Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons

Published 2016 View Full Article

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Title
Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons
Authors
Keywords
ALS, C9ORF72, DNA damage, DPR, FTD, iPSC, mitochondria, oxidative stress, RAN translation, repeats
Journal
NEURON
Volume 92, Issue 2, Pages 383-391
Publisher
Elsevier BV
Online
2016-10-10
DOI
10.1016/j.neuron.2016.09.015

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