N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why

Assessment of glutathione/glutathione disulphide ratio and S -glutathionylated proteins in human blood, solid tissues, and cultured cells

(2017) Daniela Giustarini et al.   FREE RADICAL BIOLOGY AND MEDICINE

N-acetylcysteine attenuates the cuprizone-induced behavioral changes and oligodendrocyte loss in male C57BL/7 mice via its anti-inflammation actions

(2017) Lin Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Antioxidant Treatment Reduces Formation of Structural Cores and Improves Muscle Function in RYR1Y522S/WT Mice

(2017) Antonio Michelucci et al.   Oxidative Medicine and Cellular Longevity

Revisiting the reactions of superoxide with glutathione and other thiols

(2016) Christine C. Winterbourn   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Comparison of N-acetylcysteine and cysteine in their ability to replenish intracellular cysteine by a specific fluorescent probe

(2016) Xinyuan He et al.   CHEMICAL COMMUNICATIONS

N-acetylcysteine attenuates intrauterine growth retardation-induced hepatic damage in suckling piglets by improving glutathione synthesis and cellular homeostasis

(2016) Hao Zhang et al.   EUROPEAN JOURNAL OF NUTRITION

High-Throughput UPLC–MS Method for the Determination ofN-Acetyl-l-Cysteine: Application in Tissue Distribution Study in Wistar Rats

(2016) Masoom Raza Siddiqui et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs

(2015) Takujiro Homma et al.   CURRENT DRUG METABOLISM

Glutathione redox imbalance in brain disorders

(2015) Feng Gu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status

(2015) Jie Zhou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels

(2015) Shaopeng Yuan et al.   Science Translational Medicine

Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach

(2014) Corin Storkey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Disulfide stress: a novel type of oxidative stress in acute pancreatitis

(2014) Mari-Luz Moreno et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds

(2014) Giancarlo Aldini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Scavenging rate constants of hydrophilic antioxidants against multiple reactive oxygen species

(2014) Yoshimi Sueishi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The Glutathione System: A New Drug Target in Neuroimmune Disorders

(2014) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Cys34-Cysteinylated Human Serum Albumin Is a Sensitive Plasma Marker in Oxidative Stress-Related Chronic Diseases

(2014) Kohei Nagumo et al.   PLoS One

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Kinetic and mechanistic considerations to assess the biological fate of peroxynitrite

(2013) Sebastián Carballal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The thiol pool in human plasma: The central contribution of albumin to redox processes

(2013) Lucía Turell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products

(2013) Giancarlo Aldini et al.   FREE RADICAL RESEARCH

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation

(2013) G. Vistoli et al.   FREE RADICAL RESEARCH

N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells

(2013) Ming-Shun Wu et al.   MOLECULAR CARCINOGENESIS

Redox Albuminomics: Oxidized Albumin in Human Diseases

(2012) Graziano Colombo et al.   ANTIOXIDANTS & REDOX SIGNALING

Kinetics and Mechanisms of Thiol–Disulfide Exchange Covering Direct Substitution and Thiol Oxidation-Mediated Pathways

(2012) Péter Nagy   ANTIOXIDANTS & REDOX SIGNALING

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

(2012) Marcel Deponte   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Preventive effect of N-acetyl-L-cysteine on oxidative stress and cognitive impairment in hepatic encephalopathy following bile ductligation

(2012) Saurabh Dhanda et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human serum albumin cysteinylation is increased in end stage renal disease patients and reduced by hemodialysis: mass spectrometry studies

(2012) L. Regazzoni et al.   FREE RADICAL RESEARCH

Interaction of N-acetylcysteine and Cysteine in Human Plasma

(2012) Kendra K. Radtke et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Targeting maladaptive glutathione responses in lung disease

(2010) Neal S. Gould et al.   BIOCHEMICAL PHARMACOLOGY

N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death

(2010) Jie Zheng et al.   CANCER LETTERS

3-chlorotyrosine in Sputum of COPD Patients: Relationship with Airway Inflammation

(2010) Charles O’Donnell et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Antioxidant and free radical scavenging properties of N-acetylcysteine amide (NACA) and comparison with N-acetylcysteine (NAC)

(2008) Burhan Ates et al.   FREE RADICAL RESEARCH

A tandem MS precursor-ion scan approach to identify variable covalent modification of albumin Cys34: a new tool for studying vascular carbonylation

(2008) Giancarlo Aldini et al.   JOURNAL OF MASS SPECTROMETRY