Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Prostate cancer

(2016) Gerhardt Attard et al.   LANCET

Natural product pectolinarigenin inhibits osteosarcoma growth and metastasis via SHP-1-mediated STAT3 signaling inhibition

(2016) Tao Zhang et al.   Cell Death & Disease

Flavonoids, Flavonoid Subclasses, and Esophageal Cancer Risk: A Meta-Analysis of Epidemiologic Studies

(2016) Lingling Cui et al.   Nutrients

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

(2016) Daniel P. Ball et al.   Oncotarget

Estimates of alcohol-related oesophageal cancer burden in Japan: systematic review and meta-analyses

(2015) Michael Roerecke et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6

(2015) Kang Lu et al.   CANCER LETTERS

Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells

(2015) Jaemoo Chun et al.   CANCER LETTERS

Phase 1 and pharmacological trial of OPB-31121, a signal transducer and activator of transcription-3 inhibitor, in patients with advanced hepatocellular carcinoma

(2015) Takuji Okusaka et al.   HEPATOLOGY RESEARCH

Ponicidin Induces Apoptosis via JAK2 and STAT3 Signaling Pathways in Gastric Carcinoma

(2015) Yuan-Fei Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma

(2014) W.-T. Tai et al.   CLINICAL CANCER RESEARCH

Natural products and their derivatives regulating the janus kinase/signal transducer and activator of transcription pathway

(2014) Yuan Lin et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Evolution of androgen receptor targeted therapy for advanced prostate cancer

(2014) Yien Ning Sophia Wong et al.   Nature Reviews Clinical Oncology

Oral Astaxanthin Supplementation Prevents Peritoneal Fibrosis in Rats

(2014) K. Wakabayashi et al.   PERITONEAL DIALYSIS INTERNATIONAL

Astaxanthin Treatment Confers Protection against Oxidative Stress in U937 Cells Stimulated with Lipopolysaccharide Reducing O2− Production

(2014) Sara Franceschelli et al.   PLoS One

Astaxanthin Inhibits JAK/STAT-3 Signaling to Abrogate Cell Proliferation, Invasion and Angiogenesis in a Hamster Model of Oral Cancer

(2014) J. Kowshik et al.   PLoS One

Consumption of red and processed meat and risk for esophageal squamous cell carcinoma based on a meta-analysis

(2013) Xudong Qu et al.   ANNALS OF EPIDEMIOLOGY

Poultry and fish intake and risk of esophageal cancer: A meta-analysis of observational studies

(2013) Gengxi Jiang et al.   Asia-Pacific Journal of Clinical Oncology

Carotenoid Intake and Esophageal Cancer Risk: a Meta-analysis

(2013) Xiao-Xiao Ge et al.   Asian Pacific Journal of Cancer Prevention

Central Adiposity Is Associated With Increased Risk of Esophageal Inflammation, Metaplasia, and Adenocarcinoma: A Systematic Review and Meta-analysis

(2013) Siddharth Singh et al.   Clinical Gastroenterology and Hepatology

The role of Stat3 in glioblastoma multiforme

(2013) Rodney B. Luwor et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Meat, fish, and esophageal cancer risk: a systematic review and dose-response meta-analysis

(2013) Maryam Salehi et al.   NUTRITION REVIEWS

Brevilin A, a Novel Natural Product, Inhibits Janus Kinase Activity and Blocks STAT3 Signaling in Cancer Cells

(2013) Xing Chen et al.   PLoS One

Astaxanthin Treatment Reduced Oxidative Induced Pro-Inflammatory Cytokines Secretion in U937: SHP-1 as a Novel Biological Target

(2012) Lorenza Speranza et al.   Marine Drugs

Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells

(2011) Xia Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Progress of molecular targeted therapies for prostate cancers

(2011) Weihua Fu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Astaxanthin Induces Mitochondria-Mediated Apoptosis in Rat Hepatocellular Carcinoma CBRH-7919 Cells

(2011) Xiao-dong Song et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

(2011) Li Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumorigenic potential of STAT3 alternative splicing modulation

(2011) F. Zammarchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What made sesquiterpene lactones reach cancer clinical trials?

(2010) Akram Ghantous et al.   DRUG DISCOVERY TODAY

Inhibition of STAT3 and ErbB2 Suppresses Tumor Growth, Enhances Radiosensitivity, and Induces Mitochondria-Dependent Apoptosis in Glioma Cells

(2010) Ling Gao et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

(2010) Kil-Nam Kim et al.   TOXICOLOGY IN VITRO

Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells

(2009) Paola Palozza et al.   CANCER LETTERS

Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2

(2009) Ponnuraj Nagendraprabhu et al.   INVESTIGATIONAL NEW DRUGS

Stat3 Promotes Metastatic Progression of Prostate Cancer

(2008) Junaid Abdulghani et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS