Sequential molecular changes and dynamic oxidative stress in high-grade serous ovarian carcinogenesis

Distinct molecular landscapes between endometrioid and nonendometrioid uterine carcinomas

(2017) Nathaniel L. Jones et al.   INTERNATIONAL JOURNAL OF CANCER

Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway

(2017) Rachana Garg et al.   Cell Reports

Secretory cell outgrowths, p53 signatures, and serous tubal intraepithelial carcinoma in the fallopian tubes of patients with sporadic pelvic serous carcinoma

(2016) Radhika Srinivasan et al.   Indian Journal of Pathology and Microbiology

CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma

(2016) Elisabetta Kuhn et al.   MODERN PATHOLOGY

PAX2 function, regulation and targeting in fallopian tube-derived high-grade serous ovarian cancer

(2016) D A Modi et al.   ONCOGENE

Detection of serous precursor lesions in resected fallopian tubes from patients with benign diseases and a relatively low risk for ovarian cancer

(2016) Naoyo Nishida et al.   PATHOLOGY INTERNATIONAL

Potential scenarios leading to ovarian cancer arising from endometriosis

(2016) Hiroshi Kobayashi   REDOX REPORT

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

(2016) Thomas E. Bartlett et al.   Nature Communications

Aldehyde dehydrogenase 1A1 in stem cells and cancer

(2016) Hiroyuki Tomita et al.   Oncotarget

Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways

(2016) Tushar Tomar et al.   Genome Medicine

Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis

(2016) Stav Sapoznik et al.   NEOPLASIA

Divergent Roles of PAX2 in the Etiology and Progression of Ovarian Cancer

(2015) E. M. Al-Hujaily et al.   Cancer Prevention Research

Targeting EZH2 for Cancer Therapy: Progress and Perspective

(2015) Chi Han Li et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer

(2015) S Shigeta et al.   ONCOGENE

Oxidative Stress and Antioxidant Defense in Endometriosis and Its Malignant Transformation

(2015) Takuya Iwabuchi et al.   Oxidative Medicine and Cellular Longevity

Analysis of 1,115 Patients Tested for MET Amplification and Therapy Response in the MD Anderson Phase I Clinic

(2014) D. L. F. Jardim et al.   CLINICAL CANCER RESEARCH

Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - an update

(2014) Felix Zeppernick et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium

(2014) Gang Ning et al.   JOURNAL OF PATHOLOGY

Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma

(2014) M Herman Chui et al.   MODERN PATHOLOGY

Type I to Type II Ovarian Carcinoma Progression

(2013) Rong Wu et al.   AMERICAN JOURNAL OF PATHOLOGY

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models

(2013) Ruth Perets et al.   CANCER CELL

Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube-Derived High-Grade Serous Ovarian Cancers

(2013) A. M. Karst et al.   CANCER RESEARCH

Secretory cell expansion with aging: Risk for pelvic serous carcinogenesis

(2013) Jie Li et al.   GYNECOLOGIC ONCOLOGY

The Stem-Cell Profile of Ovarian Surface Epithelium is Reproduced in the Oviductal Fimbriae, with Increased Stem-Cell Marker Density in Distal Parts of the Fimbriae

(2013) Nelly Auersperg   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Deregulation of PAX2 expression in renal cell tumours: mechanisms and potential use in differential diagnosis

(2013) Patrícia Patrício et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular Mechanisms Linking Endometriosis Under Oxidative Stress With Ovarian Tumorigenesis and Therapeutic Modalities

(2012) Hiroshi Shigetomi et al.   CANCER INVESTIGATION

Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer

(2012) Ludmila Szabova et al.   CANCER RESEARCH

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

(2012) Kathryn M. Kinross et al.   JOURNAL OF CLINICAL INVESTIGATION

Fenton Reaction Induced Cancer in Wild Type Rats Recapitulates Genomic Alterations Observed in Human Cancer

(2012) Shinya Akatsuka et al.   PLoS One

The Genomic Landscape of TP53 and p53 Annotated High Grade Ovarian Serous Carcinomas from a Defined Founder Population Associated with Patient Outcome

(2012) Paulina M. Wojnarowicz et al.   PLoS One

High-grade serous ovarian cancer arises from fallopian tube in a mouse model

(2012) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets

(2012) Yuchun Luo et al.   STEM CELLS

EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling

(2011) Chun-Ju Chang et al.   CANCER CELL

The impact of ovulation on fallopian tube epithelial cells: evaluating three hypotheses connecting ovulation and serous ovarian cancer

(2011) Shelby M King et al.   ENDOCRINE-RELATED CANCER

Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas

(2011) Alison M. Karst et al.   GYNECOLOGIC ONCOLOGY

EZH2 and ALDH-1 mark breast epithelium at risk for breast cancer development

(2011) Lakshmi P Kunju et al.   MODERN PATHOLOGY

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo

(2011) L K Mullany et al.   ONCOGENE

PAX2 Regulates ADAM10 Expression and Mediates Anchorage-Independent Cell Growth of Melanoma Cells

(2011) Sophia Boyoung Lee et al.   PLoS One

Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells

(2010) T-Y Jeon et al.   BRITISH JOURNAL OF CANCER

Value of integrated positron emission tomography revised using a phantom study to evaluate malignancy grade of lung adenocarcinoma

(2010) Haruhiko Nakayama et al.   CANCER

ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

(2010) Kimberly C. Wiegand et al.   NEW ENGLAND JOURNAL OF MEDICINE

Iron: An emerging factor in colorectal carcinogenesis

(2010) Anita CG Chua   WORLD JOURNAL OF GASTROENTEROLOGY

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression

(2009) Rachna Sehgal et al.   DEVELOPMENTAL BIOLOGY

Conditional Inactivation of Brca1, p53 and Rb in Mouse Ovaries Results in the Development of Leiomyosarcomas

(2009) Katherine V. Clark-Knowles et al.   PLoS One

Induction of Ovarian Leiomyosarcomas in Mice by Conditional Inactivation of Brca1 and p53

(2009) Bridget A. Quinn et al.   PLoS One

Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective

(2008) E A Jarboe et al.   HISTOPATHOLOGY

Serous Tubal Intraepithelial Carcinoma: Its Potential Role in Primary Peritoneal Serous Carcinoma and Serous Cancer Prevention

(2008) Joseph W. Carlson et al.   JOURNAL OF CLINICAL ONCOLOGY