SIK2 protects against renal tubular injury and the progression of diabetic kidney disease

Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics

(2021) Qinjie Weng et al.   Nature Communications

Deficiency of mitochondrial glycerol 3-phosphate dehydrogenase exacerbates podocyte injury and the progression of diabetic kidney disease

(2021) Hua Qu et al.   DIABETES

Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury

(2020) Wenjuan Jiang et al.   Frontiers in Immunology

Natural antioxidants' effects on endoplasmic reticulum stress-related diseases

(2020) Laura María Reyes-Fermín et al.   FOOD AND CHEMICAL TOXICOLOGY

Vancomycin‐Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for Prevention

(2020) Gwendolyn M. Pais et al.   PHARMACOTHERAPY

A new rhodopsin R135W mutation induces endoplasmic reticulum stress and apoptosis in retinal pigment epithelial cells

(2019) Yixin Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular Functions and Mechanisms of Action of Small Heat Shock Proteins

(2019) Axel Mogk et al.   Annual Review of Microbiology

Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stress

(2019) Hao Liu et al.   Redox Biology

Prostaglandin E1 attenuates high glucose-induced apoptosis in proximal renal tubular cells by inhibiting the JNK/Bim pathway

(2019) Yu-han Zhang et al.   ACTA PHARMACOLOGICA SINICA

Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus, and Lentiviral Vectors After Intravenous and Direct Kidney Injections

(2019) Jeffrey D. Rubin et al.   HUMAN GENE THERAPY

Regulation of HSF1 protein stabilization: An updated review

(2018) Chao Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs)

(2018) Tim Sonntag et al.   FEBS Journal

Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis

(2018) Xiaolei Wang et al.   HEPATOLOGY

Effects of Dapagliflozin on Circulating Markers of Phosphate Homeostasis

(2018) Maarten A. de Jong et al.   Clinical Journal of the American Society of Nephrology

Atg7 mediates renal tubular cell apoptosis in vancomycin nephrotoxicity through activation of PKC-δ

(2018) Xuan Xu et al.   FASEB JOURNAL

SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress

(2017) Xiaobin Zheng et al.   HEPATOLOGY

Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells

(2017) Hui Sun et al.   Translational Neurodegeneration

Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis

(2016) Hai-De Qin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

(2016) Fabrizio Miranda et al.   CANCER CELL

A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel

(2016) Jinhua Zhou et al.   CLINICAL CANCER RESEARCH

Kidney-specific knockout ofSav1in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway

(2016) Tomoki Kai et al.   JOURNAL OF PATHOLOGY

Endoplasmic reticulum stress and its effects on renal tubular cells apoptosis in ischemic acute kidney injury

(2016) Yan Xu et al.   RENAL FAILURE

Activation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis

(2016) H-H Wang et al.   Cell Death & Disease

Endoplasmic reticulum stress in kidney function and disease

(2015) Mai Taniguchi et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

RTN1 mediates progression of kidney disease by inducing ER stress

(2015) Ying Fan et al.   Nature Communications

SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo

(2014) Jinyoung Park et al.   DIABETES

Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

(2014) M. Zhan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer

(2014) Hélène Bon et al.   MOLECULAR CANCER RESEARCH

SIK2 regulates insulin secretion

(2014) Bengt-Frederik Belgardt et al.   NATURE CELL BIOLOGY

Proteostasis in endoplasmic reticulum—new mechanisms in kidney disease

(2014) Reiko Inagi et al.   Nature Reviews Nephrology

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

(2014) Kashyap Patel et al.   Nature Communications

Diabetic kidney disease and immune modulation

(2013) Fionnuala B Hickey et al.   CURRENT OPINION IN PHARMACOLOGY

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy

(2013) L. Xiao et al.   DIABETES

Interaction between Salt-inducible Kinase 2 (SIK2) and p97/Valosin-containing Protein (VCP) Regulates Endoplasmic Reticulum (ER)-associated Protein Degradation in Mammalian Cells

(2013) Fu-Chia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy

(2013) Fu-Chia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes

(2012) Yiguo Wang et al.   NATURE

The pathogenic role of the renal proximal tubular cell in diabetic nephropathy

(2012) S. C. W. Tang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?

(2012) Joseph V. Bonventre   SEMINARS IN NEPHROLOGY

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma

(2011) Dhong Hyun Lee et al.   CANCER LETTERS

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy

(2011) M. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Endoplasmic reticulum stress as a progression factor for kidney injury

(2010) Reiko Inagi   CURRENT OPINION IN PHARMACOLOGY

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

(2010) Julien Bricambert et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The regulation and function of mammalian AMPK-related kinases

(2009) N. J. Bright et al.   Acta Physiologica

Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells

(2009) Nicolas Dejeans et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70

(2009) A R Stankiewicz et al.   CELL DEATH AND DIFFERENTIATION

The role of tubular injury in diabetic nephropathy

(2009) Caroline Jane Magri et al.   European Journal of Internal Medicine

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Dysfunction of the ER chaperone BiP accelerates the renal tubular injury

(2008) Keita Kimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

(2008) M. T. Lindenmeyer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SIK2 Can be Activated by Deprivation of Nutrition and It Inhibits Expression of Lipogenic Genes in Adipocytes

(2008) Jing Du et al.   Obesity