnieszka Krzyzanowska et al. PROSTATE
- PLCε promotes urinary bladder cancer cells proliferation through STAT3/LDHA pathway‑mediated glycolysis
- (2019) Honglin Cheng et al. ONCOLOGY REPORTS
- Retinoic acid-related orphan receptor C regulates proliferation, glycolysis, and chemoresistance via the PD-L1/ITGB6/STAT3 signaling axis in bladder cancer
- (2019) Dalong Cao et al. CANCER RESEARCH
- Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
- (2019) Cassandra Ringuette Goulet et al. BMC CANCER
- STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells
- (2019) Rossana Cocchiola et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Interleukin 6 signaling maintains the stem-like properties of bladder cancer stem cells
- (2019) Hua Wei Translational Cancer Research
- The STAT3 inhibitor galiellalactone inhibits the generation of MDSC‐like monocytes by prostate cancer cells and decreases immunosuppressive and tumorigenic factors
- (2019) Rebecka Hellsten et al. PROSTATE
- LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling
- (2019) Jie Luo et al. Nature Communications
- Signal transducer and activator of transcription-3 drives the high-fat diet-associated prostate cancer growth
- (2019) Hiu Yee Kwan et al. Cell Death & Disease
- Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome
- (2019) Gatta et al. Cancers
- GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism
- (2019) Qianqian Shi et al. CANCER GENE THERAPY
- Calcitriol inhibits migration and invasion of RCC cells through suppressing Smad2/3‐, STAT3 and β‐catenin‐ mediated EMT
- (2019) Shen Xu et al. CANCER SCIENCE
- Glutamine affects T24 bladder cancer cell proliferation by activating STAT3 through ROS and glutaminolysis
- (2019) Ningchuan Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The global burden of urinary bladder cancer: an update
- (2019) Anke Richters et al. WORLD JOURNAL OF UROLOGY
- Structural Implications of STAT3 and STAT5 SH2 Domain Mutations
- (2019) Elvin D. de Araujo et al. Cancers
- miR‐4500 suppresses cell proliferation and migration in bladder cancer via inhibition of STAT3/CCR7 pathway
- (2019) Wei Peng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Methyllucidone inhibits STAT3 activity by regulating the expression of the protein tyrosine phosphatase MEG2 in DU145 prostate carcinoma cells
- (2018) Yena Jin et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Piperlongumine derivative, CG-06 , inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells
- (2018) Young Hwan Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Docetaxel-mediated autophagy promotes chemoresistance in castration-resistant prostate cancer cells by inhibiting STAT3
- (2018) Fei Hu et al. CANCER LETTERS
- ASC-J9 ® suppresses prostate cancer cell invasion via altering the sumoylation-phosphorylation of STAT3
- (2018) WanYing Lin et al. CANCER LETTERS
- The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion
- (2018) Swadesh K. Das et al. CANCER RESEARCH
- STAT3: a multifaceted oncoprotein
- (2018) Aleks C. Guanizo et al. GROWTH FACTORS
- Regulation of immunophenotype modulation of monocytes-macrophages from M1 into M2 by prostate cancer cell-culture supernatant via transcription factor STAT3
- (2018) R. Solís-Martínez et al. IMMUNOLOGY LETTERS
- Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells
- (2018) Yangyang He et al. International Journal of Medical Sciences
- Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development
- (2018) Jacopo Sgrignani et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels
- (2018) LiJun Xu et al. Molecular Oncology
- G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas
- (2018) Yong Wang et al. Cell Death & Disease
- Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties
- (2018) Yong-qing Liu et al. ACTA PHARMACOLOGICA SINICA
- The diagnosis and treatment of penile cancer
- (2018) Oliver Walther Hakenberg et al. Deutsches Arzteblatt International
- STAT3 expression is a prognostic marker in upper urinary tract urothelial carcinoma
- (2018) Kyosuke Matsuzaki et al. PLoS One
- 2′-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation
- (2018) Yae Jin Yoon et al. CANCER SCIENCE
- STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers
- (2018) Dayson Moreira et al. CLINICAL CANCER RESEARCH
- miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladder cancer
- (2018) Qiangqiang Ge et al. INTERNATIONAL JOURNAL OF CANCER
- IL-8 Secreted from M2 Macrophages Promoted Prostate Tumorigenesis via STAT3/MALAT1 Pathway
- (2018) Tingjin Zheng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Atractylenolide II Induces Apoptosis of Prostate Cancer Cells through Regulation of AR and JAK2/STAT3 Signaling Pathways
- (2018) Jing Wang et al. MOLECULES
- Galiellalactone inhibits the STAT3/AR signaling axis and suppresses Enzalutamide-resistant Prostate Cancer
- (2018) Daksh Thaper et al. Scientific Reports
- Loss of Nuclear Functions of HOXA10 Is Associated With Testicular Cancer Proliferation
- (2018) Ruiqi Chen et al. Frontiers in Oncology
- Overexpression of Indoleamine 2,3-Dioxygenase 1 Promotes Epithelial-Mesenchymal Transition by Activation of the IL-6/STAT3/PD-L1 Pathway in Bladder Cancer
- (2018) Wentao Zhang et al. Translational Oncology
- Over-expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Poor Prognosis in Upper Tract Urothelial Carcinoma
- (2017) Wei-Ming Li et al. International Journal of Medical Sciences
- Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Modulation of STAT3-CCL2 Signaling
- (2017) Sung-Ying Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- EZH2 enhances the invasive capability of renal cell carcinoma cells via activation of STAT3
- (2017) Dong Zhang et al. Molecular Medicine Reports
- IL-8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF-κB pathway in prostate cancer
- (2017) Yidi Guo et al. Molecular Medicine Reports
- STAT3 inhibition by WP1066 suppresses the growth and invasiveness of bladder cancer cells
- (2017) Yujiro Tsujita et al. ONCOLOGY REPORTS
- Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT
- (2017) Qiuli Liu et al. Cell Death & Disease
- IL-6 is involved in malignancy and doxorubicin sensitivity of renal carcinoma cells
- (2017) Yanqiang Chen et al. Cell Adhesion & Migration
- Socioeconomic factors and penile cancer risk and mortality; a population-based study
- (2016) Christian Torbrand et al. BJU INTERNATIONAL
- STAT3 polymorphism rs4796793 may be a predictive factor of tumor response to multiple tyrosine kinase inhibitors in metastatic renal cell carcinoma in Japanese population
- (2016) Kazuhiro Yamamoto et al. MEDICAL ONCOLOGY
- Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC)
- (2016) Francesco Soria et al. WORLD JOURNAL OF UROLOGY
- Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer
- (2016) Jong Hyun Lee et al. Oncotarget
- Epidemiology of Prostate and Testicular Cancer
- (2016) James Ferguson et al. SEMINARS IN INTERVENTIONAL RADIOLOGY
- Association of Single Nucleotide Polymorphisms in STAT3 with Hand-Foot Skin Reactions in Patients with Metastatic Renal Cell Carcinoma Treated with Multiple Tyrosine Kinase Inhibitors: A Retrospective Analysis in Japanese Patients
- (2015) Kazuhiro Yamamoto et al. Targeted Oncology
- STAT3 regulated ARF expression suppresses prostate cancer metastasis
- (2015) Jan Pencik et al. Nature Communications
- Drug Resistance via Feedback Activation of Stat3 in Oncogene-Addicted Cancer Cells
- (2014) Ho-June Lee et al. CANCER CELL
- HAVCR/KIM-1 Activates the IL-6/STAT-3 Pathway in Clear Cell Renal Cell Carcinoma and Determines Tumor Progression and Patient Outcome
- (2014) T. Cuadros et al. CANCER RESEARCH
- Role of STAT3 in Cancer Metastasis and Translational Advances
- (2013) Mohammad Zahid Kamran et al. Biomed Research International
- Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression
- (2012) Toshiki Oguro et al. EUROPEAN JOURNAL OF CANCER
- STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma
- (2010) A Horiguchi et al. BRITISH JOURNAL OF CANCER
- Is Stat3 and/or p53 mRNA expression a prognostic marker for renal cell carcinoma?
- (2009) Akinori Masuda et al. BIOMEDICAL RESEARCH-TOKYO
- Expression of Signal Transducer and Activator of Transcription 3 and Suppressor of Cytokine Signaling 3 in Urothelial Carcinoma
- (2009) Wan-Ting Huang et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival
- (2008) Chun-Liang Chen et al. Molecular Cancer
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