ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
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Title
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
Authors
Keywords
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Journal
Frontiers in Cellular Neuroscience
Volume 16, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-08-31
DOI
10.3389/fncel.2022.963169
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Note: Only part of the references are listed.- Little Helpers or Mean Rogue—Role of Microglia in Animal Models of Amyotrophic Lateral Sclerosis
- (2021) Hilal Cihankaya et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Phosphorylated Form of the Histone H2AX (γH2AX) in the Brain from Embryonic Life to Old Age
- (2021) Adalberto Merighi et al. MOLECULES
- Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis
- (2021) Jan Stein et al. Oxidative Medicine and Cellular Longevity
- DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
- (2020) Byung Woo Kim et al. Acta Neuropathologica Communications
- Caffeine and NAD+ Improve Motor Neural Integrity of Dissociated Wobbler Cells In Vitro
- (2020) Mareike Zwilling et al. Antioxidants
- A combined γ-H2AX and 53BP1 approach to determine the DNA damage-repair response to exercise in hypoxia
- (2020) Josh Williamson et al. FREE RADICAL BIOLOGY AND MEDICINE
- Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations
- (2020) Anna Konopka et al. Molecular Neurodegeneration
- [Corrigendum] MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro
- (2020) Chen-Xing Ji et al. ONCOLOGY REPORTS
- Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis
- (2019) Francesca De Giorgio et al. Disease Models & Mechanisms
- Edaravone for the treatment of amyotrophic lateral sclerosis
- (2019) Hiide Yoshino Expert Review of Neurotherapeutics
- Hydrogen peroxide, a potent inducer of global genomic instability
- (2019) Lei Qi et al. CURRENT GENETICS
- Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
- (2019) Anju Singh et al. MOLECULES
- Early neuronal accumulation of DNA double strand breaks in Alzheimer’s disease
- (2019) Niraj M. Shanbhag et al. Acta Neuropathologica Communications
- Aberrations in Oxidative Stress Markers in Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis
- (2019) Zihao Wang et al. Oxidative Medicine and Cellular Longevity
- Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis
- (2019) Klatt et al. Cells
- Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
- (2019) Oliver H. Tam et al. Cell Reports
- ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
- (2019) Rita Mejzini et al. Frontiers in Neuroscience
- N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why
- (2018) Giancarlo Aldini et al. FREE RADICAL RESEARCH
- Neuroprotective effects of N-acetyl cysteine on primary hippocampus neurons against hydrogen peroxide-induced injury are mediated via inhibition of mitogen-activated protein kinases signal transduction and antioxidative action
- (2018) Wei Wu et al. Molecular Medicine Reports
- Increased ROS Level in Spinal Cord of Wobbler Mice due to Nmnat2 Downregulation
- (2018) Pascal Röderer et al. MOLECULAR NEUROBIOLOGY
- Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells
- (2018) Tong Chen et al. NEUROCHEMISTRY INTERNATIONAL
- Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy
- (2018) Annapoorna Kannan et al. NUCLEIC ACIDS RESEARCH
- Catalase and its mysteries
- (2018) Hessam Sepasi Tehrani et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis
- (2018) Urbain Weyemi et al. Nature Communications
- 8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
- (2018) Xueqing Ba et al. Redox Biology
- Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs
- (2018) Manoj Kumar Jaiswal MEDICINAL RESEARCH REVIEWS
- ROS and the DNA damage response in cancer
- (2018) Upadhyayula Sai Srinivas et al. Redox Biology
- Sequential molecular changes and dynamic oxidative stress in high-grade serous ovarian carcinogenesis
- (2017) Hiroshi Kobayashi et al. FREE RADICAL RESEARCH
- The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis
- (2017) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis
- (2017) Zhang-Yu Zou et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- The role of mitochondria in amyotrophic lateral sclerosis
- (2017) Emma F. Smith et al. NEUROSCIENCE LETTERS
- Amyotrophic Lateral Sclerosis
- (2017) Robert H. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?
