Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties

Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A

(2018) Qingqing Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cancer statistics, 2016

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EC-70124, a Novel Glycosylated Indolocarbazole Multikinase Inhibitor, Reverts Tumorigenic and Stem Cell Properties in Prostate Cancer by Inhibiting STAT3 and NF- B

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Reversal of the multidrug resistance of human ileocecal adenocarcinoma cells by acetyl-11-keto-β-boswellic acid via downregulation of P-glycoprotein signals

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Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression

(2015) Adrian P. Rybak et al.   Oncotarget

IGF-1R inhibition potentiates cytotoxic effects of chemotherapeutic agents in early stages of chemoresistant ovarian cancer cells

(2014) Ram K. Singh et al.   CANCER LETTERS

Cancer Stem Cells in Prostate Cancer Chemoresistance

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Regulation of SOD2 and β-arrestin1 by interleukin-6 contributes to the increase of IGF-1R expression in docetaxel resistant prostate cancer cells

(2014) Denglu Zhang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

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Generation of Prostate Tumor-Initiating Cells Is Associated with Elevation of Reactive Oxygen Species and IL-6/STAT3 Signaling

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Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature

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Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells

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Docetaxel

(2012) Kate McKeage   DRUGS

Chemoprevention of intestinal adenomatous polyposis by acetyl-11-keto-beta-boswellic acid inAPCMin/+mice

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EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

(2012) Sandeep Singh et al.   Molecular Cancer

Retigeric Acid B Exhibits Antitumor Activity through Suppression of Nuclear Factor-κB Signaling in Prostate Cancer Cells in Vitro and in Vivo

(2012) Yong-Qing Liu et al.   PLoS One

Boswellia serrata

(2011) Mona Abdel-Tawab et al.   CLINICAL PHARMACOKINETICS

Pathways of chemotherapy resistance in castration-resistant prostate cancer

(2011) K. L. Mahon et al.   ENDOCRINE-RELATED CANCER

Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species

(2011) Santhi Achuthan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug resistance in metastatic castration-resistant prostate cancer

(2010) Bostjan Seruga et al.   Nature Reviews Clinical Oncology

Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells

(2010) Chul-Ho Jeong et al.   STEM CELLS

Inhibitory effect of acetyl-11-keto-β-boswellic acid on androgen receptor by interference of Sp1 binding activity in prostate cancer cells

(2008) Hui-Qing Yuan et al.   BIOCHEMICAL PHARMACOLOGY

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell

Prostate Cancer Stem Cells: A New Target for Therapy

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