- (2017) Dmitry Petrov et al. Frontiers in Aging Neuroscience
- Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity
- (2016) Kuo Du et al. ARCHIVES OF TOXICOLOGY
- Mitochondria-targeted antioxidant mitotempo protects mitochondrial function against amyloid beta toxicity in primary cultured mouse neurons
- (2016) Hongtao Hu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Spatiotemporal Pattern of Degeneration in the Cerebellum of the Wobbler Mouse
- (2016) Darius Saberi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Amyotrophic lateral sclerosis: moving towards a new classification system
- (2016) Ammar Al-Chalabi et al. LANCET NEUROLOGY
- γ-H2AX responds to DNA damage induced by long-term exposure to combined low-dose-rate neutron and γ-ray radiation
- (2016) Junlin Zhang et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders
- (2016) Md. Torequl Islam NEUROLOGICAL RESEARCH
- Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons
- (2016) Rodrigo Lopez-Gonzalez et al. NEURON
- Implementation of a manual for working with wobbler mice and criteria for discontinuation of the experiment
- (2015) Bastian Ott et al. ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
- Regulation of catalase expression in healthy and cancerous cells
- (2015) Christophe Glorieux et al. FREE RADICAL BIOLOGY AND MEDICINE
- Neuroprotective effect of ultra-high dose methylcobalamin in wobbler mouse model of amyotrophic lateral sclerosis
- (2015) Ken Ikeda et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Edaravone, a Free Radical Scavenger, Delayed Symptomatic and Pathological Progression of Motor Neuron Disease in the Wobbler Mouse
- (2015) Ken Ikeda et al. PLoS One
- Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice
- (2015) Lin Lu et al. PLoS One
- Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons
- (2014) Debolina Ghosh et al. AGING CELL
- Phosphorylation of Histone H2AX in the Mouse Brain from Development to Senescence
- (2014) Serena Barral et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nucleosomes Suppress the Formation of Double-strand DNA Breaks during Attempted Base Excision Repair of Clustered Oxidative Damages
- (2014) Wendy J. Cannan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice
- (2014) E. A. Winkler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rotenone Induction of Hydrogen Peroxide Inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E Pathways, Leading to Neuronal Apoptosis
- (2014) Qian Zhou et al. TOXICOLOGICAL SCIENCES
- Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients
- (2014) Koji Abe et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- DNA repair mechanisms in dividing and non-dividing cells
- (2013) Teruaki Iyama et al. DNA REPAIR
- Impaired Glutathione Synthesis in Neurodegeneration
- (2013) Koji Aoyama et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of mitochondrial DNA mutations and free radicals in disease and ageing
- (2013) M. Lagouge et al. JOURNAL OF INTERNAL MEDICINE
- The wobbler mouse, an ALS animal model
- (2013) Jakob Maximilian Moser et al. MOLECULAR GENETICS AND GENOMICS
- Modulation of oxidative stress as an anticancer strategy
- (2013) Chiara Gorrini et al. NATURE REVIEWS DRUG DISCOVERY
- Double-strand break repair: 53BP1 comes into focus
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits
- (2013) Gordon F. Rushworth et al. PHARMACOLOGY & THERAPEUTICS
- The critical role of catalase in prooxidant and antioxidant function of p53
- (2012) M Y Kang et al. CELL DEATH AND DIFFERENTIATION
- Radiation-induced double strand breaks and subsequent apoptotic DNA fragmentation in human peripheral blood mononuclear cells
- (2012) Marjan Moreels INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Progesterone prevents mitochondrial dysfunction in the spinal cord of wobbler mice
- (2012) Maria Claudia Gonzalez Deniselle et al. JOURNAL OF NEUROCHEMISTRY
- Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1
- (2012) Travis Rush et al. NEUROTOXICOLOGY
- Morphological Characteristics of Motor Neurons Do Not Determine Their Relative Susceptibility to Degeneration in a Mouse Model of Severe Spinal Muscular Atrophy
- (2012) Sophie R. Thomson et al. PLoS One
- Reactive oxygen species: from health to disease
- (2012) K Brieger et al. SWISS MEDICAL WEEKLY
- Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases
- (2012) William M. Johnson et al. Nutrients
- A novelDrosophilaSOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease
- (2012) Alicia M. Celotto et al. Brain and Behavior
- Amyotrophic lateral sclerosis
- (2011) Matthew C Kiernan et al. LANCET
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- γH2AX: a sensitive molecular marker of DNA damage and repair
- (2010) L-J Mah et al. LEUKEMIA
- Regulation of superoxide dismutase genes: Implications in disease
- (2009) Lu Miao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
- A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria
- (2008) Jan Trnka et al. FREE RADICAL BIOLOGY AND MEDICINE
- Redox-based regulation of signal transduction: Principles, pitfalls, and promises
- (2008) Yvonne M.W. Janssen-Heininger et al. FREE RADICAL BIOLOGY AND MEDICINE
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